Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Multidomain and multimeric proteins: structural and mechanical insights

2012/05/B/NZ1/00631

Keywords:

protein structure multidomain proteins disorder ensemble refinement mechanostability protein complexes

Descriptors:

  • NZ1_3: Biophysics
  • NZ1_4: Structural biology
  • ST4_7: Electrochemistry, microfluidics in chemistry, sensors

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Fizyki PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Bartosz Różycki 

Number of co-investigators in the project: 2

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 287 056 PLN

Project start date (Y-m-d): 2013-03-06

Project end date (Y-m-d): 2015-06-05

Project duration:: 27 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. serwer komputerowy (75 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Large, dynamic, multi-protein complexes: A challenge for structural biology
    Authors:
    Bartosz Różycki, Evzen Boura
    Academic press:
    Journal of Physics: Condensed Matter (rok: 2014, tom: 26, strony: 463103), Wydawca: IOP PUBLISHING LTD
    Status:
    Published
    DOI:
    10.1088/0953-8984/26/46/463103 - link to the publication
  2. The crystal structure of the phosphatidylinositol 4-kinase II-alpha
    Authors:
    Adriana Baumlova, Dominika Chalupska, Bartosz Różycki, Marko Jovic, Eva Wisniewski, Martin Klima, Anna Dubankova, Daniel P Kloer, Radim Nencka, Tamas Balla, Evzen Boura
    Academic press:
    EMBO Reports (rok: 2014, tom: 15, strony: 1085-1092), Wydawca: WILEY-BLACKWELL
    Status:
    Published
    DOI:
    10.15252/embr.201438841 - link to the publication
  3. Citrate synthase proteins in extremophilic organisms: Studies within a structure-based model
    Authors:
    Bartosz Różycki, Marek Cieplak
    Academic press:
    Journal of Chemical Physics (rok: 2014, tom: 141, strony: 235102), Wydawca: American Institute of Physics
    Status:
    Published
    DOI:
    10.1063/1.4903747 - link to the publication
  4. Unbinding and unfolding of adhesion protein complexes through stretching: Interplay between shear and tensile mechanical clamps
    Authors:
    Bartosz Różycki, Łukasz Mioduszewski, Marek Cieplak
    Academic press:
    Proteins: Structure, Function and Bioinformatics (rok: 2014, tom: 82, strony: 3144–3153), Wydawca: WILEY-BLACKWELL
    Status:
    Published
    DOI:
    10.1002/prot.24674 - link to the publication
  5. Large conformational fluctuations of the multi-domain xylanase Z of Clostridium thermocellum
    Authors:
    Bartosz Różycki, Marek Cieplak, Mirjam Czjzek
    Academic press:
    Journal of Structural Biology (rok: 2015, tom: 191, strony: 68-75), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jsb.2015.05.004 - link to the publication