Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Nucleotide sugar transporters as organizing centers of glycosylation-related macromolecular complexes

2020/39/B/NZ3/00825

Keywords:

N-glycosylation glycosyltransferases nucleotide sugar transporters protein-protein interactions Golgi apparatus endoplasmic reticulum bioluminescence

Descriptors:

  • NZ3_001:
  • NZ2_003:
  • NZ1_001:

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Wrocławski, Wydział Biotechnologii

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Dorota Justyna Maszczak-Seneczko 

Number of co-investigators in the project: 6

Call: OPUS 20 - announced on 2020-09-15

Amount awarded: 1 570 140 PLN

Project start date (Y-m-d): 2021-06-24

Project end date (Y-m-d): 2025-06-23

Project duration:: 48 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  1. An interaction between SLC35A1 and ST3Gal4 is differentially affected by CDG-causing mutations in the SLC35A1 gene
    Authors:
    Wojciech Wiertelak, Dorota Maszczak-Seneczko, Mariusz Olczak
    Academic press:
    Biochemical and Biophysical Research Communications (rok: 2022, tom: 635, strony: 46-51), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.019 - link to the publication
  2. Subcellular imaging of MGAT1/MGAT2 homo- and heteromers in living cells using bioluminescence microscopy
    Authors:
    Wojciech Wiertelak, Mariusz Olczak, Dorota Maszczak-Seneczko
    Academic press:
    Biochemical and Biophysical Research Communications (rok: 2024, tom: 734, strony: 150470), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbrc.2024.150470 - link to the publication
  3. An interaction between SLC35A1 and ST3Gal4 is differentially affected by CDG-causing mutations in the SLC35A1 gene
    Authors:
    Wojciech Wiertelak, Dorota Maszczak-Seneczko, Mariusz Olczak
    Academic press:
    Biochemical and Biophysical Research Communications (rok: 2022, tom: 635, strony: 46-51), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.019 - link to the publication
  4. Delivery of Nucleotide Sugars to the Mammalian Golgi: A Very Well (un)Explained Story
    Authors:
    Dorota Maszczak-Seneczko, Maciej Wiktor, Edyta Skurska, Wojciech Wiertelak, Mariusz Olczak
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 8648), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23158648 - link to the publication
  5. SLC35A2 deficiency reduces protein levels of core 1 β-1,3-galactosyltransferase 1 (C1GalT1) and its chaperone Cosmc and affects their subcellular localization
    Authors:
    Wojciech Wiertelak, Karolina Chabowska, Bożena Szulc, Yelyzaveta Zadorozhna, Mariusz Olczak, Dorota Maszczak-Seneczko
    Academic press:
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (rok: 2023, tom: 1870, strony: 119462-119475), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2023.119462 - link to the publication

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