Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Structural and thermodynamic studies of complexes avidin with luminescents and metallocenes biotin derivatives

2013/11/N/ST5/01296

Keywords:

metallocene biotin derivatives avidin luminescence protein crystallography ITC

Descriptors:

  • ST5_16:
  • ST5_20:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Paweł Strzelczyk 

Number of co-investigators in the project: 2

Call: PRELUDIUM 6 - announced on 2013-09-16

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2014-08-19

Project end date (Y-m-d): 2016-08-18

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Komputer ze stacją graficzną 3D (10 400 PLN)
  2. Zestaw do mrożenia i transportu kryształów (14 200 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Structural Characterization of the Avidin Interactions with Fluorescent Pyrene-Conjugates: 1-Biotinylpyrene and 1-Desthiobiotinylpyrene
    Authors:
    Paweł Strzelczyk, Damian Plażuk, Janusz Zakrzewski, Grzegorz Bujacz
    Academic press:
    Molecules (rok: 2016, tom: 21, strony: 1270), Wydawca: MDPI AG
    Status:
    Published
    DOI:
    10.3390/molecules21101270 - link to the publication
  2. Ferrocene-Biotin Conjugates: Synthesis, Structure, Cytotoxic Activity and Interaction with Avidin
    Authors:
    Andrzej Błauż, Błażej Rychlik, Anna Makal, Katarzyna Szulc, Paweł Strzelczyk, Grzegorz Bujacz, Janusz Zakrzewski, Krzysztof Woźniak, Damian Plażuk
    Academic press:
    ChemPlusChem (rok: 2016, tom: 81, strony: 1191-1201), Wydawca: Wiley-VCH Verlag GmbH & Co. KGaA
    Status:
    Published
    DOI:
    10.1002/cplu.201600320 - link to the publication
  3. Crystal structure and ligand affinity of avidin in the complex with 4′-hydroxyazobenzene-2-carboxylic acid
    Authors:
    Paweł Strzelczyk, Grzegorz Bujacz
    Academic press:
    Journal of Molecular Structure (rok: 2016, tom: 1109, strony: 232-238), Wydawca: ELSEVIER SCIENCE BV
    Status:
    Published
    DOI:
    10.1016/j.molstruc.2016.01.013 - link to the publication

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