Projects funded by the NCN

EMMPRIN role in rat model of subarachnoid hemorrhage and in minocycline neuroprotective mechanisms.

Call: PRELUDIUM 6 , Panel: NZ7

Principal investigator: Daria Irena Gendosz

Śląski Uniwersytet Medyczny w Katowicach, Wydział Lekarski w Katowicach

The research of molecular markers for neuroprotective effect of tetrahydroisoquinolines based on various eksperimental m...

Call: OPUS 4 , Panel: NZ7

Principal investigator: dr Agnieszka Wąsik

Instytut Farmakologii PAN

Positioning the aryl hydrocarbon receptor (AhR) as a new target for pharmacotherapy of sporadic Alzheimer disease: verif...

Call: OPUS 28 , Panel: NZ7

Principal investigator: prof. Małgorzata Kajta

Instytut Farmakologii PAN

Cannabidiol as a Neuroprotective Therapy: Are Brain Regeneration Mechanisms After Perinatal Hypoxia-Ischemia Sex-Depende...

Call: SONATA 20 , Panel: NZ7

Principal investigator: dr Hanna Kletkiewicz

Uniwersytet Mikołaja Kopernika

Effect of Urolithin A on gut microbiota and intestinal integrity contributing to neuroprotective effects in a model of P...

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Olga Wojciechowska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

First-in-class dual modulators of necroptosis kinases and 5-HT6 receptors as an innovative approach to develop an effect...

Call: OPUS 26 , Panel: NZ7

Principal investigator: prof. Jadwiga Handzlik

Uniwersytet Jagielloński, Collegium Medicum

The inhibition of NMDAR and TRPM4 coupling - a hope for novel therapeutic target for the treatment of the ischemic brain...

Call: SONATA BIS 13 , Panel: NZ7

Principal investigator: dr Bartosz Sebastian Pomierny

Uniwersytet Jagielloński, Collegium Medicum

Neuroprotective effect of SGLT2i: direct influence on amyloid-β related pathology

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Agnieszka Pawlos

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian b...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Bernadeta Angelika Pietrzak-Wawrzyńska

Instytut Farmakologii PAN

Neuroprotective properties of β-cyclodextrin-1,2,4-triazole inclusion complexes

Call: PRELUDIUM BIS 4 , Panel: NZ7

Principal investigator: prof. Tomasz Sylwester Plech

Uniwersytet Medyczny w Lublinie

The role of GPR39 receptor in the mechanism of antidepressant action

Call: OPUS 2 , Panel: NZ7

Principal investigator: dr Katarzyna Młyniec

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

New positive allosteric modulators of EAAT2 glutamate transporter as candidates for treatment of neurological and psychi...

Call: OPUS 23 , Panel: NZ7

Principal investigator: prof. Krzysztof Tomasz Kamiński

Uniwersytet Jagielloński, Collegium Medicum

Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Karolina Barbara Przepiórska-Drońska

Instytut Farmakologii PAN

New post-treatment strategy against stroke and perinatal asphyxia – a novel approach based on a selective activation of ...

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Agnieszka Wnuk

Instytut Farmakologii PAN

Multifunctional plant systems as a complex way of providing neuroprotective activity

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: dr Anna Stasiłowicz-Krzemień

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Pharmacological evaluation of possible neuroprotective strategies in novel genetic mouse models of progressive neurodege...

Call: OPUS 2 , Panel: NZ7

Principal investigator: dr Grzegorz Kreiner

Instytut Farmakologii PAN

Selective activation of non-nuclear Estrogen Receptor signaling with PaPE-1 as a novel therapeutic approach for sporadic...

Call: OPUS 20 , Panel: NZ7

Principal investigator: prof. Małgorzata Kajta

Instytut Farmakologii PAN

New generation teranostatic nanocarriers for detection, diagnosis andneuroprotective treatment of ischemic stroke brain ...

Call: OPUS 20 , Panel: NZ7

Principal investigator: prof. Piotr Warszyński

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Strategies to protect against methamphetamine-induced neurotoxicity

Call: OPUS 18 , Panel: NZ7

Principal investigator: prof. Michał Jan Toborek

Akademia Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach, Instytut Fizjoterapii i Nauk o Zdrowiu

Evaluation of molecular mechanisms of neuroprotective action of dental pulp stromal cells in an ex vivo organotypic mode...

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: dr Natalia Helena Bryniarska-Kubiak

Instytut Farmakologii PAN

Involvement of astrocytes in the neuroprotective mechanism evoked by enhancement of noradrenergic transmission in trasng...

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: Justyna Beata Barut

Instytut Farmakologii PAN

Theranostic nanocarriers for drug delivery in central nervous system disorders

Call: GRIEG 1 , Panel: ST5

Principal investigator: prof. Piotr Warszyński

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Neuroprotective properties of 5-HT6 receptor ligands in the group of 2-arylpyrrole derivatives – a new insight into neur...

Call: PRELUDIUM 17 , Panel: NZ7

Principal investigator: Marcin Józef Drop

Uniwersytet Jagielloński, Collegium Medicum

Searching for effective strategies to protect neuronal cells against hypoxia and ischemia: Identification of neuroprotec...

Call: OPUS 16 , Panel: NZ7

Principal investigator: prof. Małgorzata Kajta

Instytut Farmakologii PAN

How microglia-astrocyte interaction affects neuronal functioning in the dopaminergic system. Analysis of the protective ...

Call: OPUS 14 , Panel: NZ7

Principal investigator: dr Katarzyna Zofia Kuter

Instytut Farmakologii PAN

Expression of microRNA and its effect on the level of proteins with neuroprotective properties in the pathogenesis of th...

Call: OPUS 14 , Panel: NZ7

Principal investigator: prof. Ireneusz Jacek Majsterek

Uniwersytet Medyczny w Łodzi, Wydział Lekarski; Oddział Lekarski

Urolithin A as a metabolite of ellagitannins with potential neuroprotective activity - the research of mechanisms of thi...

Call: SONATA 13 , Panel: NZ7

Principal investigator: dr Małgorzata Kujawska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Glaucoma neuroprotection with BDNF on the level of retinal and primary visual cortex

Call: PRELUDIUM 12 , Panel: NZ7

Principal investigator: Anna Wójcik- Gryciuk

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Investigation of the mechanisms of the neuroprotective effect of group II metabotropic receptors (mGluR2/3) agonist in a...

Call: PRELUDIUM 12 , Panel: NZ7

Principal investigator: dr Ewelina Małgorzata Bratek

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

The influence of body temperature during perinatal hypoxia on the level of neurotrophic-derived factor (BDNF) - new appr...

Call: PRELUDIUM 11 , Panel: NZ7

Principal investigator: Hanna Kletkiewicz

Uniwersytet Mikołaja Kopernika, Wydział Biologii i Ochrony Środowiska

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Call: SONATA 1 , Panel: NZ7

Principal investigator: dr Anna Gąsiorowska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

The influence of a new hybryd compound derived from 2-(2,5-dioxopyrrolidin-1-yl) propanamide on hippocampal neuroprotect...

Call: OPUS 10 , Panel: NZ7

Principal investigator: dr hab. Marta Andres-Mach

Instytut Medycyny Wsi im. Witolda Chodźki

Neuroprotective role of the GPR39 receptor in the central nervous system. Its relationship to Alzheimer Disease.

Call: OPUS 10 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Młyniec

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny