Projects funded by the NCN
Investigation of the mechanisms of the neuroprotective effect of group II metabotropic receptors (mGluR2/3) agonist in animal model of perinatal asphyxia
2016/23/N/NZ7/01942
Keywords:
hypoxia-ischemia perinatal asphyxia group II metabotropic glutamate receptors (mGluR2/3) agonist excitotoxicity
Descriptors:
- NZ7_14: Pharmacy, pharmacotherapy, pharmacology
- NZ7_12: Prevention of human diseases
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 12 - announced on 2016-09-15
Amount awarded: 99 840 PLN
Project start date (Y-m-d): 2017-08-25
Project end date (Y-m-d): 2020-02-24
Project duration:: 30 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- The activation of group II metabotropic glutamate receptors protects neonatal rat brains from oxidative stress injury after hypoxia-ischemia.Authors:Bratek E., Ziembowicz A., Bronisz A., Salinska E.Academic press:PLoS One. (rok: 2018, tom: 25;13(7), strony: 45310), Wydawca: Public Library of ScienceStatus:PublishedDOI:10.1371/journal.pone.0200933 - link to the publication
- Pretreatment with Group II Metabotropic Glutamate Receptor Agonist LY379268 Protects Neonatal Rat Brains from Oxidative Stress in an Experimental Model of Birth AsphyxiaAuthors:Bratek E., Ziembowicz A., Salinska E.Academic press:Brain Sci. (rok: 2018, tom: 8(3): 48, strony: 45302), Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)Status:PublishedDOI:10.3390/brainsci8030048 - link to the publication