Projects funded by the NCN

Synthesis and pharmacological properties of mono- di- and triheterocyclic azole derivatives as a hybrid receptor and PDE...

Call: OPUS 4 , Panel: NZ7

Principal investigator: prof. Maciej Henryk Pawłowski

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Metal-organic frameworks (MOFs) based on polytopic hydrazone ligands: synthesis, structure and physicochemical propertie...

Call: OPUS 4 , Panel: ST5

Principal investigator: dr hab. Dariusz Matoga

Uniwersytet Jagielloński, Wydział Chemii

The search for a common structural motif in newly discovered ligands of human ficolin H - endotoxins of Proteus spp.

Call: PRELUDIUM 4 , Panel: NZ6

Principal investigator: dr Aleksandra Agnieszka Man-Kupisińska

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

PHARMACOTHERAPY OF OSTEOARTHRITIS: TRPV1 AND CB1 RECEPTORS AND THEIR ENDOGENOUS LIGANDS AS NEW TARGETS FOR PHARMACOLOGIC...

Call: SONATA BIS 2 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Maria Starowicz-Bubak

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Search of novel multifunctional ligands targeting neurodegereneration processes.

Call: OPUS 4 , Panel: NZ7

Principal investigator: prof. Barbara Antonina Malawska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Taylor dispersion analysis in coiled capillaries at high flow rates - new tool in analytical chemistry for determination...

Call: OPUS 4 , Panel: ST4

Principal investigator: prof. Robert Hołyst

Instytut Chemii Fizycznej Polskiej Akademii Nauk

In the search for active compounds among ligands of serotonin, particularly 5-HT7, and dopamine receptors, with potentia...

Call: OPUS 1 , Panel: NZ4

Principal investigator: prof. Anna Małgorzata Wesołowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Design, synthesis and properties of novel hybrid materials based on pyridylphosphonic acids.

Call: PRELUDIUM 1 , Panel: ST5

Principal investigator: Magdalena Maria Wilk

Politechnika Wrocławska, Wydział Chemiczny

New ligands with P-P bond - synthesis and structural investigations

Call: HARMONIA 3 , Panel: ST5

Principal investigator: prof. Jerzy Paweł Pikies

Politechnika Gdańska, Wydział Chemiczny

Structural study of the complexes of hydrolytic enzymes with heteroorganic substrates and substrate analogs

Call: OPUS 3 , Panel: ST4

Principal investigator: dr hab. Jarosław Błaszczyk

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

Design and modular synthesis of tailor made catalysts of special properties, among others water-soluble and immobilized ...

Call: OPUS 3 , Panel: ST5

Principal investigator: dr Oleh Demchuk

Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Chemii

A new class of P-stereogenic cyclohexane-based diphosphine ligands - effective application of Birch reduction in organop...

Call: PRELUDIUM 3 , Panel: ST5

Principal investigator: Magdalena Jaklińska

Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Chemii

Pirymidine phosphorothioate analogues of nucleotides as multifunctional regulators of P2Y6 and P2Y14 nucleotide receptor...

Call: PRELUDIUM 3 , Panel: NZ5

Principal investigator: Edyta Węgłowska

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

New approach to synthesis of phosphono analogs of lignans. Synthesis of phosphonothuriferic acid.

Call: OPUS 3 , Panel: ST5

Principal investigator: dr Marek Koprowski

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

The synthesis of new optically active aziridine alcohols and their application in asymmetric synthesis.

Call: SONATA 3 , Panel: ST5

Principal investigator: dr hab. Michał Rachwalski

Uniwersytet Łódzki, Wydział Chemii, Katedra Chemii Organicznej i Stosowanej

Influence of PPAR-gama receptor agonists on antitumor activity of photodynamic therapy.

Call: PRELUDIUM 3 , Panel: NZ5

Principal investigator: dr Piotr Marek Mrówka

Warszawski Uniwersytet Medyczny, Wydział Nauki o Zdrowiu

Studies on activity and immunogenicity of baculovirus-expressed recombinant Plasmodium falciparum EBA-140 ligand binding...

Call: PRELUDIUM 3 , Panel: NZ6

Principal investigator: dr Joanna Maria Rydzak

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Synthesis, structure and reactivity of chiral-at-metal vanadium complexes in aspect of enantioselective catalyst.

Call: PRELUDIUM 3 , Panel: ST5

Principal investigator: Ewa Magdalena Kober

Uniwersytet Wrocławski, Wydział Chemii

LCAP biomimetics - alicyclic amine derivatives as a new class of monoaminergic receptor ligands

Call: OPUS 3 , Panel: NZ7

Principal investigator: dr hab. Paweł Maria Zajdel

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Analysis of biologically active secondary metabolites in in vitro cultures of Phyllanthus amarus and Phyllanthus glaucus...

Call: PRELUDIUM 3 , Panel: NZ7

Principal investigator: dr Barbara Sparzak-Stefanowska

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

The role of glioma-derived signaling molecules in polarization of macrophages and shaping immune microenvironment

Call: MAESTRO 2 , Panel: NZ3

Principal investigator: prof. Bożena Kamińska-Kaczmarek

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

Search for new "drug-like" molecules designed as adenosine receptors ligands

Call: HARMONIA 2 , Panel: NZ4

Principal investigator: prof. Katarzyna Justyna Kieć-Kononowicz

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Modeling spectroscopic properties of high-pressure probes for HMF-EMR studies

Call: HARMONIA 2 , Panel: ST3

Principal investigator: prof. Czesław Zygmunt Rudowicz

Zachodniopomorski Uniwersytet Technologiczny w Szczecinie, Wydział Inżynierii Mechanicznej i Mechatroniki; Instytut Fizyki

The effects of histamine receptor signalling suppression on the course and structural and functional consequences of hea...

Call: HARMONIA 2 , Panel: NZ4

Principal investigator: prof. Wiesława Agnieszka Fogel

Uniwersytet Medyczny w Łodzi, Wydział Wojskowo-Lekarski; Zakład Biochemii Hormonów

Probing molecular recognition by mass spectrometry. A case study: Examination of properties of non-covalent complexes of...

Call: SONATA 2 , Panel: ST4

Principal investigator: dr Magdalena Zimnicka

Instytut Chemii Organicznej Polskiej Akademii Nauk

EFFECTS OF ADENOSINE A2A RECEPTOR LIGANDS ON BEHAVIORAL EFFECTS OF ABUSED DRUG (COCAINE) AND NATURAL REWARD (FOOD) USING...

Call: PRELUDIUM 2 , Panel: NZ7

Principal investigator: Karolina Agnieszka Wydra

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Solution NMR investigations of human cystatin C - structure, dynamics and protein-ligand interactions.

Call: PRELUDIUM 2 , Panel: ST4

Principal investigator: Martyna Ewa Maszota-Zieleniak

Uniwersytet Gdański, Wydział Chemii

Conjugated linoleic acid (CLA)-induced transcriptional activation of PPAR-an investigation of molecular machanisms of pu...

Call: OPUS 2 , Panel: NZ9

Principal investigator: prof. Teresa Leszczyńska

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Technologii Żywności

New bioinformatics method for predicting ligand-binding sites in RNA structures

Call: PRELUDIUM 2 , Panel: NZ2

Principal investigator: dr Anna Philips

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

The mast cell response to synthetic analogues of viral genomes (TLR3 and TLR7 ligands).

Call: PRELUDIUM 2 , Panel: NZ6

Principal investigator: dr Piotr Michał Witczak

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

Development of a new scoring function for models of protein-small molecule complexes and its use for studying the mechan...

Call: PRELUDIUM 2 , Panel: NZ2

Principal investigator: dr Irina Tuszyńska

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

Mechanisms of contact sensitivity response (CS) mediated via NK cells activated by Toll like receptor (TLR) ligands in m...

Call: OPUS 2 , Panel: NZ6

Principal investigator: dr Monika Majewska-Szczepanik

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Nauk o Zdrowiu

L-SWITCH: towards tailor-made molecular switches for specific applications – understanding of transition-metal coordinat...

Call: OPUS 28 , Panel: ST4

Principal investigator: dr hab. Katarzyna Natalia Jarzembska

Uniwersytet Warszawski

Implementation of Sustainable Sustainable Chemical Synthesis: Harnessing the Power of 3d-Electron Metal Compounds

Call: SONATA BIS 14 , Panel: ST4

Principal investigator: dr hab. Krzysztof Kuciński

Uniwersytet im. Adama Mickiewicza w Poznaniu

A new generation of environmentally friendly two-component additives with foaming and anti-aging properties for applicat...

Call: OPUS 27 , Panel: ST8

Principal investigator: prof. Wojciech Franus

Politechnika Lubelska

Dual Se-containing 5-HT1A and 5-HT7 biased agonists activating sigma-1 receptor as a hope of finding fast-acting antidep...

Call: OPUS 27 , Panel: NZ7

Principal investigator: prof. Karolina Anna Pytka

Uniwersytet Jagielloński

Cyclic triel carbenoids as auxiliary ligands for ruthenium-based olefin metathesis catalysts

Call: PRELUDIUM 23 , Panel: ST4

Principal investigator: Tymoteusz Marek Basak

Uniwersytet Warszawski

Cobalt and Iron Complexes With Aminophosphine Ligands: Catalysts Design for Organic and Organometallic Synthesis

Call: SONATINA 8 , Panel: ST4

Principal investigator: dr Hanna Maria Stachowiak-Dłużyńska

Fundacja Uniwersytetu im. Adama Mickiewicza w Poznaniu

Surface-Interface engineering in constructing multi-dimensional functional hybrid piezophotocatalysts for redox selectiv...

Call: OPUS 26 , Panel: ST5

Principal investigator: prof. Juan Carlos Colmenares Quintero

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Deciphering the promiscuous bioinorganic chemistry of putative copper transporters in bacteria

Call: SONATA 19 , Panel: ST5

Principal investigator: dr Aleksandra Anna Hecel-Czaplicka

Uniwersytet Wrocławski, Wydział Chemii

Insights in the phenylpropanoid transport in model legume plant Medicago truncatula

Call: SONATA 19 , Panel: NZ9

Principal investigator: dr Wanda Ada Biała-Leonhard

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Playing with Carbene Ligand Rigidity to Control Olefin Metathesis Stability, Productivity and Selectivity

Call: OPUS 26 , Panel: ST4

Principal investigator: prof. Karol Lesław Grela

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Electronic Structure and Electron Transfer Reactions in Selected Molecular Prototypes Involving Non-innocent Ligands: An...

Call: OPUS 2 , Panel: ST5

Principal investigator: dr Piotr Paweł Zarzycki

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Exploiting chemical modification of coffee waste and lignin: a novel approach for sustainable energy storage systems

Call: OPUS 26 , Panel: ST11

Principal investigator: dr Artur Ciesielski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

Crownphyrins - hybrids of crown ethers and porphyrins, constituting macrocyclic platforms for the construction of two- a...

Call: PRELUDIUM BIS 5 , Panel: ST4

Principal investigator: dr hab. Bartosz Jakub Szyszko

Uniwersytet Wrocławski, Wydział Chemii

Development of novel bio-delignification approach for upgrading crude lignocellulose resources into advanced biofuels

Call: OPUS 25 , Panel: ST8

Principal investigator: dr Muhammad Bilal

Politechnika Gdańska

"I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr...

Call: OPUS 25 , Panel: NZ7

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Optimization of coarse-grained molecular dynamics simulations for tunnel exploration of large proteins with buried activ...

Call: PRELUDIUM 22 , Panel: NZ2

Principal investigator: Nishita Mandal

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

New applications of non-conventional nonempirical methodologies for the analysis of catalytic and inhibitory properties ...

Call: OPUS 25 , Panel: ST4

Principal investigator: dr Edyta Dyguda-Kazimierowicz

Politechnika Wrocławska

Study of ligand binding and activation processes of formyl, opioid and cannabinoid G-protein-coupled receptors

Call: OPUS 2 , Panel: NZ1

Principal investigator: prof. Sławomir Hubert Filipek

Uniwersytet Warszawski, Wydział Chemii