Deciphering the promiscuous bioinorganic chemistry of putative copper transporters in bacteria

2023/51/D/ST5/01798

Keywords

Descriptors

  • ST5_14: Chemia biologiczna
  • ST5_10: Chemia koordynacyjna, supramolekularna
  • ST5_15: Chemia medyczna

Panel

ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution

Uniwersytet Wrocławski, Wydział Chemii

Voivodeship: dolnośląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Aleksandra Anna Hecel-Czaplicka

Number of co-investigators in the project: 4

Call

SONATA 19 – announced on 2023-09-18

Amount awarded
1 794 620 PLN
Project start date
2024-07-10
Project end date
2027-07-09
Project duration
36 months (the same as in the proposal)
Project status
Pending project

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (4)

  1. Two sites, two stories: sequence-driven divergence in Cu(II) and Zn(II) binding to CusF

    Authors:
    Pakowski Michał, Hecel Aleksandra*
    Academic press:
    Dalton Transactions (year: 2025, volume: 54, pages: 15441-15454), Publisher: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D5DT01770J – link to the publication
  2. AdcA lipoprotein involved in Zn(ii) transport in Streptococcus mutans – is it as metal-specific as expected?

    Authors:
    Garstka Kinga, Hecel Aleksandra*, Kozłowski Henryk, Domínguez-Martín Alicia, Szewczyk Krzysztof, Rowińska-Żyrek Magdalena
    Academic press:
    Dalton Transactions (year: 2025, volume: 54, pages: 6795-6804), Publisher: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/d5dt00131e – link to the publication
  3. Small Cysteine-Rich Motif, Big Function─Metal-Driven Dimerization of the CopY C-Terminal Fragment

    Authors:
    Hecel Aleksandra*, Kola Arian, Domínguez-Martín Alicia, Valensin Daniela
    Academic press:
    Inorganic Chemistry (year: 2025, volume: 64, pages: 22615-22630), Publisher: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.inorgchem.5c03226?urlappend=%3Fref%3DPDF&jav=VoR&rel=cite-as – link to the publication
  4. Thiol, His–His Motif, and the Battle over Cu(II) in the Relationship of CopM Metallophore and OprC Outer Membrane Protein

    Authors:
    Hecel Aleksandra*, Kola Arian, Valensin Daniela, Witkowska Danuta
    Academic press:
    Inorganic Chemistry (year: 2025, volume: 64, pages: 2936-2950), Publisher: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.inorgchem.4c05101 – link to the publication

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