Search results

1. Novel 2,4-disubstituted pyridine derivatives - synthesis, antimycobacterial activity in vitro, pharmacophore model, mole…

Principal investigator: dr hab. Katarzyna Małgorzata Gobis

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Call: OPUS 13, Panel: NZ7

2. Tick-borne encephalitis virus protease as a molecular target for novel inhibitors and activity-based probes

Principal investigator: dr Renata Grzywa

Politechnika Wrocławska

Call: OPUS 28, Panel: NZ6

3. Yeast DNA topoisomerase II as a model molecular target for novel antifungalcompounds

Principal investigator: dr hab. Iwona Aniela Gabriel

Politechnika Gdańska, Wydział Chemiczny

Call: OPUS 23, Panel: NZ6

4. Enzymes of the L-methionine biosynthetic pathway as novel moleculartargets for antifungal chemotherapy

Principal investigator: dr hab. Iwona Aniela Gabriel

Politechnika Gdańska, Wydział Chemiczny

Call: OPUS 20, Panel: NZ7

5. New 2(5H)-furanone derivatives with tailored hydrophobicity of substitutents - synthesis, molecular targets, mechanism o…

Principal investigator: prof. Krzysztof Zdzisław Walczak

Politechnika Śląska, Wydział Chemiczny

Call: OPUS 11, Panel: NZ7

6. Cuproptosis, a novel pathway of regulated cell death as a therapeutic target in treatment-naïve and targeted therapy-res…

Principal investigator: dr hab. Mariusz Łukasz Hartman

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: OPUS 25, Panel: NZ5

7. Pathogenesis of ovarian cancer survival in non-adhesion conditions: transcriptomic assessment and studies of molecular t…

Principal investigator: dr Anna Stachurska

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Call: PRELUDIUM 2, Panel: NZ1

8. Human annexin A1 and A2, and their phosphorylated forms, as a molecular target of metal-dependent hydrolysis of peptide …

Principal investigator: dr Tomasz Frączyk

Instytut Biochemii i Biofizyki PAN

Call: SONATA 1, Panel: NZ1

9. Structural and functional studies of the plant enzymes of arginine metabolism as molecular targets of novel plant protec…

Principal investigator: dr Bartosz Sekuła

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

Call: SONATA 17, Panel: NZ1

10. Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of en…

Principal investigator: prof. Mariusz Jaskólski

Instytut Chemii Bioorganicznej PAN

Call: OPUS 19, Panel: NZ1

11. The H3K27M oncohistone-centred molecular mechanisms as therapeutic targets in pediatric malignant diffuse midline glioma…

Principal investigator: dr Katarzyna Leszczyńska

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: SONATA BIS 14, Panel: NZ3

12. Prohepcidin as a molecular target of cadmium binding

Principal investigator: Dawid Płonka

Instytut Biochemii i Biofizyki PAN

Call: PRELUDIUM 16, Panel: ST4

13. Polyamines - a new metabolic switch for barley leaf senesence: developing molecular basis of the network regulation of t…

Principal investigator: dr hab. Ewa Anna Sobieszczuk-Nowicka

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: OPUS 15, Panel: NZ9

14. Aromatic aminotransferases from Candida albicans as molecular targets for antifungal chemotherapy.

Principal investigator: dr Iwona Aniela Gabriel

Politechnika Gdańska, Wydział Chemiczny

Call: OPUS 9, Panel: NZ6

15. Purine salvage pathway enzymes as a target for pathogenic organisma lacking de novo purine synthesis -cas study of Helic…

Principal investigator: prof. Maria Agnieszka Bzowska

Uniwersytet Warszawski, Wydział Fizyki

Call: HARMONIA 7, Panel: NZ1

16. Identification and structural characterization of the primordial cytotoxic conformers of the amyloidogenic cascade: Idea…

Principal investigator: prof. Marek Cieplak

Instytut Fizyki PAN

Call: UNISONO, Panel: NZ1

17. Targeting REST and KAISO: A Promising Approach for Glioblastoma Treatment

Principal investigator: dr hab. Bartosz Stefan Wojtaś

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 27, Panel: NZ2

18. Targeting IGH enhancer RNAs as a therapeutic approach in B-cell lymphoma

Principal investigator: dr hab. Agnieszka Dzikiewicz-Krawczyk

Instytut Genetyki Człowieka PAN

Call: SONATA BIS 13, Panel: NZ1

19. Bacterial toxin-antitoxin systems as novel target for the development of potential antibiotics

Principal investigator: dr Marcin Jan Równicki

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: PRELUDIUM 13, Panel: NZ1

20. BCL11b - Potential Therapeutic Target in T cell Neoplasms

Principal investigator: dr hab. Grzegorz Przybylski

Instytut Genetyki Człowieka PAN

Call: OPUS 5, Panel: NZ1

21. Multi-level molecular assessment based on laser microdissection of corneas to reveal biomarkers and therapeutic targets …

Principal investigator: prof. Marzena Magdalena Gajęcka

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Call: OPUS 16, Panel: NZ5

22. Toxic RNA with expanded trinucleotide repeats: pathomechanism and therapeutic targets of neurological diseases

Principal investigator: prof. Krzysztof Sobczak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: MAESTRO 12, Panel: NZ3

23. Inhibitors of BTLA-HVEM complex formation as potential targets for cancer immunotheraphy

Principal investigator: dr Marta Marcelina Spodzieja

Uniwersytet Gdański, Wydział Chemii

Call: SONATA 13, Panel: ST5

24. RNA regulatory networks as novel antimicrobial targets in multidrugs resistant bacteria

Principal investigator: dr Marek Żywicki

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: OPUS 13, Panel: NZ6

25. Structures of oligomers of amyloid beta peptides: Multiscale molecular simulations.

Principal investigator: Dinh Quoc Huy Pham

Instytut Fizyki PAN

Call: PRELUDIUM 14, Panel: NZ1

26. New molecular spin qubits connected with photoswitchable diarylethenes for the construction of quantum computers

Principal investigator: dr Katarzyna Barbara Rogacz

Uniwersytet Jagielloński

Call: PRELUDIUM 23, Panel: ST4

27. Identifying early biomarkers and molecular targets for therapeutic intervention in right ventricular dysfunction

Principal investigator: prof. Przemysław Błyszczuk

Uniwersytet Jagielloński

Call: OPUS 28, Panel: NZ5

28. Combining Advanced Metabolic MRI at 7 T with Genomics for Improved Characterization of Grade 2/3 IDH-wildtype Astrocytom…

Principal investigator: dr Grzegorz Stanisz

Uniwersytet Medyczny w Lublinie

Call: OPUS 28, Panel: NZ5

29. Electrochemically synthesized conducting polymers in molecular imprinting for chemical sensing of selected biomarkers

Principal investigator: dr Piyush Sindhu Sharma

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Call: SONATA 2, Panel: ST4

30. A systems biology approach to study the role and evolution of molecular pathways related to multicellularity

Principal investigator: dr Stanisław - Dunin-Horkawicz

Uniwersytet Warszawski, Wydział Biologii

Call: OPUS 19, Panel: NZ2

31. Approaching integrative genomics to identify molecular drivers of congenital heart disease

Principal investigator: dr Cecilia Lanny Winata

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: OPUS 15, Panel: NZ2

32. Characterization of Trypanosoma cruzi PEX5 as a promising target in Chagas disease

Principal investigator: dr hab. Grzegorz Dubin

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Call: HARMONIA 9, Panel: NZ1

33. Design and validation of multi-gene transcriptional signature as molecular diagnostic tool in paediatric brain tumours

Principal investigator: dr hab. Maria Anna Łastowska

INSTYTUT - POMNIK - CENTRUM ZDROWIA DZIECKA

Call: OPUS 11, Panel: NZ2

34. Badania białek związanych z układem odpornościowym człowieka jako celów molekularnych metalozależnej hydrolizy wiązania …

Principal investigator: Nina Ewa Wezynfeld

Instytut Biochemii i Biofizyki PAN

Call: ETIUDA 3, Panel: NZ1

35. Understanding the molecular basis of the regulation of activity of lysosome, a potential target of therapeutic intervent…

Principal investigator: prof. Magdalena Angelina Gabig-Cimińska

Uniwersytet Gdański, Wydział Biologii

Call: OPUS 14, Panel: NZ3

36. Multilevel approach to reveal elucive molecular basis of herbicide stress response in maize

Principal investigator: prof. Tomasz Twardowski

Instytut Chemii Bioorganicznej PAN

Call: MAESTRO 3, Panel: NZ9

37. CD147 as a novel multifunctional modulator of podocyte metabolism and exosome biogenesis: Identification of new molecula…

Principal investigator: dr hab. Agnieszka Piwkowska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 27, Panel: NZ4

38. Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design…

Principal investigator: Emilia Aleksandra Sługocka

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 22, Panel: NZ7

39. In search for molecular targets to overcome doxorubicin resistance in triple-negative breast cancer with the use of inno…

Principal investigator: Anna Karolina Pogorzelska

Narodowy Instytut Leków

Call: PRELUDIUM 20, Panel: NZ7

40. Identification of proline metabolic pathway as a molecular target for experimental regulation of apoptosis/autophagy in …

Principal investigator: prof. Jerzy Aleksander Pałka

Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Call: OPUS 7, Panel: NZ7

41. The application of molecular methods to identify and characterize Microsporidia in immunocompetent and immunosuppressed …

Principal investigator: dr Marta Mirosława Kicia

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Lekarski

Call: SONATA 3, Panel: NZ6

42. The study on the molecular mechanisms of cytotoxic activity of new compounds ZOT5-1-Me and ZOT5-1-Et in an experimental …

Principal investigator: dr Paulina Anna Tokarz

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: SONATA 16, Panel: NZ7

43. Antiparasitic properties and molecular target identification of new thiosemicarbazide and thiazolidinone derivates in To…

Principal investigator: Adrian Zdzisław Bekier

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: PRELUDIUM 16, Panel: NZ6

44. Decrypting the "sulfation code" of glycosaminoglycans for understanding their function in the extracellular matrix

Principal investigator: dr hab. Sergey Samsonov

Uniwersytet Gdański, Wydział Chemii

Call: OPUS 25, Panel: ST4

45. Analysis of somatic mutations in miRNA and miRNA-biogenesis genes to identify new therapeutic targets and biomarkers of …

Principal investigator: prof. Piotr Kozłowski

Instytut Chemii Bioorganicznej PAN

Call: MAESTRO 8, Panel: NZ2

46. Adaptation of Proteins to Evade Premature Degradation by the Ubiquitin-Proteasome System

Principal investigator: dr hab. Wojciech Mieczysław Pokrzywa

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: SONATA BIS 11, Panel: NZ1

47. Members of eIF4E protein family, their affinities towards 5' mRNA cap and protein binding partners: an interdisciplinary…

Principal investigator: prof. Edward Bolesław Darżynkiewicz

Uniwersytet Warszawski, Wydział Fizyki

Call: OPUS 4, Panel: NZ1

48. Fungal membrane modeling for selected antifungal compounds interactions

Principal investigator: dr Dominik Drabik

Politechnika Wrocławska

Call: SONATA 20, Panel: NZ9

49. Identification and characterization of novel players in HIV-1 RNA nuclear processing and export to dissect post-transcri…

Principal investigator: dr hab. Anna Kula-Pacurar

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Call: OPUS 23, Panel: NZ3

50. Evaluation of peroxiredoxins 1 and 2 along with the thioredoxin-thioredoxin reductase system as new therapeutic targets …

Principal investigator: dr hab. Radosław Zagożdżon

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

Call: OPUS 4, Panel: NZ7

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