Projects funded by the NCN

Targeting MMP-9 in Cancer Treatment: Computational Design and Experimental Validation of Potent, Safe Antitumor Agents

Call: SONATA BIS 15 , Panel: ST5

Principal investigator: dr Anna Żądło-Dobrowolska

Instytut Chemii Organicznej Polska Akademia Nauk

Development of Molecular and Supramolecular Tools to Exploit Human Copper(I) Homeostasis for Cancer Therapeutics

Call: SONATA BIS 15 , Panel: ST5

Principal investigator: dr JEENA Manayath Thekkeyil

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Integrative analysis of tRNA modification circuits and aminoacylation and their role in breast cancer model.

Call: OPUS 29 , Panel: NZ2

Principal investigator: dr Marcin Sajek

Instytut Genetyki Człowieka PAN

ECLECTIC: Endometrial Cancer multiLayered Evaluation of Clinico-Metabo-Histo-Molecular data for Translational Integrativ...

Call: PRELUDIUM 24 , Panel: NZ7

Principal investigator: Julia Zelkowska

Uniwersytet Medyczny w Białymstoku

Proteomic characterization, transcriptional and epigenetic regulation of drugtransporters in colorectal cancer

Call: PRELUDIUM 24 , Panel: NZ7

Principal investigator: Nina Ewa Komaniecka

Pomorski Uniwersytet Medyczny w Szczecinie

Role of the BRM- ERα interaction in the conferring of resistance to paclitaxel in BRG1-deficient cancers

Call: PRELUDIUM 24 , Panel: NZ7

Principal investigator: Karolina Gronkowska

Uniwersytet Łódzki

Effect of dietary modulation of RAGE/AGE axis on prostatic neuroendocrine differentiation and the efficacy of anticancer...

Call: OPUS 29 , Panel: NZ7

Principal investigator: dr Wawrzyniec Dobrucki

Gdański Uniwersytet Medyczny

Molecular pathways involved in nuclear membrane stress adaptation and its role in breast and prostate cancer

Call: OPUS 29 , Panel: NZ3

Principal investigator: dr Paulina Nastały

Gdański Uniwersytet Medyczny

M. bovis BCG extracellular vesicles as an alternative in bladder cancer immunotherapy

Call: PRELUDIUM 24 , Panel: NZ7

Principal investigator: Jakub Smoliński

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

TP53 mutations drive alternative FGFR1 splicing - the study of consequences for cancer progression and therapeutic oppor...

Call: PRELUDIUM 24 , Panel: NZ4

Principal investigator: Weronika Wojtyś

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Development of Red-Emitting Chiral Carbon Dots for Advanced Photodynamic Therapy (PDT)

Call: PRELUDIUM 24 , Panel: ST8

Principal investigator: Patryk Szymaszek

Politechnika Krakowska im. Tadeusza Kościuszki

Development of the fluorescence multifunctional biosensing system based on antisense oligonucleotide probes for the onco...

Call: PRELUDIUM 24 , Panel: ST4

Principal investigator: Hubert Grzegorz Grel

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie

Development of novel 1,3-selenazol-2-one derivatives incorporated into self-emulsifying drug delivery systems as a strat...

Call: OPUS 29 , Panel: NZ7

Principal investigator: dr hab. Robert Czarnomysy

Uniwersytet Medyczny w Białymstoku

Metabolic biomarkers of prostate cancer

Call: OPUS 29 , Panel: NZ7

Principal investigator: prof. Tomasz Łukasz Ruman

Politechnika Rzeszowska im. Ignacego Łukasiewicza

Simulation of complex biological systems assisted by artificial intelligence: language-controlled model for cancer thera...

Call: OPUS 29 , Panel: ST6

Principal investigator: prof. Witold Dzwinel

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie

LLT1 as a regulator of the immune response and a dual-target immunotherapy approach in colorectal cancer directed at NK ...

Call: OPUS 29 , Panel: NZ6

Principal investigator: dr Marzena Dorota Lenart

Uniwersytet Jagielloński

"The Role of Adipose Tissue and microRNA in the Progression of Clear Cell RenalCell Carcinoma".

Call: PRELUDIUM 24 , Panel: NZ4

Principal investigator: Dorota Małgorzata Kwapisz

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

UVC Persistent Phosphors for Next-Generation Photodynamic Cancer Therapy

Call: OPUS 29 , Panel: ST4

Principal investigator: dr Nadiia Rebrova

Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego PAN

Rola TRIM32 i TRIM34 w regulacji metabolizmu guza i mikrośrodowiska immunologicznego w raku jajnika

Call: PRELUDIUM 24 , Panel: NZ6

Principal investigator: Alicja Katarzyna Rajtak

Uniwersytet Medyczny w Lublinie

The role of inflammation and sex-specific mechanisms in the development and progression of hepatocellular carcinoma

Call: OPUS 29 , Panel: NZ4

Principal investigator: dr hab. Katarzyna Miękus

Uniwersytet Jagielloński

We are Left Without Oxygen—Now What?: Evaluation of Hypoxia-Inducible COL Family Genes in Glioblastoma Patients and Thei...

Call: OPUS 29 , Panel: NZ4

Principal investigator: prof. Ewa Izabela Balcerczak

Uniwersytet Medyczny w Łodzi

Smart Multiscale Encapsulation System: Hydrogel Macrocapsules with LbL Nanoparticles for Colorectal Cancer Treatment

Call: PRELUDIUM 24 , Panel: ST11

Principal investigator: Joanna Irena Szechyńska

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Intestinal barrier dysfunction as a risk factor for pancreatic ductal adenocarcinoma: impact of fatty acid intake, with ...

Call: PRELUDIUM 24 , Panel: NZ4

Principal investigator: Wojciech Michał Jankowski

Uniwersytet Medyczny w Łodzi

New aryl difluoromethylenephosphonic acid and thiazole conjugates as effective PTP1B inhibitors used in the treatment of...

Call: PRELUDIUM 24 , Panel: ST5

Principal investigator: Dominika Agnieszka Kołodziej-Sobczak

Uniwersytet Mikołaja Kopernika

New violacein derivatives as candidates for sonodynamic therapy against skin cancer

Call: SONATINA 9 , Panel: NZ7

Principal investigator: dr Daniel Ryszard Ziental

Uniwersytet Przyrodniczy w Poznaniu

Artificial intelligence in predicting treatment outcomes of abdominal cancers – implementation of machine learning and d...

Call: SONATINA 9 , Panel: NZ7

Principal investigator: dr Krzysztof Bartnik

Politechnika Warszawska

Next-Generation Exosome Therapy: Engineering NK Cell-Derived Vesicles for Targeted Cancer Treatment

Call: SONATINA 9 , Panel: NZ6

Principal investigator: dr Daria Nawrocka

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Alterations in host protein trafficking during Human papillomavirus infection and oncogenesis

Call: WEAVE-UNISONO , Panel: NZ6

Principal investigator: dr hab. Justyna Karolina Broniarczyk

Uniwersytet im. Adama Mickiewicza w Poznaniu

Developing histone deacetylase-inhibiting hybrid analogs of pleurocidin and their potential in the treatment of HPV-indu...

Call: SONATA 20 , Panel: NZ7

Principal investigator: dr hab. Ewelina Piktel

Uniwersytet Medyczny w Białymstoku

Reciprocal relationships in metastatic colorectal cancer and its niche – from adaptation to host organs to induced paren...

Call: OPUS 28 (LAP) , Panel: NZ2

Principal investigator: dr Michał Artur Bieńkowski

Gdański Uniwersytet Medyczny

Mind the gap! Plasmonic nanocavity for spectroscopic trapping of local molecularrearrangements in DNA upon epigenetic mo...

Call: OPUS 28 , Panel: ST4

Principal investigator: prof. Ewelina Wioletta Lipiec

Uniwersytet Jagielloński

Janus nanoparticles - research on the effect of the duality of carriers of the activesubstance in targeted therapy of sk...

Call: OPUS 28 , Panel: ST8

Principal investigator: dr hab. Bożena Anna Tyliszczak

Politechnika Krakowska im. Tadeusza Kościuszki

New Horizons in Cancer Immunotherapy: Blocking LAG-3/FGL1 Interactions

Call: SONATA 20 , Panel: NZ7

Principal investigator: dr Jacek Plewka

Uniwersytet Jagielloński

An innovative approach to the elimination of cancer cells in disseminated ovarian cancer in various preclinical models b...

Call: OPUS 28 , Panel: NZ5

Principal investigator: dr hab. Joanna Ewa Jazowiecka-Rakus

Kardio-Med Silesia Sp. z o.o.

Targeting Telomere Integrity as an Approach to Eradicate Cancer Cells

Call: OPUS 28 , Panel: NZ7

Principal investigator: dr Natalia Anna Maciejewska

Politechnika Gdańska

3d genome re-organization during induced senescence in pancreatic cancer – insights from analysis of single chromatin fi...

Call: OPUS 28 (LAP) , Panel: NZ5

Principal investigator: dr hab. Michał Ryszard Gdula

Uniwersytet im. Adama Mickiewicza w Poznaniu

Investigation of the mechanism of enhanced liposome delivery to tumors and its application for dual target immunotherapy

Call: OPUS 28 , Panel: NZ7

Principal investigator: dr hab. Tomasz Piotr Rygiel

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Environmental modulation of CDK4/6 inhibitor efficacy: Impact of mycotoxin alternariol exposure on anti-cancer therapies

Call: SONATA 20 , Panel: NZ5

Principal investigator: dr Anna Dominika Walczak-Szeffer

Uniwersytet Medyczny w Łodzi

Changes in the oral microbiome as an early cancer marker

Call: OPUS 28 , Panel: NZ5

Principal investigator: dr hab. Maja Kosecka-Strojek

Uniwersytet Jagielloński

Neutrophil Dynamics: Unveiling Anti-Tumor and Therapy Efficacy with the TUmor Neutrophil Immunotherapy on Chip (TUNIC) m...

Call: SONATA 20 , Panel: NZ6

Principal investigator: dr Martin Nurmik

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Analysis of the effects of proteotoxic stress on cholesterol homeostasis and its associations with cardiovascular diseas...

Call: OPUS 28 , Panel: NZ5

Principal investigator: prof. Wiesława Elżbieta Widłak

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Parallel microevolution of metabolic plasticity and chemoresistance of cancer cells: a key to understanding cancer relap...

Call: OPUS 28 , Panel: NZ3

Principal investigator: prof. Jarosław Piotr Czyż

Uniwersytet Jagielloński

Non-canonical Estrogen Receptor (ER) signalling in breast cancer progression

Call: OPUS 28 , Panel: NZ3

Principal investigator: prof. Rafał Sebastian Sądej

Gdański Uniwersytet Medyczny

Aptamer-mediated SERS/DEP Biosensors for proteomic analysis of extracellular vesicles of salivary gland tumors: towards ...

Call: OPUS 28 , Panel: ST4

Principal investigator: prof. Agnieszka Edyta Michota-Kamińska

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Harnessing NK cells and Graphene Oxide Nanoparticles for Pancreatic Ductal Adenocarcinoma Immunotherapy

Call: OPUS 28 (LAP) , Panel: NZ7

Principal investigator: prof. Iwona Maria Inkielewicz-Stępniak

Gdański Uniwersytet Medyczny

Canonical and non-canonical roles of DDK in oncogenesis: a cornerstone for the development of novel, potent anticancer t...

Call: SONATA BIS 14 , Panel: NZ3

Principal investigator: dr Jan Marian Suski

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Supramolecular nanoparticles able to block calcium channels in cancer cells

Call: SONATA BIS 14 , Panel: ST11

Principal investigator: dr hab. Marek Brzeziński

Centrum Badań Molekularnych i Makromolekularnych PAN

Quad-TNT: Quadruplex-Targeted Photo-Therapy for Triple-Negative Tumors

Call: SONATA BIS 14 , Panel: NZ5

Principal investigator: dr Marco Deiana

Politechnika Wrocławska

Molecular factors and pathomechanism of cancer-associated cachexia.

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr hab. Marcin Tomasz Skrzypski

Gdański Uniwersytet Medyczny

ERβ-mediated autophagy in colorectal cancer and its impact on carcinogenesis

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Julia Maria Lipowicz

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu