Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

SLC6A14 - an amino acid transporter upregulated in cancer: Role of chaperone proteins in transporter exit from endoplasmic reticulum in the perspective of cancer treatment

2015/19/B/NZ3/00049

Keywords:

amino acid transport chaperone proteins coatomer II (COPII) breast cancer

Descriptors:

  • NZ3_1: Cell biology
  • NZ3_2: Cell physiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Katarzyna Nałęcz 

Number of co-investigators in the project: 3

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 690 000 PLN

Project start date (Y-m-d): 2016-07-08

Project end date (Y-m-d): 2020-07-07

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Waga analityczna (18 000 PLN)
  2. Zasilacz do elktroforezy (8 500 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (2)
  1. Regulation of SLC6A14 trafficking in breast cancer cells by heat shock protein HSP90b
    Authors:
    Karolina Połosak, Anna Papierniak-Wygla˛dała, Katarzyna A. Nałe˛cz
    Academic press:
    Biochemical and Biophysical Research Communications (rok: 2022, tom: 614, strony: 41-46), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbrc.2022.05.011 - link to the publication
  2. Amino acid transporter SLC6A14 depends on heat shock protein HSP90 in trafficking to the cell surface
    Authors:
    Rogala-Koziarska K. Samluk Ł. Nałęcz K.A.
    Academic press:
    BBA - Mol. Cell Res (rok: 2019, tom: 1866, strony: 1544-1555), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.201908.009. - link to the publication
  1. Plasma membranę transporter SLC6A14 is controlled by cytosolic heat shock proteins
    Authors:
    Rogala-Koziarska K., Samluk Ł., Nałęcz K.A
    Conference:
    FEBS Congress (rok: 2018, ), Wydawca: FEBS
    Data:
    konferencja 7-12.07.2018
    Status:
    Published
  2. Amino acid plasma membrane transporter SLC6A14 interacts with cytosolic heat shock protein HSP90beta
    Authors:
    Rogala-Koziarska K, Nałęcz K.A.
    Conference:
    The 44th FEBS Congress "From Molecules to Living Systems" (rok: 2019, ), Wydawca: FEBS
    Data:
    konferencja 6-11 lipca 2019
    Status:
    Published

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy