Projects funded by the NCN

Dual Se-containing 5-HT1A and 5-HT7 biased agonists activating sigma-1 receptor as a hope of finding fast-acting antidep...

Call: OPUS 27 , Panel: NZ7

Principal investigator: prof. Karolina Anna Pytka

Uniwersytet Jagielloński

Evaluation of the relationship between doxorubicin resistance, epithelial-mesenchymal plasticity, and effects of selecte...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Dominika Kunachowicz

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista...

Call: OPUS 26 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

The role of the immune checkpoints in the pathomechanism of depressive disorders.

Call: OPUS 22 , Panel: NZ6

Principal investigator: prof. Marta Wanda Kubera

Instytut Farmakologii PAN

The influence of microplastics on the toxicity and fate of selected antidepressants

Call: OPUS 18 , Panel: NZ8

Principal investigator: prof. Grzegorz Leszek Nałęcz-Jawecki

Warszawski Uniwersytet Medyczny

The role of selected metabotropic glutamate receptors in the mechanism of rapid antidepressant effect of RS-ketamine and...

Call: OPUS 14 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

Instytut Farmakologii PAN

Pharmacological and optogenetic investigation of the mechanism of action of Deep Brain Stimulation of the ventromedial p...

Call: OPUS 13 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Role of oxidative stress and ceramide in the pathogenesis of depression and in the mechanizm of action of antidepressant...

Call: PRELUDIUM 12 , Panel: NZ5

Principal investigator: Justyna Józefa Brodowicz

Instytut Farmakologii PAN

Evaluation of interactions of aripiprazole, the atypical amtipsychotic drug, with the selected antidepressants in the ra...

Call: OPUS 12 , Panel: NZ7

Principal investigator: dr hab. Zofia Maria Rogóż

Instytut Farmakologii PAN

Modeling of quantitative structure-metabolic stability relationships as a tool to improve design of potential novel anti...

Call: OPUS 12 , Panel: NZ7

Principal investigator: prof. Tomasz Bączek

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

The effect of the metabotropic glutamatergic receptor ligands on potentiating the antidepressant-like actvity of scopola...

Call: PRELUDIUM 10 , Panel: NZ7

Principal investigator: Karolina Sylwia Podkowa

Instytut Farmakologii PAN

The role of inflammation, oxidative and nitrosative stress, tryptophan catabolites pathway and DNA base excision repair ...

Call: OPUS 10 , Panel: NZ7

Principal investigator: dr hab. Tomasz Śliwiński

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Functional dissection of three alpha(1)-adrenergic receptor subtypes in the effects of antidepressant drugs: exploitatio...

Call: OPUS 9 , Panel: NZ7

Principal investigator: prof. Irena Maria Nalepa

Instytut Farmakologii PAN

Investigation of the effects and mechanisms of action of Deep Brain Stimulation in two animal models of treatment-resist...

Call: OPUS 9 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Role of the NLRP3 inflammasome in the mechanisms of action of antidepressant drugs - study in an animal model of depress...

Call: PRELUDIUM 9 , Panel: NZ7

Principal investigator: dr Ewa Izabela Trojan

Instytut Farmakologii PAN

Molecular mechanism of action of antidepressant drugs in the in vitro model of contact allergy in the human cell line Ha...

Call: PRELUDIUM 7 , Panel: NZ6

Principal investigator: Katarzyna Curzytek

Instytut Farmakologii PAN

Research of mechanisms of antidepressant action of group II and III mGlu receptor ligands and their role in inducing rap...

Call: OPUS 7 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

Instytut Farmakologii PAN

The role of chemokines in the pathogenesis of depression and molecular mechanism of action of antidepressants.

Call: OPUS 5 , Panel: NZ7

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii PAN

Research on influence of antidepressant drugs on serum and brain levels of neurotrophins in rats, affected by the time d...

Call: OPUS 4 , Panel: NZ4

Principal investigator: dr Maciej Sławomir Kuśmider

Instytut Farmakologii PAN

Electrochemical detection of phycotropic substances based on DNA intercalation

Call: PRELUDIUM 4 , Panel: ST4

Principal investigator: dr Joanna Maria Jankowska-Śliwińska

Instytut Biocybernetyki i Inżynierii Biomedycznej im. Macieja Nałęcza PAN

The role of CRH-BP protein in the regulation of the hypothalamic-pituitary-adrenal axis after antidepressant drugs treat...

Call: OPUS 3 , Panel: NZ4

Principal investigator: dr Joanna Solich

Instytut Farmakologii PAN

Role of the endocannabionoid system in the pathogenesis of depression and in the mechanism of action of antidepressant d...

Call: OPUS 3 , Panel: NZ7

Principal investigator: prof. Małgorzata Maria Filip

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny