Projects funded by the NCN


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198 projects found matching your search criteria :

  1. Identifying early biomarkers and molecular targets for therapeutic intervention in right ventricular dysfunction

    Call: OPUS 28 , Panel: NZ5

    Principal investigator: prof. Przemysław Błyszczuk

    Uniwersytet Jagielloński

  2. Molecular insights into NAD+ metabolism in Huntington's disease: role in pathophysiology and preclinical assessment of t...

    Call: OPUS 28 , Panel: NZ5

    Principal investigator: dr hab. Marta Urszula Tomczyk

    Gdański Uniwersytet Medyczny

  3. Porous bioglass-alginate composite granules as the antibiotic delivery system with therapeutic and regenerative potentia...

    Call: SONATA 20 , Panel: NZ7

    Principal investigator: dr Adrian Szewczyk

    Gdański Uniwersytet Medyczny

  4. A triple agonist of glucagon, GLP-1, and GIP receptors as a novel therapeutic option for the treatment of heart failure ...

    Call: SONATA 20 , Panel: NZ5

    Principal investigator: dr Marta Katarzyna Oknińska

    CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

  5. Selective autophagy-mediated protein degradation as a potential therapeutic strategy for the treatment of inflammatory c...

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: dr hab. Monika Emilia Marcinkowska

    Uniwersytet Jagielloński

  6. The H3K27M oncohistone-centred molecular mechanisms as therapeutic targets in pediatric malignant diffuse midline glioma...

    Call: SONATA BIS 14 , Panel: NZ3

    Principal investigator: dr Katarzyna Leszczyńska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  7. Exploring DMRTA2 in Glioblastoma: Epigenetic Regulation, Angiogenesis Disruption, and Biomarker Development

    Call: SONATA BIS 14 , Panel: NZ3

    Principal investigator: dr Marta Magdalena Maleszewska-Bobińska

    Uniwersytet Warszawski

  8. Improving the therapeutic potential of cytostatics through the use of abiotic metallacarboranes.

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Michalina Gos

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  9. Development of novel potential therapeutics in inflammatory bowel diseases based on nanoformulations employing senomodul...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: prof. Jakub Jerzy Fichna

    Uniwersytet Medyczny w Łodzi

  10. New phosphino derivatives of chinolone antibiotics and their complexes with copper (I) and copper (II) ions. Determinati...

    Call: OPUS 2 , Panel: ST5

    Principal investigator: prof. Małgorzata Janina Jeżowska-Bojczuk

    Uniwersytet Wrocławski, Wydział Chemii

  11. CD147 as a novel multifunctional modulator of podocyte metabolism and exosome biogenesis: Identification of new molecula...

    Call: OPUS 27 , Panel: NZ4

    Principal investigator: dr hab. Agnieszka Piwkowska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  12. ROS-Scavenging Magnetic Nanozymes with Remote Activation for Alzheimer Disease

    Call: M-ERA.NET 3 Call 2023 , Panel: NZ5

    Principal investigator: dr hab. Anna Ludwika Haduch

    Instytut Farmakologii PAN

  13. Is there an escape from antibioticresistant ESKAPE pathogens present in wastewater - the importance of last-chance antib...

    Call: SONATA 19 , Panel: NZ9

    Principal investigator: dr Katarzyna Natalia Grudlewska-Buda

    Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

  14. Modulation of protein interaction networks as a new therapeutic target in the treatment of hereditary retinal dystrophie...

    Call: SONATA 19 , Panel: NZ5

    Principal investigator: dr Xiaonan Liu

    Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

  15. Evaluation of the therapeutic potential of synthetic miRNA-223-3p analog in a rat model of severe asthma

    Call: SONATA 19 , Panel: NZ4

    Principal investigator: dr Wojciech Jerzy Langwiński

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  16. Actin cytoskeleton disorders as a pro-survival signaling activator and a therapeutic biomarker in Diffuse Large B-cell L...

    Call: SONATA BIS 13 , Panel: NZ5

    Principal investigator: dr Patryk Górniak

    Instytut Hematologii i Transfuzjologii

  17. Targeting IGH enhancer RNAs as a therapeutic approach in B-cell lymphoma

    Call: SONATA BIS 13 , Panel: NZ1

    Principal investigator: dr hab. Agnieszka Dzikiewicz-Krawczyk

    Instytut Genetyki Człowieka PAN

  18. Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej PAN

  19. Exploring the Therapeutic Effects of Human Adipose Tissue Mesenchymal Stem Cell (HATMSC) line Secretome on Chronic Skin ...

    Call: SONATA BIS 13 , Panel: NZ3

    Principal investigator: dr Honorata Kraśkiewicz

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  20. The inhibition of NMDAR and TRPM4 coupling - a hope for novel therapeutic target for the treatment of the ischemic brain...

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr Bartosz Sebastian Pomierny

    Uniwersytet Jagielloński, Collegium Medicum

  21. Three to tango - biomaterials with therapeutic and regenerative multifunctionality

    Call: SONATA BIS 13 , Panel: ST11

    Principal investigator: dr Marzena Krystyna Fandzloch

    Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego PAN

  22. Prioritizing diagnostics and therapeutics of human prion diseases through integrative omics

    Call: JPND Call 2023 , Panel: NZ2

    Principal investigator: prof. Beata Katarzyna Sikorska

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  23. Extensive analysis of the immunological profile of pediatric patients with acute lymphoblastic leukemia in order to iden...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Anna Krętowska-Grunwald

    Uniwersytet Medyczny w Białymstoku

  24. Cuproptosis, a novel pathway of regulated cell death as a therapeutic target in treatment-naïve and targeted therapy-res...

    Call: OPUS 25 , Panel: NZ5

    Principal investigator: dr hab. Mariusz Łukasz Hartman

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  25. Bigels with controlled release of hydrophilic and hydrophobic therapeutic compounds as potential dressings in the treatm...

    Call: OPUS 25 , Panel: ST11

    Principal investigator: dr hab. Monika Gosecka

    Centrum Badań Molekularnych i Makromolekularnych PAN

  26. Designing Active Inhibitors of SARS-CoV-2 Methyltransferases

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Alex Jun Matsuda

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  27. Targeting undruggable proteins involved in tumorigenesis – developing and characterization of advanced nanoplatform for ...

    Call: OPUS 25 , Panel: NZ6

    Principal investigator: dr hab. Monika Bzowska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Bitechnologii

  28. Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian b...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Bernadeta Angelika Pietrzak-Wawrzyńska

    Instytut Farmakologii PAN

  29. Therapeutic self-understanding

    Call: SONATA 18 , Panel: HS1

    Principal investigator: dr Jędrzej Piotr Grodniewicz

    Uniwersytet Jagielloński, Centrum Kopernika Badań Interdyscyplinarnych Uniwersytetu Jagiellońskiego

  30. Specific immune signatures of T cells as biomarkers of the post-COVID Syndrome and predictors of long-term health dysfun...

    Call: PRELUDIUM BIS 4 , Panel: NZ6

    Principal investigator: dr hab. Katarzyna Piwocka

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  31. Molecular insights into hypoxic tumors – for development of targeted cancer therapeutics

    Call: POLONEZ BIS 3 , Panel: NZ5

    Principal investigator: dr Marco Deiana

    Politechnika Wrocławska

  32. Computational deciphering of pro-ferroptotic cell death protein machinery as a fundamental step in the search for therap...

    Call: SONATA BIS 12 , Panel: ST4

    Principal investigator: dr hab. Karolina Anna Mikulska-Rumińska

    Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  33. Studies on the post-receptor mechanisms of TSPO in search of a novel therapeutic target of metabolic syndrome

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: dr Łukasz Kurach

    Uniwersytet Medyczny w Lublinie

  34. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Anna Szczepańska

    Instytut Farmakologii PAN

  35. Mechanisms and therapeutic potential of SGLT2/SGLT1 and NHE-1 inhibition in a rat model of heart failure with preserved ...

    Call: OPUS 23 , Panel: NZ5

    Principal investigator: dr hab. Urszula Mackiewicz

    CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

  36. Chemical and surgical castration of sex offenders - effective punishment, therapeutic measure or dehumanizing torture? A...

    Call: PRELUDIUM 21 , Panel: HS5

    Principal investigator: Katarzyna Teresa Jakubczak-Fopke

    Uniwersytet Gdański, Wydział Prawa i Administracji

  37. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Barbara Przepiórska-Drońska

    Instytut Farmakologii PAN

  38. The evaluation of therapeutic potential of β-caryophyllene in animal schizophrenia model - behavioral and molecular stud...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: dr Magdalena Białoń

    Instytut Farmakologii PAN

  39. Targeting of metabolic and transcriptomic cross-talk between leukemic cells and macrophages as a therapeutic strategy in...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Baran Natalia

    Instytut Hematologii i Transfuzjologii

  40. Mechanisms and consequences of CD19 loss in B-acute lymphoblastic leukaemia patients relapsing after CD19-CAR-T cell the...

    Call: PRELUDIUM BIS 3 , Panel: NZ5

    Principal investigator: prof. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  41. Targeting UDP-glucose and P2Y14 receptor interaction for therapeutic modulation of inflammatory lung diseases

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Tadeusz Piotr Karcz

    Uniwersytet Jagielloński, Collegium Medicum

  42. Role of RelA(p65) and cRel phosphorylations and their kinases in the biology of Diffuse-large B-cell lymphoma and Hodgki...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Maciej Stefan Szydłowski

    Instytut Hematologii i Transfuzjologii

  43. Inhibition of protein disulfide isomerases as a strategy for reduction of prothrombotic state in atherosclerosis; therap...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Kamil Przyborowski

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  44. Targeting of HSF1 as a therapeutic approach to inhibit the progression of hormone-dependent breast cancer.

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Natalia Vydra

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

  45. New immunomodulators of BTLA-HVEM complex as potential therapeutics in systemic lupus erythematosus

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Anna Wardowska

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  46. Identification and therapeutic targeting of the mRNA splicing alteration mechanisms driven by gain-of-function TP53 muta...

    Call: SONATA 17 , Panel: NZ5

    Principal investigator: dr Magdalena Oroń

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  47. Searching for new therapeutic targets in polyglutamine diseases

    Call: OPUS 22 , Panel: NZ2

    Principal investigator: prof. Marta Olejniczak

    Instytut Chemii Bioorganicznej PAN

  48. P-stereodefined phosphorothioate analogs of morpholino" oligonucleotides (sTMO) as a new model of therapeutic nucleic ac...

    Call: SONATA 17 , Panel: ST4

    Principal investigator: dr Katarzyna Jastrzębska

    Centrum Badań Molekularnych i Makromolekularnych PAN

  49. Non-provitamin A carotenoids as a novel therapeutic strategy in intestinal failure associated liver disease (IFALD)

    Call: PRELUDIUM BIS 3 , Panel: NZ7

    Principal investigator: dr hab. Maciej Jan Stawny

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  50. efFect of nanoscale, three dimensIonal arrangement of proteins on biological and Therapeutic activity (FIT)

    Call: OPUS 22 (LAP) , Panel: NZ1

    Principal investigator: dr Antonina Naskalska

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego