Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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P-stereodefined phosphorothioate analogs of 'morpholino" oligonucleotides (sTMO) as a new model of therapeutic nucleic acids: synthesis, structure, physicochemical and biological properties.

2021/43/D/ST4/02433

Keywords:

antisense oligonucleotides morpholino analogs P-stereodefined phosphorothioate analogs oxathiaphospholane approach thermodynamic stability

Descriptors:

  • ST4_9: Biological chemistry
  • ST4_8: Organic chemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Katarzyna Jastrzębska 

Number of co-investigators in the project: 4

Call: SONATA 17 - announced on 2021-09-15

Amount awarded: 1 223 800 PLN

Project start date (Y-m-d): 2022-07-11

Project end date (Y-m-d): 2025-07-10

Project duration:: 36 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.