Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Modulation of immune cells activity in the tumor microenvironment by oligonucleotide therapeutics delivered by silk nanocarriers.

2020/37/B/NZ6/03435

Keywords:

immunotherapy cancer tumor microenvironment STAT3 oligonucleotide therapeutics silk nanocarriers trageted drug delivery

Descriptors:

  • NZ6_008:
  • NZ6_001:
  • NZ5_007:

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Hanna Dams-Kozłowska 

Number of co-investigators in the project: 7

Call: OPUS 19 - announced on 2020-03-16

Amount awarded: 2 196 000 PLN

Project start date (Y-m-d): 2021-03-01

Project end date (Y-m-d): 2026-02-28

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (6)
  1. Oligonucleotide-Based Therapeutics for STAT3 Targeting in Cancer-Drug Carriers Matter
    Authors:
    Sara Molenda, Agata Sikorska, Anna Florczak, Patryk Lorenc, Hanna Dams-Kozlowska
    Academic press:
    Cancers (rok: 2023, tom: 15, strony: 5647), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers15235647 - link to the publication
  2. Systemic and Local Silk-Based Drug Delivery Systems for Cancer Therapy
    Authors:
    Anna Florczak, Tomasz Deptuch, Kamil Kucharczyk, Hanna Dams-Kozlowska
    Academic press:
    Cancers (rok: 2021, tom: 13, strony: 5389), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13215389 - link to the publication
  3. In vivo study of the immune response to bioengineered spider silk spheres
    Authors:
    Tomasz Deptuch, Karolina Penderecka, Mariusz Kaczmarek, Sara Molenda, Hanna Dams‑Kozlowska
    Academic press:
    Scientific Reports (rok: 2022, tom: 12, strony: 13480), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-022-17637-7 - link to the publication
  4. Systemic and Local Silk-Based Drug Delivery Systems for Cancer Therapy
    Authors:
    Anna Florczak, Tomasz Deptuch, Kamil Kucharczyk, Hanna Dams-Kozlowska
    Academic press:
    Cancers (rok: 2021, tom: 13, strony: 5389), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13215389 - link to the publication
  5. In vivo study of the immune response to bioengineered spider silk spheres
    Authors:
    Tomasz Deptuch, Karolina Penderecka, Mariusz Kaczmarek, Sara Molenda, Hanna Dams‑Kozlowska
    Academic press:
    Scientific Reports (rok: 2022, tom: 12, strony: 13480), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-022-17637-7 - link to the publication
  6. Systemic and Local Silk-Based Drug Delivery Systems for Cancer Therapy
    Authors:
    Anna Florczak, Tomasz Deptuch, Kamil Kucharczyk, Hanna Dams-Kozlowska
    Academic press:
    Cancers (rok: 2021, tom: 13, strony: 5389), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13215389 - link to the publication