Modulation of immune cells activity in the tumor microenvironment by oligonucleotide therapeutics delivered by silk nanocarriers.
2020/37/B/NZ6/03435
Keywords
Descriptors
- NZ6_008: Inne zagadnienia pokrewne
- NZ6_001: Odporność swoista i nieswoista
- NZ5_007: Leczenie chorób człowieka
Panel
NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution
Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu
Voivodeship: wielkopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 7
Call
OPUS 19 – announced on 2020-03-16
- Amount awarded
- 2 196 000 PLN
- Project start date
- 2021-03-01
- Project end date
- 2027-02-28
- Project duration
- 72 months (the same as in the proposal)
- Project status
- Pending project
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (4)
-
Oligonucleotide-Based Therapeutics for STAT3 Targeting in Cancer-Drug Carriers Matter
- Authors:
- Sara Molenda, Agata Sikorska, Anna Florczak, Patryk Lorenc, Hanna Dams-Kozlowska
- Academic press:
- Cancers (year: 2023, volume: 15, pages: 5647), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/cancers15235647 – link to the publication
-
Developing the Strategy to Use Silk Spheres for Efficient, Targeted Delivery of Oligonucleotide Therapeutics to Cancer Cells
- Authors:
- Sara Molenda, Tomasz Deptuch, Agata Sikorska, Patryk Lorenc, Maciej Jerzy Smialek, Anna Florczak-Substyk, Piotr Pawlak, Hanna Dams-Kozlowska
- Academic press:
- Int J Nanomedicine (year: 2025, volume: 20, pages: 8023-8039), Publisher: Dove Medical Press/Taylor & Francis Group
- Status:
- Published
- DOI:
- 10.2147/IJN.S519906 – link to the publication
-
Systemic and Local Silk-Based Drug Delivery Systems for Cancer Therapy
- Authors:
- Anna Florczak, Tomasz Deptuch, Kamil Kucharczyk, Hanna Dams-Kozlowska
- Academic press:
- Cancers (year: 2021, volume: 13, pages: 5389), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/cancers13215389 – link to the publication
-
In vivo study of the immune response to bioengineered spider silk spheres
- Authors:
- Tomasz Deptuch, Karolina Penderecka, Mariusz Kaczmarek, Sara Molenda, Hanna Dams‑Kozlowska
- Academic press:
- Scientific Reports (year: 2022, volume: 12, pages: 13480), Publisher: Springer Nature
- Status:
- Published
- DOI:
- 10.1038/s41598-022-17637-7 – link to the publication