Projects funded by the NCN
The roles and therapeutic potential of distinct dystrophin and utrophin isoforms in the central and peripheral nervous system
2021/43/B/NZ5/00723
Keywords:
Duchenne muscular dystrophy (DMD) dystrophin utrophin recombinant adeno-associated viral (rAAV) vectors central nervous system peripheral nervous system neurons astrocytes oligodendrocytes microglia Schwann cells
Descriptors:
- NZ5_003:
- NZ5_007:
Panel:
NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution :
Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii
woj. wielkopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 5
Call: OPUS 22 - announced on 2021-09-15
Amount awarded: 2 533 452 PLN
Project start date (Y-m-d): 2022-10-03
Project end date (Y-m-d): 2027-10-02
Project duration:: 60 months (the same as in the proposal)
Project status: Pending project
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- Systemic Treatment of Body-Wide Duchenne Muscular Dystrophy SymptomsAuthors:Patryk KoniecznyAcademic press:Clinical Pharmacology and Therapeutics (rok: 2024, tom: 116, strony: 1472-1484), Wydawca: Wiley-BlackwellStatus:PublishedDOI:10.1002/cpt.3363 - link to the publication
- Dystrophin- and Utrophin-Based Therapeutic Approaches for Treatment of Duchenne Muscular Dystrophy: A Comparative ReviewAuthors:Sylwia Szwec, Zuzanna Kapłucha, Jeffrey S. Chamberlain, Patryk KoniecznyAcademic press:BioDrugs (rok: 2024, tom: 38, strony: 95-119), Wydawca: ADIS INT LTDStatus:PublishedDOI:10.1007/s40259-023-00632-3 - link to the publication