Mechanism of splicing of MBNL1 transcript and its implications for potential therapeutic strategies for myotonic dystrophy.

2020/39/D/NZ3/01658

Keywords

Descriptors

  • NZ3_001: Biologia komórki
  • NZ1_001: Biologia molekularna
  • NZ5_007: Leczenie chorób człowieka

Panel

NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Katarzyna Magdalena Taylor

Number of co-investigators in the project: 3

Call

SONATA 16 – announced on 2020-09-15

Amount awarded
1 538 380 PLN
Project start date
2021-07-15
Project end date
2026-07-14
Project duration
60 months (the same as in the proposal)
Project status
Pending project

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (1)

  1. Modulatory role of RNA helicases in MBNL-dependent alternative splicing regulation

    Authors:
    Taylor Katarzyna, Piasecka Agnieszka, Kajdasz Arkadiusz, Brzęk Aleksandra, Espinoza Micaela Polay, Bourgeois Cyril F., Jankowski Artur, Borowiak Małgorzata, Raczyńska Katarzyna D., Sznajder Łukasz J., Sobczak Krzysztof
    Academic press:
    Cellular and Molecular Life Sciences (year: 2023, volume: 11, pages: 335), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s00018-023-04927-0 – link to the publication

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