Projects funded by the NCN


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137 projects found matching your search criteria :

  1. Strategy to overcome the "ionic checkpoint" and improve the antitumor immunotherapy.

    Call: OPUS 29 , Panel: NZ7

    Principal investigator: dr Beata Pyrzyńska

    Warszawski Uniwersytet Medyczny

  2. LLT1 as a regulator of the immune response and a dual-target immunotherapy approach in colorectal cancer directed at NK ...

    Call: OPUS 29 , Panel: NZ6

    Principal investigator: dr Marzena Dorota Lenart

    Uniwersytet Jagielloński

  3. Advanced High-Throughput Microfluidic Platform for Engineered T-Cell Screening

    Call: SONATINA 9 , Panel: NZ7

    Principal investigator: dr Alicja Andrea Przybyszewska-Podstawka

    Uniwersytet Warszawski

  4. Doping Mott Insulators: Band Electrons, Spin Polarons or Fractional Excitations?

    Call: OPUS 28 , Panel: ST3

    Principal investigator: dr hab. Krzysztof Wohlfeld

    Uniwersytet Warszawski

  5. Adopted orphan nuclear receptors as new regulators of testis immune privilege

    Call: SONATA 20 , Panel: NZ3

    Principal investigator: dr Alicja Kinga Kamińska

    Uniwersytet Jagielloński

  6. T-cell exhaustion factors related to primary hepatocellular carcinoma development of the hepatitis C virus etiology

    Call: SONATA BIS 14 , Panel: NZ6

    Principal investigator: dr hab. Kamila Anna Cortés-Fendorf

    Warszawski Uniwersytet Medyczny

  7. Immune response in ischemic stroke: T and B cells: friends or foes? A new paradigm for immune regulation

    Call: PRELUDIUM 23 , Panel: NZ4

    Principal investigator: Anna Mirończuk

    Uniwersytet Medyczny w Białymstoku

  8. Uncovering the NK cell-dependent mechanisms of action of daratumumab in T-ALL

    Call: PRELUDIUM 23 , Panel: NZ3

    Principal investigator: Karolina Maria Bełdzińska-Gądek

    Gdański Uniwersytet Medyczny

  9. Identification of circulating biomarkers for monitoring anti-CD19 CAR-T cell treatment response in patients with aggress...

    Call: PRELUDIUM 23 , Panel: NZ5

    Principal investigator: Monika Szelest

    Uniwersytet Medyczny w Lublinie

  10. Mitochondrial metabolism of glycerol as a regulator of lymphocyte homeostasis and pathology

    Call: OPUS 27 , Panel: NZ6

    Principal investigator: dr Marcin Kaminski

    Politechnika Śląska

  11. Identification and characterization of omics profiles in patients' serum during anti-CD19 CAR-T cell therapy

    Call: PRELUDIUM 23 , Panel: NZ5

    Principal investigator: Jaromir Bartosz Tomasik

    Warszawski Uniwersytet Medyczny

  12. Zn2+-dependent competition between CD4 and CD8α coreceprtor for Lck tyrosine kinase

    Call: SONATA 19 , Panel: NZ1

    Principal investigator: dr Anna Marta Kocyła

    Uniwersytet Wrocławski, Wydział Biotechnologii

  13. Transparency – important morphological trait for qualitative assessment of marine particles and plankton (T-trait)

    Call: OPUS 26 , Panel: ST10

    Principal investigator: dr hab. Emilia Małgorzata Trudnowska

    Instytut Oceanologii PAN

  14. CAR(dio)-T(oxicity)- Engineered Heart Tissue model for CAR-T cardiotoxicity evaluation

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Agnieszka Joanna Zimna

    Instytut Genetyki Człowieka PAN

  15. Early to middle Paleozoic evolution of the >3000 km paleo-margins of the southern Central Asian Orogenic Belt: Implicati...

    Call: SONATA 19 , Panel: ST10

    Principal investigator: dr Jérémie Maurice Georges Soldner

    Instytut Nauk Geologicznych, Polska Akademia Nauk, Ośrodek Badawczy w Krakowie

  16. Modulation of the N-glycosylation as a tool to improve the CAR-T immunotherapy efficacy

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr Agnieszka Graczyk-Jarzynka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  17. From Three T(w)o One dye: the innovative materials for white and multicolor emission

    Call: SONATA 19 , Panel: ST5

    Principal investigator: dr Alina Barbara Szukalska

    Politechnika Wrocławska

  18. Exploring kinase hyperactivation as an innovative approach for chemo-immunotherapy for B cell acute lymphoblastic leukem...

    Call: PRELUDIUM BIS 5 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  19. Searching for novel regulators of antitumor immune response

    Call: MAESTRO 15 , Panel: NZ6

    Principal investigator: dr hab. Magdalena Hanna Winiarska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  20. Unraveling protease activation in stimulated CAR-T cells to identify new biomarkers for assessing their clinical efficac...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  21. Heterogeneity immunocompetent cells during chimeric antigen receptor T cell (CAR-T) CD19 immunotherapy.

    Call: PRELUDIUM 22 , Panel: NZ6

    Principal investigator: Aleksandra Maria Oszer

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  22. Polarized Raman spectroscopy and diffraction studies of hydrated minerals with layered and microporous structures: metho...

    Call: PRELUDIUM 22 , Panel: ST10

    Principal investigator: Katarzyna Maria Skrzyńska

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

  23. Overcoming CAR-T cell exhaustion via CRISPR- based enhancer modification

    Call: PRELUDIUM 22 , Panel: NZ6

    Principal investigator: dr Karolina Rassek

    Instytut Genetyki Człowieka PAN

  24. Functional consequences of loss of chromosome Y (LOY) in immune cells in the context of cancer - ex vivo and in vitro st...

    Call: OPUS 25 , Panel: NZ2

    Principal investigator: dr Jan Dumański

    Gdański Uniwersytet Medyczny, Międzynarodowa Agenda Badawcza

  25. Multiparameter analysis of co-inhibitory and co-stimulatory immune checkpoints and their role in the induction of immuno...

    Call: PRELUDIUM 22 , Panel: NZ6

    Principal investigator: dr Dorota Suszczyk

    Uniwersytet Medyczny w Lublinie

  26. Efektywność nowatorskiej terapii inhibitorami JAK u pacjentów z reumatoidalnym zapaleniem stawów w odniesieniu do profil...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Sylwia Anna Biały

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  27. Overcoming CAR-T cell exhaustion by optogenetic regulation

    Call: PRELUDIUM 22 , Panel: NZ3

    Principal investigator: dr Alicja Andrea Przybyszewska-Podstawka

    Uniwersytet Medyczny w Lublinie

  28. Unveiling the molecular signature underlying resistance to CD19 CAR-T therapy in malignant cells.

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Marta Krawczyk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  29. Potential of TH cell profiling in personalized multiple sclerosis treatmentplanning.

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Donskow-Łysoniewska

    Uczelnia Łazarskiego

  30. Specific immune signatures of T cells as biomarkers of the post-COVID Syndrome and predictors of long-term health dysfun...

    Call: PRELUDIUM BIS 4 , Panel: NZ6

    Principal investigator: dr hab. Katarzyna Piwocka

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  31. Role of TRPA1 and TRPM2 ion channels in the regulation of T cell physiology and metabolism in response to hypoxia

    Call: SONATA 18 , Panel: NZ6

    Principal investigator: dr Joanna Katarzyna Bujak

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

  32. Hybrid materials responsive to external stimuli for local drug delivery in endometriosis treatment - analysis of selecte...

    Call: SONATA 18 , Panel: ST5

    Principal investigator: dr Olga Urbanek-Świderska

    Instytut Podstawowych Problemów Techniki Polska Akademia Nauk

  33. Unraveling genes and mechanisms underlying relapse of T-cell acute lymphoblastic leukemia

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: dr hab. Małgorzata Agnieszka Dawidowska

    Instytut Genetyki Człowieka PAN

  34. T-shaped antler axes in the Mesolithic and Neolithic of the Central European Lowland

    Call: PRELUDIUM BIS 4 , Panel: HS3

    Principal investigator: prof. Jacek Kabaciński

    Instytut Archeologii i Etnologii Polskiej Akademii Nauk

  35. Depletion of the tumor microenvironment as a novel strategy potentiating the efficacy of immunotherapies.

    Call: OPUS 23 , Panel: NZ6

    Principal investigator: dr Małgorzata Agnieszka Bajor

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  36. Algebraic spectral gaps in group cohomology

    Call: SONATINA 6 , Panel: ST1

    Principal investigator: dr Piotr Mizerka

    Instytut Matematyczny Polskiej Akademii Nauk

  37. Mechanisms and consequences of CD19 loss in B-acute lymphoblastic leukaemia patients relapsing after CD19-CAR-T cell the...

    Call: PRELUDIUM BIS 3 , Panel: NZ5

    Principal investigator: prof. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  38. The quantity and functional state of γδT lymphocytes in adult patients with primary immunodeficiencies (PIDs) especially...

    Call: PRELUDIUM BIS 3 , Panel: NZ6

    Principal investigator: prof. Jacek Mariusz Roliński

    Uniwersytet Medyczny w Lublinie

  39. Petrochronology of the northeastern Gondwana terranes: implications for the supercontinent cycle.

    Call: POLONEZ BIS 1 , Panel: ST10

    Principal investigator: dr Soldner Maurice Georges Jérémie

    Instytut Nauk Geologicznych, Polska Akademia Nauk, Ośrodek Badawczy w Krakowie

  40. Laser Emission of Thioflavin T and its analogues to uncover the early symptoms of neurodegenerative diseases.

    Call: SONATA 17 , Panel: ST4

    Principal investigator: dr Piotr Hańczyc

    Uniwersytet Warszawski, Wydział Fizyki

  41. Regulation of SLPI-IL-17 signaling pathway during respiratory infections and vaccination.

    Call: POLONEZ BIS 1 , Panel: NZ6

    Principal investigator: dr Mieszko Wilk

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  42. The evolution of non-classical MHC class I genes and T-cell receptor repertoires in salamanders

    Call: OPUS 22 , Panel: NZ8

    Principal investigator: prof. Wiesław Babik

    Uniwersytet Jagielloński, Wydział Biologii

  43. Duality Symmetries as Key to Quantum Spacetime

    Call: SONATA BIS 11 , Panel: ST2

    Principal investigator: dr Falk Hassler

    Uniwersytet Wrocławski, Wydział Fizyki i Astronomii

  44. Analysis on groups

    Call: MAESTRO 13 , Panel: ST1

    Principal investigator: dr hab. Piotr Wojciech Nowak

    Instytut Matematyczny Polskiej Akademii Nauk

  45. Thymus involution rate and lifespan in the animal model with low or high basal metabolism (BMR)

    Call: PRELUDIUM 20 , Panel: NZ8

    Principal investigator: dr Sylwia Buczyńska

    Uniwersytet w Białymstoku, Wydział Biologii

  46. Functional divergence of Flowering Locus T gene duplicates in photoperiod and vernalization control of flowering inducti...

    Call: OPUS 21 , Panel: NZ9

    Principal investigator: dr hab. Michał Piotr Książkiewicz

    Instytut Genetyki Roślin PAN

  47. Investigation of exotic helium isotopes by means of 6He(d,t)5He reaction

    Call: PRELUDIUM 20 , Panel: ST2

    Principal investigator: Bogumił Zbigniew Zalewski

    Uniwersytet Warszawski, Środowiskowe Laboratorium Ciężkich Jonów

  48. Identification of mTOR pathway deregulation mechanisms alternative to mutations in T-cell acute lymphoblastic leukemia (...

    Call: PRELUDIUM 20 , Panel: NZ2

    Principal investigator: Natalia Maćkowska-Maślak

    Instytut Genetyki Człowieka PAN

  49. Identification of surface proteins as alternate targets for CAR-T therapy against CD19-negative tumors.

    Call: PRELUDIUM BIS 2 , Panel: NZ6

    Principal investigator: dr hab. Magdalena Hanna Winiarska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  50. Non-canonical RNA tailing and other post-transcriptional regulatory mechanisms in T cell-mediated adaptive immunity.

    Call: SONATA BIS 10 , Panel: NZ2

    Principal investigator: dr hab. Seweryn Mroczek

    Uniwersytet Warszawski, Wydział Biologii