Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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New approaches to characterize Th17/Treg cell balance contributing to anti-tumour immune responses

2018/30/Q/NZ6/00769

Keywords:

T helper 17 cell Regulatory T cell colorectal cancer systems biology cancer immunotherapy

Descriptors:

  • NZ6_2: Clinical immunology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Zhi Chen 

Number of co-investigators in the project: 6

Call: SHENG 1 - announced on 2018-06-15

Amount awarded: 2 743 764 PLN

Project start date (Y-m-d): 2019-10-31

Project end date (Y-m-d): 2024-10-30

Project duration:: 36 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Proteomics approaches to characterize the immune responses in cancer
    Authors:
    Víctor Urbiola-Salvador, Dominika Miroszewska, Agnieszka Jabłońska, Talha Qureshi, Zhi Chen
    Academic press:
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (rok: 2022, tom: 1869(8), strony: 119266), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2022.119266 - link to the publication
  2. Animal unit hygienic conditions influence mouse intestinal microbiota and contribute to T-cell-mediated colitis
    Authors:
    Mariana Cázares-Olivera, Dominika Miroszewska, Lili Hu, Jacek Kowalski, Ulla-Marjut Jaakkola, Seppo Salminen, Bin Li, Emrah Yatkin, Zhi Chen
    Academic press:
    Experimental Biology and Medicine (Maywood) (rok: 2022, tom: 247(19), strony: 1752-1763), Wydawca: SAGE
    Status:
    Published
    DOI:
    10.1177/15353702221113826 - link to the publication
  3. Plasma protein changes reflect colorectal cancer development and associated inflammation
    Authors:
    Víctor Urbiola-Salvador, Agnieszka Jabłońska, Dominika Miroszewska, Qianru Huang, Katarzyna Duzowska, Kinga Drężek-Chyła, Marek Zdrenka, Ewa Śrutek, Łukasz Szylberg, Michał Jankowski, Dariusz Bała, Wojciech Zegarski, Tomasz Nowikiewicz, Wojciech Makarewicz, Agnieszka Adamczyk, Aleksandra Ambicka, Marcin Przewoźnik, Agnieszka Harazin-Lechowicz, Janusz Ryś, Natalia Filipowicz, Arkadiusz Piotrowski, Jan P. Dumanski, Bin Li, Zhi Chen
    Academic press:
    Frontiers in Oncology (rok: 2023, tom: 13, strony: 1158261), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fonc.2023.1158261 - link to the publication
  4. The effects of post-translational modifications on Th17/Treg cell differentiation
    Authors:
    Gwenaëlle Le Menn, Agnieszka Jabłońska, Zhi Chen
    Academic press:
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (rok: 2022, tom: 1869(6), strony: 119223), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2022.119223 - link to the publication

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