Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of NFAT (nuclear factor of activated T cells) and GM-CSF (granulocyte/macrophage colony stimulating factor) signaling in glioma pathogenesis

2014/15/B/NZ3/04704

Keywords:

glioma pathobiology microglia cytokine signaling GM-CSF transcription regulation NFAT

Descriptors:

  • NZ3_5: Molecular neurobiology
  • NZ3_7: Signal transduction
  • NZ4_4: Pathophysiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Aleksandra Ellert-Miklaszewska 

Number of co-investigators in the project: 5

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 690 000 PLN

Project start date (Y-m-d): 2015-08-11

Project end date (Y-m-d): 2019-08-10

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Czytnik płytek do pomiaru absorbancji, fluorescencji i luminescencji (90 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Molecular interactions between tumor and its microenvironment in malignant gliomas
    Authors:
    Ellert-Miklaszewska Aleksandra, Pasierbinska Maria, Poleszak Katarzyna, Kaminska Bozena
    Academic press:
    Postępy Biochemii (rok: 2018, tom: 64, strony: 129 - 140), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    10.18388/pb.2018_123 - link to the publication
  2. Tumour-derived CSF2/granulocyte macrophage colony stimulating factor controls myeloid cell accumulation and progression of gliomas
    Authors:
    Malgorzata Sielska, Piotr Przanowski, Maria Pasierbińska, Kamil Wojnicki, Katarzyna Poleszak, Bartosz Wojtas, Dominika Grzeganek, Aleksandra Ellert-Miklaszewska, Min-Chi Ku, Helmut Kettenmann, Bozena Kaminska
    Academic press:
    British Jounal of Cancer (rok: 2020, tom: 123, strony: 438-448), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41416-020-0862-2 - link to the publication
  3. Delivery of the VIVIT Peptide to Human Glioma Cells to Interfere with Calcineurin-NFAT Signaling
    Authors:
    Aleksandra Ellert-Miklaszewska, Agata Szymczyk, Katarzyna Poleszak, Bozena Kaminska
    Academic press:
    Molecules (rok: 2021, tom: 26, strony: 45306), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules26164785 - link to the publication
  4. Short peptides interfering with signaling pathways as new therapeutic tools for cancer treatment
    Authors:
    Aleksandra Ellert-Miklaszewska, Katarzyna Poleszak, Bozena Kaminska
    Academic press:
    Future Medicinal Chemistry (rok: 2017, tom: 9(2), strony: 199-221), Wydawca: Future Science
    Status:
    Published
    DOI:
    10.4155/fmc-2016-0189 - link to the publication

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