Projects funded by the NCN

Design and Pharmacological Evaluation of Marine Alkaloid-Inspired 5-HT2A Receptor Ligands

Call: PRELUDIUM 24 , Panel: NZ1

Principal investigator: Szymon Kazimierz Kordylewski

Instytut Farmakologii PAN

NMR Spectroscopy as Molecular Language: A Deep Learning Approach to Bioactivity Prediction

Call: PRELUDIUM 24 , Panel: NZ7

Principal investigator: Arkadiusz Bogumił Leniak

Instytut Farmakologii PAN

Design, synthesis and catalytic activity studies of heterometallic rare-earth complexes in the synthesis of polymer anti...

Call: PRELUDIUM 23 , Panel: ST4

Principal investigator: Adrian Krzysztof Kowaliński

Politechnika Wrocławska

Impact of Composition and Cooling Rate on Mechanical Properties of High Entropy Metallic Glasses

Call: SONATA BIS 13 , Panel: ST3

Principal investigator: dr Silvia Bonfanti

Narodowe Centrum Badań Jądrowych

"I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr...

Call: OPUS 25 , Panel: NZ7

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii PAN

Designing Active Inhibitors of SARS-CoV-2 Methyltransferases

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Alex Jun Matsuda

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Decrypting the "sulfation code" of glycosaminoglycans for understanding their function in the extracellular matrix

Call: OPUS 25 , Panel: ST4

Principal investigator: dr hab. Sergey Samsonov

Uniwersytet Gdański, Wydział Chemii

Design of multidentate surface bonding groups as a strategy for controllingstability and conductivity of organic monolay...

Call: OPUS 24 , Panel: ST5

Principal investigator: prof. Piotr Cyganik

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Computational deciphering of pro-ferroptotic cell death protein machinery as a fundamental step in the search for therap...

Call: SONATA BIS 12 , Panel: ST4

Principal investigator: dr hab. Karolina Anna Mikulska-Rumińska

Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Analysis of thermal processes and degradation mechanisms of long wavelength, 10-16um, quantum cascade lasers. Optimizati...

Call: SONATA BIS 11 , Panel: ST7

Principal investigator: dr Dorota Iwona Pierścińska

Sieć Badawcza ŁUKASIEWICZ - Instytut Mikroelektroniki i Fotoniki

True Bioisosteres - Structural and Thermodynamic Classification of Molecular Fragments for Ligand Design

Call: SONATA BIS 11 , Panel: ST4

Principal investigator: dr Maura Dagmara Malińska

Uniwersytet Warszawski, Wydział Chemii

Assembly-by-Design: Polyhedral metal complexes as molecular building blocks of functional supramolecular assemblies (Fun...

Call: OPUS 21 , Panel: ST4

Principal investigator: prof. Janusz Zbigniew Lewiński

Politechnika Warszawska, Wydział Chemiczny

IoCarboNanoFluids (ICON Fluids) as a novel class of properties-by-design carbon nanotubes-functionalized multi-ionic sys...

Call: OPUS 21 , Panel: ST5

Principal investigator: prof. Sławomir Boncel

Politechnika Śląska, Wydział Chemiczny

Stop the biting: tracking the insecticide-mediated allosteric changes in voltage-gated sodium channels and design of sel...

Call: PRELUDIUM 20 , Panel: NZ3

Principal investigator: dr Beata Niklas

Uniwersytet Mikołaja Kopernika, Wydział Nauk Biologicznych i Weterynaryjnych

Design of metal-peptide complexes based on amyloid β sequence with a His-2 binding motif as selective receptors in elect...

Call: PRELUDIUM 20 , Panel: ST4

Principal investigator: Aleksandra Magdalena Tobolska

Politechnika Warszawska

Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

Call: OPUS 21 , Panel: NZ7

Principal investigator: prof. Sylwia Anna Rodziewicz-Motowidło

Uniwersytet Gdański, Wydział Chemii

Towards the integrated molecular modelling – machine learning (MM-ML)" computational method for supporting the design of...

Call: SHENG 2 , Panel: ST5

Principal investigator: prof. Tomasz Puzyn

Uniwersytet Gdański, Wydział Chemii

Self-learning systems in the design of compounds modulating GPCR receptors activation.

Call: OPUS 20 , Panel: NZ2

Principal investigator: dr hab. Dorota Latek

Uniwersytet Warszawski, Wydział Chemii

Blocking HVEM/LIGHT interactions using peptides - an innovative approach to immunosuppression

Call: PRELUDIUM BIS 2 , Panel: ST4

Principal investigator: dr hab. Adam Kazimierz Sieradzan

Uniwersytet Gdański, Wydział Chemii

Design of Functional Organic Memristors (DOOM)

Call: OPUS 20 , Panel: ST4

Principal investigator: dr hab. Cina Foroutannejad

Instytut Chemii Organicznej Polska Akademia Nauk

Design of high selective and safe juvenile hormone epoxide hydrolases inhibitors targeting selected pests based on the c...

Call: OPUS 20 , Panel: ST4

Principal investigator: dr hab. Artur Wiktor Góra

Politechnika Śląska, Centrum Biotechnologii

Ionic conductors based on cyanido coordination architectures: design and functionalization

Call: SONATA 16 , Panel: ST5

Principal investigator: dr Mateusz Piotr Reczyński

Uniwersytet Jagielloński, Wydział Chemii

To what extent the transcriptomic response in the events initiating lung toxicity in mice depends on the structural feat...

Call: OPUS 19 , Panel: ST5

Principal investigator: prof. Tomasz Puzyn

Uniwersytet Gdański, Wydział Chemii

Combination of Molecular Simulation and Deep Learning for De Novo Drug Design

Call: PRELUDIUM 19 , Panel: ST6

Principal investigator: dr Tomasz Jakub Danel

Uniwersytet Jagielloński, Wydział Matematyki i Informatyki

Chiral molecular magnets - control of the UV-vis light absorption using magnetic field

Call: OPUS 19 , Panel: ST5

Principal investigator: dr hab. Dawid Pinkowicz

Uniwersytet Jagielloński, Wydział Chemii

New photochromic molecules for the construction of photoswitchable molecular magnets

Call: PRELUDIUM BIS 1 , Panel: ST5

Principal investigator: dr hab. Dawid Pinkowicz

Uniwersytet Jagielloński, Wydział Chemii

New designs of long-wavelength quantum cascade lasers on InP substrates

Call: SONATA 15 , Panel: ST7

Principal investigator: dr Piotr Gutowski

Sieć Badawcza ŁUKASIEWICZ - Instytut Mikroelektroniki i Fotoniki

Molecular mechanisms, signal transduction and inhibition of PEBP1-15LOX protein complex triggering the ferroptotic cell ...

Call: SONATA 15 , Panel: ST4

Principal investigator: dr hab. Karolina Anna Mikulska-Rumińska

Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Exploring the sequence-structure relationship as a starting point for the design of DNA G-quadruplexes with a given topo...

Call: OPUS 18 , Panel: ST4

Principal investigator: dr hab. Jacek Czub

Politechnika Gdańska

Design of photoswitchable dismantlers of biomaterials made of amyloid fibrils.

Call: OPUS 16 , Panel: ST4

Principal investigator: dr Dorota Anna Niedziałek

Instytut Biochemii i Biofizyki PAN

Molecular design of polymers with unique physical properties

Call: SONATA BIS 8 , Panel: ST3

Principal investigator: dr hab. Jarosław Paturej

UNIWERSYTET ŚLĄSKI, Wydział Nauk Ścisłych i Technicznych

Modeling phosphorylation by human thymidine kinase 1. A crucial step in the rational design of thymidine-analogue radios...

Call: PRELUDIUM 15 , Panel: ST4

Principal investigator: dr Samanta Kinga Romanowska

Uniwersytet Gdański, Wydział Chemii

Design and preparation of heterometallic molecular clusters. Studies of their catalytic properties and transformation to...

Call: OPUS 15 , Panel: ST5

Principal investigator: prof. Piotr Ludwik Sobota

Politechnika Wrocławska

Design and optimisation of molecular interface for efficient electron transfer within photosystem I-based photovoltaic d...

Call: OPUS 14 , Panel: ST5

Principal investigator: dr hab. Joanna Monika Kargul

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Small-molecular chemical probes impairing Spire/FMN2 interaction as tools for the deconvolution of the role of the compl...

Call: PRELUDIUM 14 , Panel: ST5

Principal investigator: Radosław Dariusz Kitel

Uniwersytet Jagielloński, Wydział Chemii

Molecular picture of the mechanochemical coupling in ATP synthase as a conceptual framework for the development of novel...

Call: SONATA BIS 7 , Panel: NZ2

Principal investigator: dr hab. Jacek Czub

Politechnika Gdańska, Wydział Chemiczny

Developement of new methods for designing RNA molecules that fold into desired spatial structures and their use for deve...

Call: OPUS 13 , Panel: NZ2

Principal investigator: prof. Janusz Marek Bujnicki

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Design of new small molecular regulators (inhibitors, activators) of the catalytic activity of adenylate kinases. Molecu...

Call: OPUS 13 , Panel: ST4

Principal investigator: dr Anna Kozakiewicz-Piekarz

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Modeling of quantitative structure-metabolic stability relationships as a tool to improve design of potential novel anti...

Call: OPUS 12 , Panel: NZ7

Principal investigator: prof. Tomasz Bączek

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Computer-aided molecular design of ionic liquids using new QSPR models based on different dimensionalities of chemical r...

Call: SONATA 12 , Panel: ST4

Principal investigator: dr Kamil Paduszyński

Politechnika Warszawska, Wydział Chemiczny

Rational design of molecular nanomagnets: synthesis, characterization, theoretical description and computational modelin...

Call: OPUS 11 , Panel: ST4

Principal investigator: prof. Czesław Zygmunt Rudowicz

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Design and validation of multi-gene transcriptional signature as molecular diagnostic tool in paediatric brain tumours

Call: OPUS 11 , Panel: NZ2

Principal investigator: dr hab. Maria Anna Łastowska

INSTYTUT - POMNIK - CENTRUM ZDROWIA DZIECKA

Design of hybrid methods of structure modification and innovative protective layers manufacturing ensuring chemical stab...

Call: OPUS 11 , Panel: ST8

Principal investigator: dr hab. Andrzej Koleżyński

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Inżynierii Materiałowej i Ceramiki

Towards an efficient design of biosensors: an investigation of the interplay between light harvesting proteins and graph...

Call: POLONEZ 1 , Panel: ST4

Principal investigator: Silvio Osella

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Design, synthesis and characterization of luminescent molecular materials and coordination polymers derived from organoz...

Call: PRELUDIUM 7 , Panel: ST5

Principal investigator: Katarzyna Sołtys-Brzostek

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Fentanyl opioid designer drugs: from molecular modeling to in vitro studies

Call: OPUS 6 , Panel: ST4

Principal investigator: prof. Joanna Sadlej

Narodowy Instytut Leków

Design, parametrization and implementation of potentials of amino acid side chain interactions in water for application ...

Call: SONATA BIS 3 , Panel: ST4

Principal investigator: dr hab. Mariusz Makowski

Uniwersytet Gdański, Wydział Chemii

Computer aided design and prediction of properties of drug delivery systems based on carbon nanotubes architecture

Call: SONATA BIS 2 , Panel: ST4

Principal investigator: dr hab. Tomasz Pańczyk

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

The influence of molecular fingerprint bit density on chemical pattern recognition effectiveness

Call: PRELUDIUM 2 , Panel: NZ2

Principal investigator: Rafał Jerzy Kurczab

Instytut Farmakologii PAN

Design, synthesis and biological evaluation of Steroid Sulfatase Inhibitors based on organophosphorus compounds.

Call: SONATA 2 , Panel: NZ7

Principal investigator: dr Sebastian Demkowicz

Politechnika Gdańska