Design of photoswitchable dismantlers of biomaterials made of amyloid fibrils.

2018/31/B/ST4/03809

Keywords

Descriptors

  • ST4_15: Chemia teoretyczna i obliczeniowa
  • ST4_13: Chemia fizyczna układów biologicznych
  • ST5_12: Materiały "inteligentne" – materiały samoorganizujące się, materiały reagujące na bodźce zewnętrzne

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Instytut Biochemii i Biofizyki PAN

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Dorota Anna Niedziałek

Number of co-investigators in the project: 6

Call

OPUS 16 – announced on 2018-09-14

Amount awarded
618 600 PLN
Project start date
2019-06-18
Project end date
2024-03-17
Project duration
57 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. New Imaging Modality of COVID-19 Pneumonia Developed on the Basis of Alzheimer's Disease Research

    Authors:
    Koźmiński, Przemysław, Dorota Niedziałek, Grzegorz Wieczorek, Paweł K. Halik, Kamila Czarnecka, Aleksandra Rogut, Łukasz Cheda, Zbigniew Rogulski, Paweł Szymański, and Ewa Gniazdowska.
    Academic press:
    International Journal of Molecular Sciences (year: 2022, volume: 23(15), pages: 8405), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23158405 – link to the publication
  2. Novel Cyclopentaquinoline and Acridine Analogs as Multifunctional, Potent Drug Candidates in Alzheimer's Disease.

    Authors:
    Maciejewska, Karolina, Kamila Czarnecka, Paweł Kręcisz, Dorota Niedziałek, Grzegorz Wieczorek, Robert Skibiński, and Paweł Szymański.
    Academic press:
    International Journal of Molecular Sciences (year: 2022, volume: 23(11), pages: 5876), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23115876 – link to the publication
  3. A model of full-length RAGE in complex with S100B.

    Authors:
    Alexander Moysa, Kamil Steczkiewicz, Dorota Niedziałek, Dietmar Hammerschmid, Lilia Zhukova, Frank Sobott, Michal Dadlez
    Academic press:
    Structure (year: 2021, volume: 29(9), pages: 989-1002), Publisher: Cell Press
    Status:
    Published
    DOI:
    10.1016/j.str.2021.04.002 – link to the publication

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