Projects funded by the NCN
Stop the biting: tracking the insecticide-mediated allosteric changes in voltage-gated sodium channels and design of selective, photoactivated acyl sulfonamides. Towards understanding the molecular basis of the fast inactivation process.
2021/41/N/NZ3/02165
Keywords:
insecticides voltage-gated sodium channels inactivation gate fast inactivation docking molecular dynamics photoactivation
Descriptors:
- NZ3_005:
- ST3_016:
- NZ1_003:
Panel:
NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution :
Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Nauk Biologicznych i Weterynaryjnych
woj. kujawsko-pomorskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 20 - announced on 2021-03-15
Amount awarded: 131 455 PLN
Project start date (Y-m-d): 2022-02-04
Project end date (Y-m-d): 2025-02-03
Project duration:: 36 months (the same as in the proposal)
Project status: Project completed
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Toward Overcoming Pyrethroid Resistance in Mosquito Control: The Role of Sodium Channel Blocker InsecticidesAuthors:Beata Niklas, Jakub Rydzewski, Bruno Lapied, Wiesław NowakAcademic press:International Journal of Molecular Sciences (rok: 2023, tom: 24(12), strony: 10334-10351), Wydawca: MDPIStatus:PublishedDOI:10.3390/ijms241210334 - link to the publication