To what extent the transcriptomic response in the events initiating lung toxicity in mice depends on the structural features of the nanoparticles that cause it - TransNANO?
2020/37/B/ST5/01894
Keywords
Descriptors
- ST5_013: Metody badań materiałów /nanomateriałów
- ST5_001: Właściwości strukturalne materiałów
- NZ7_015: Toksykologia
Panel
ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering
Host institution
Uniwersytet Gdański, Wydział Chemii
Voivodeship: pomorskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 4
Call
OPUS 19 – announced on 2020-03-16
- Amount awarded
- 749 520 PLN
- Project start date
- 2021-10-01
- Project end date
- 2026-09-30
- Project duration
- 60 months (the same as in the proposal)
- Project status
- Pending project
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (6)
-
TRIumph in nanotoxicology: simplifying transcriptomics into a single predictive variable
- Authors:
- Viacheslav Muratov , Karolina Jagiełło, Tomasz Puzyn
- Academic press:
- Nanoscale Horizons (year: 2025, volume: 10, pages: 3116-3126), Publisher: Royal Society of Chemistry
- Status:
- Published
- DOI:
- 10.1039/D5NH00330J – link to the publication
-
A bibliometric analysis of the recent achievements in pulmonary safety of nanoparticles
- Authors:
- K. Falkiewicz, I. Fryca, K. Ciura, A. Mikolajczyk, K. Jagiello, T. Puzyn
- Academic press:
- Nanotoxicology (year: 2023, volume: 17, pages: 547-561), Publisher: Taylor & Francis
- Status:
- Published
- DOI:
- 10.1080/17435390.2023.2276411 – link to the publication
-
The impact of carbon nanotube properties on lung pathologies and atherosclerosis through acute inflammation: a new AOP-anchored in silico NAM
- Authors:
- Sattibabu Merugu , Karolina Jagiełło, Agnieszka Gajewicz-Skrętna, Sabina Halappanavar, Andrew Williams, Ulla Vogel, Tomasz Puzyn
- Academic press:
- Small (year: 2025, volume: 21, pages: 2501185 (1 of 10)), Publisher: Wiley-VCH GmbH, Weinheim
- Status:
- Published
- DOI:
- 10.1002/smll.202501185 – link to the publication
-
Toward nano-specific in silico NAMs: How to adjust nano-QSAR to the recent advancements of nanotoxicology?
- Authors:
- K. Ciura, E. Moschini, M. Stępnik. T. Serchi, A. Gutleb, K. Jarzyńska, K. Jagiello, T. Puzyn
- Academic press:
- Small (year: 2024, volume: 20, pages: 2305581), Publisher: Wiley
- Status:
- Published
- DOI:
- 10.1002/smll.202305581 – link to the publication
-
The role of machine learning in predicting titanium dioxide nanoparticles induced pulmonary pathology using transcriptomic biomarkers
- Authors:
- Viacheslav Muratov, Karolina Jagiełło, Alicja Mikołajczyk, Pernille Hogh Danielsen, Sabina Halappanavar, Ulla Vogel, Tomasz Puzyn
- Academic press:
- Journal of Hazardous Materials (year: 2025, volume: 493, pages: 138240), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.jhazmat.2025.138240 – link to the publication
-
An ancestral molecular response to nanomaterial particulates
- Authors:
- G. del Giudice, A. Serra, L. A. Saarimäki, K. Kotsis, I. Rouse, S. A. Colibaba, K. Jagiello, A. Mikolajczyk, M. Fratello, A. G. Papadiamantis, N. Sanabria, M. E. Annala, J. Morikka, P. A. S. Kinaret, E. Voyiatzis, G. Melagraki, A. Afantitis, K. Tämm, T. Puzyn, M. Gulumian, V. Lobaskin, I. Lynch, A. Federico & D. Greco
- Academic press:
- Nature Nanotechnology (year: 2023, volume: 18, pages: 957–966), Publisher: Springer Nature Limited
- Status:
- Published
- DOI:
- 10.1038/s41565-023-01393-4 – link to the publication