Projects funded by the NCN

The Dioscuri Centre for RNA-Protein Interactions in Human Health and Disease

Call: DIOSCURI 2 , Panel: NZ1

Principal investigator: dr Gracjan Michlewski

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej - Warszawa

Decoding signaling events inducing lipolysis in adipocytes during metabolic diseases

Call: DIOSCURI 1 , Panel: NZ4

Principal investigator: dr Grzegorz Sumara

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

Textural pyrolytic carbon (PyC) as a functional cousin of graphene nanomaterials in CF/PyC composites for neurobiomedica...

Call: PRELUDIUM 24 , Panel: ST11

Principal investigator: Ryszard Józef Wielowski

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie

Identification of age-related traces of Amyotrophic Lateral Sclerosis as a basis for the search for novel disease modifi...

Call: OPUS 29 , Panel: NZ5

Principal investigator: dr Agnieszka Marta Krzyżosiak

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

The stabilization mechanism and dissolution kinetics of co-amorphous systems - a new perspective on enhancing the effica...

Call: PRELUDIUM 24 , Panel: ST5

Principal investigator: Agata Olszewska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Iron deficiency and frailty syndrome in elderly patients with cardiovascular disease – cohort and interventional studies...

Call: OPUS 29 , Panel: NZ4

Principal investigator: prof. Ewa Anita Jankowska

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Are RIG-I-Like Receptors the Key to Understanding Galliformes' Susceptibility to Pathogens? Investigating the Role of MD...

Call: OPUS 29 , Panel: NZ9

Principal investigator: dr hab. Paweł Jan Sikorski

Uniwersytet Warszawski

Astrocytic Mitochondria in PACS2 Syndrome: Pathogenesis and Therapeutic Intervention

Call: PRELUDIUM 24 , Panel: NZ5

Principal investigator: Arkadiusz Franciszek Żbikowski

Uniwersytet Medyczny w Białymstoku

Dual-acting 5-HT6/5-HT7 receptor antagonists: exploring beneficial effects for the treatment of neurodegenerative disord...

Call: PRELUDIUM 24 , Panel: NZ7

Principal investigator: Michał Kamiński

Uniwersytet Jagielloński

Investigation of the therapeutic potential of natural flavour and fragrance materials in inflammatory oral diseases indu...

Call: PRELUDIUM 24 , Panel: NZ1

Principal investigator: Zuzanna Maria Bacińska

Politechnika Wrocławska

Impedimetric nanobiosensor for the detection of Chronic Kidney Disease based onternary Ti-Cu-Ag alloy.

Call: PRELUDIUM 24 , Panel: ST7

Principal investigator: Kamila Pasik

Uniwersytet Zielonogórski

The impact of H3 histamine receptor modulation on oligodendrogenesis and neurogenesis: a new strategy for the treatment ...

Call: PRELUDIUM 24 , Panel: NZ5

Principal investigator: Maciej Degutis

Instytut Farmakologii PAN

Neurotoxicity of nanoplastics - searching for the possible link between exposure to nanoplastics and neurodegenerative d...

Call: OPUS 29 , Panel: NZ7

Principal investigator: prof. Lidia Marta Strużyńska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

The Gut–Liver Axis in Ulcerative Colitis: How Inflammation, Microbiota, and Environmental Exposures Influence the Risk o...

Call: PRELUDIUM 24 , Panel: NZ4

Principal investigator: Alicja Aleksandra Kamińska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Multidimensional analysis of the gut microbiome, including the virome,archaeome, bacteriome, and mycobiome,along with ge...

Call: OPUS 29 , Panel: NZ4

Principal investigator: dr Agnieszka Aleksandra Krawczyk

Uniwersytet Jagielloński

Gene expression, protein concentration and enzymatic activity of redox enzymes in relation to trace element status in li...

Call: PRELUDIUM 24 , Panel: NZ1

Principal investigator: Jakub Piotr Adamus

Warszawski Uniwersytet Medyczny

Therapeutic evaluation of anti-fibrotic agents for thyroid eye disease (TED) in a preclinical mouse model

Call: PRELUDIUM 24 , Panel: NZ6

Principal investigator: Paweł Franciszek Tyrna

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

New aryl difluoromethylenephosphonic acid and thiazole conjugates as effective PTP1B inhibitors used in the treatment of...

Call: PRELUDIUM 24 , Panel: ST5

Principal investigator: Dominika Agnieszka Kołodziej-Sobczak

Uniwersytet Mikołaja Kopernika

Lipid-Proteasome Interplay in Aging and Proteostasis

Call: SONATINA 9 , Panel: NZ1

Principal investigator: Pankaj Thapa

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Preparation of pollen-like advanced drug delivery carriers for the treatment of chronic obstructive pulmonary disease

Call: SHENG 4 , Panel: ST5

Principal investigator: prof. Elżbieta Pamuła

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie

Positioning the aryl hydrocarbon receptor (AhR) as a new target for pharmacotherapy of sporadic Alzheimer disease: verif...

Call: OPUS 28 , Panel: NZ7

Principal investigator: prof. Małgorzata Kajta

Instytut Farmakologii PAN

The role of structural changes of lung surfactants in pulmonary diseases – from physicochemical description to effective...

Call: OPUS 28 , Panel: ST4

Principal investigator: dr hab. Dorota Matyszewska

Uniwersytet Warszawski

Study of the biomechanical relationship of the papillary muscle and the chordae tendineae in the mitral valve of the dog...

Call: OPUS 28 , Panel: NZ5

Principal investigator: prof. Agnieszka Noszczyk-Nowak

Uniwersytet Przyrodniczy we Wrocławiu

Advancing Skeletal Muscle Tissue Engineering: Biologically Active Bioinks for Drug-Induced Disease Modelling and On-Dema...

Call: OPUS 28 , Panel: ST8

Principal investigator: prof. Wojciech Święszkowski

Politechnika Warszawska

Defining The Role of Microbiome Mimicry in Type 1 Diabetes (T1D): a pilot study for Single-Cell Strain-characterisation ...

Call: OPUS 28 , Panel: NZ7

Principal investigator: dr Marcin Lukasz Pekalski

Wojskowy Instytut Medyczny

Clinical Variants of Hsp70 Chaperone HSPA1L in Protein Folding and Regulation of Glucocorticoid Receptor

Call: SONATA 20 , Panel: NZ5

Principal investigator: dr Agnieszka Antonina Kłosowska

Uniwersytet Gdański

A new concept of inhibiting the progression of Alzheimer's disease based on the modification of the blood-brain barrier ...

Call: OPUS 28 , Panel: NZ4

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii PAN

Genomic backgrounds of adaptive response of European ash (Fraxinus excelsior L.) populations to ash dieback disease caus...

Call: SONATA 20 , Panel: NZ9

Principal investigator: dr Joanna Meger

Uniwersytet Kazimierza Wielkiego

Fungal membrane modeling for selected antifungal compounds interactions

Call: SONATA 20 , Panel: NZ9

Principal investigator: dr Dominik Drabik

Politechnika Wrocławska

Gut-Brain Synergy: Development of an advanced microfluidic model of the microbiota-gut-brain axis to study mechanisms of...

Call: SONATA 20 , Panel: ST4

Principal investigator: dr Katarzyna Tokarska

Politechnika Warszawska

Bio-derived nanocarbon-based functional materials for next generation electroceutical devices

Call: M-ERA.NET 3 Call 2024 , Panel: ST5

Principal investigator: dr hab. Katarzyna Zofia Krukiewicz

Politechnika Śląska

The role of aged microglia in exacerbating Parkinson's Disease pathology

Call: OPUS 28 (LAP) , Panel: NZ5

Principal investigator: prof. Leonora Maria Bużańska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Molecular insights into NAD+ metabolism in Huntington's disease: role in pathophysiology and preclinical assessment of t...

Call: OPUS 28 , Panel: NZ5

Principal investigator: dr hab. Marta Urszula Tomczyk

Gdański Uniwersytet Medyczny

Galanin as the modulator of glucocorticoid secretion and its role in Cushing's Disease.

Call: SONATA 20 , Panel: NZ3

Principal investigator: dr Beata Joanna Mossakowska

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Metabolic disturbances involved in the pathogenesis of PACS2-related disorder

Call: OPUS 28 , Panel: NZ4

Principal investigator: prof. Mariusz Roman Więckowski

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Selective autophagy-mediated protein degradation as a potential therapeutic strategy for the treatment of inflammatory c...

Call: OPUS 28 , Panel: NZ7

Principal investigator: dr hab. Monika Emilia Marcinkowska

Uniwersytet Jagielloński

Factors affecting the exposure of large carnivores to health threats along an urbanization gradient

Call: OPUS 28 , Panel: NZ9

Principal investigator: dr hab. Sabina Pierużek-Nowak

Uniwersytet Warszawski

Carriage-Driven Evolutionary Mechanisms in Staphylococcus aureus

Call: SONATA 20 , Panel: NZ2

Principal investigator: dr Marta Matuszewska

Uniwersytet Warszawski

Gliadin deamidation by bacterial transglutaminases: significance in the pathogenesis of celiac disease.

Call: SONATA 20 , Panel: NZ7

Principal investigator: dr Eva Krzyżewska-Dudek

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Biotechnological method for production of 8-prenylnaringenin for application in treatment of inflammatory skin diseases

Call: SONATA 20 , Panel: ST8

Principal investigator: dr Jan Paweł Krzysztoforski

Politechnika Warszawska

Prevalence of viral genomes, histological, and immunohistochemical features of myocarditis in the myocardium, and freque...

Call: SONATA 20 , Panel: NZ6

Principal investigator: dr hab. Krzysztof Ozierański

Warszawski Uniwersytet Medyczny

The role of bile acid receptor TGR5 in insulin-dependent regulation of podocyte function and glomerular filtration barri...

Call: SONATA 20 , Panel: NZ4

Principal investigator: dr Patrycja Rachubik

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Volatilomics-based approaches for early detection and monitoring of infections in crops and soils

Call: SONATA 20 , Panel: NZ9

Principal investigator: dr Małgorzata Wesoły

Politechnika Warszawska

Lasing of nanoporous anodic alumina organic-fluorophore-infiltrated enabling an early-stage detection of neurodegenerati...

Call: SONATA 20 , Panel: ST11

Principal investigator: dr Grzegorz Jan Szwachta

Uniwersytet Warszawski

Analysis of the effects of proteotoxic stress on cholesterol homeostasis and its associations with cardiovascular diseas...

Call: OPUS 28 , Panel: NZ5

Principal investigator: prof. Wiesława Elżbieta Widłak

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

The first antibody-drug conjugates for Alzheimer's disease therapy

Call: SONATA BIS 14 , Panel: NZ5

Principal investigator: dr hab. Marcin Łukasz Poręba

Politechnika Wrocławska

IgLON5 disease: NeuroInflammatory Tauopathy and Encephalopathy: the Model for Inflammation towards early treatment of Ne...

Call: JPND Call 2024 , Panel: NZ4

Principal investigator: dr Natalia Eleonora Małek-Chudzik

Politechnika Wrocławska

Effect of Urolithin A on gut microbiota and intestinal integrity contributing to neuroprotective effects in a model of P...

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Olga Wojciechowska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Analysis of pharmacokinetic, pharmacodynamic and molecular determinants of intolerance and resistance to the Janus kinas...

Call: OPUS 27 , Panel: NZ7

Principal investigator: prof. Marta Katarzyna Karaźniewicz-Łada

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Autophagy stimulation by genistein to cure Alzheimer disease: mechanisms and effects investigated using genetic (cellula...

Call: OPUS 27 , Panel: NZ2

Principal investigator: prof. Grzegorz Władysław Węgrzyn

Uniwersytet Gdański