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Information on the principal investigator and host institution

Information of the project and the call

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Analysis of the plasma proteome in chronic kidney disease in the context of progressive cardiovascular disease.

2012/05/B/NZ2/02189

Keywords:

mass spectrometry chronic kidney disease cardiovascular disease protein/peptide profiles

Descriptors:

  • NZ2_3: Proteomics
  • NZ2_10: Biological systems analysis, modelling and simulation
  • NZ2_9: Systems biology

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Instytut Chemii Bioorganicznej PAN

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Magdalena Łuczak 

Number of co-investigators in the project: 5

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 405 000 PLN

Project start date (Y-m-d): 2013-03-01

Project end date (Y-m-d): 2016-09-30

Project duration:: 43 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zestaw komputerowy wraz z oprogramowaniem użytkowym (system operacyjny Windows, Office) oraz oprogramowaniem specjalistycznym (Statistica) (15 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (6)
  1. Optimization of Plasma Sample Pretreatment for Quantitative Analysis Using iTRAQ Labeling and LCMALDI- TOF/TOF
    Authors:
    Magdalena Luczak, Lukasz Marczak, Maciej Stobiecki
    Academic press:
    PLOS ONE (rok: 2014, tom: 9, strony: 7), Wydawca: PUBLIC LIBRARY SCIENCE
    Status:
    Published
    DOI:
    10.1371/journal.pone.0101694 - link to the publication
  2. Label-Free quantitative proteomics reveals differences in molecular mechanism of atherosclerosis related and non-related to chronic kidney disease
    Authors:
    M. Luczak, J. Suszynska-Zajczyk, L. Marczak, D. Formanowicz, E. Pawliczak, M. Wanic-Kossowska, M. Stobiecki
    Academic press:
    International Journal of Molecular Sciences (rok: 2016, tom: 17(5), strony: E631), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms17050631 - link to the publication
  3. iTRAQ-based proteomic analysis of plasma reveals abnormalities in lipid metabolism proteins in chronic kidney disease-related atherosclerosis
    Authors:
    M. Luczak, J. Suszynska-Zajczyk, L. Marczak, D. Formanowicz, E. Pawliczak, M. Wanic-Kossowska, M. Stobiecki
    Academic press:
    Scientific Reports (rok: 2016, tom: 6, strony: 32511), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/srep32511 - link to the publication
  4. Deeper insight into chronic kidney disease-related atherosclerosis: comparative proteomic studies of blood plasma using 2DE and mass spectrometry, Article Number: 20
    Authors:
    Luczak, M; Formanowicz, D; Marczak, L; Pawliczak, E; Wanic-Kossowska, M; Figlerowicz,; Stobiecki, M
    Academic press:
    Journal of Translational Medicine (rok: 2015, tom: Volume: 13, strony: 45309), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s12967-014-0378-8 - link to the publication
  1. Mass spectrometry-based relative quantitation of chronic kidney disease plasma proteins using iTRAQ and label-free strategies.
    Authors:
    M. Luczak, L. Marczak, M. Stobiecki
    Conference:
    The 33rd Informal Meeting on Mass Spectrometry, Szczyrk (rok: 2015, ), Wydawca: Institute of Organic Chemistry, Polish Academy of Sciences and Polish Mass Spectrometry Society
    Data:
    konferencja 10 - 13 maj
    Status:
    Published
  2. Alpha-microglobulin as a predictive marker for chronic kidney disease-related atherosclerosis.
    Authors:
    M. Luczak, D. Formanowicz, J. Suszynska-Zajczyk, Ł. Marczak, M. Stobiecki
    Conference:
    The 9th Central and Eastern Proteomic Conference. Poznań (rok: 2015, ), Wydawca: OŚRODEK WYDAWNICTW NAUKOWYCH (OWN)
    Data:
    konferencja 15-18 czerwiec
    Status:
    Published
  3. Optimization of plasma sample pretreatment for quantitative analysis using iTRAQ labeling and LC-MALDI-TOF/TOF
    Authors:
    M. Luczak, L. Marczak, M. Stobiecki.
    Conference:
    4th Conference of Polish Mass Spectrometry Society, Trzebnica, 2014 (rok: 2014, ), Wydawca: University of Wroclaw
    Data:
    konferencja 26-29.05.2014
    Status:
    Published
  4. Label free and iTRAQ-based proteomic analysis of plasma reveals differences in molecular mechanism of atherosclerosis related and non-related to chronic kidney disease
    Authors:
    M. Luczak, Ł. Marczak, J. Suszynska-Zajczyk, D Formanowicz, E. Pawliczak, M. Wanic-Kossowska, M. Stobiecki
    Conference:
    2nd Congress of Polish Biochemistry, Cell biology, Biotechnology and Bioinformatics (rok: 2016, ), Wydawca: Acta Biochimica Polonica wydawane przez Polskie Towarzystwo Biochemiczne i Komitet Biochemii i Biofizyki PAN
    Data:
    konferencja 13-16.09
    Status:
    Published
    DOI:
    link to the publication
  5. Analysis of the plasma proteome in the context of biomarkers research
    Authors:
    M. Luczak, L. Marczak, D. Formanowicz, E. Pawliczak, M. Wanic-Kossowska
    Conference:
    9th Annual Biomarkers Congress, Manchester, 2014 (rok: 2014, ), Wydawca: Oxford Global
    Data:
    konferencja 25-26.02.2014
    Status:
    Published
  6. Comprehensive analysis of chronic kidney disease plasma proteins using iTRAQ and label-free based relative quantitative proteomics.
    Authors:
    M. Luczak, Ł. Marczak, D. Formanowicz, M. Stobiecki.
    Conference:
    The 9th Central and Eastern Proteomic Conference. Poznań (rok: 2015, ), Wydawca: OŚRODEK WYDAWNICTW NAUKOWYCH (OWN)
    Data:
    konferencja 15-18 czerwiec
    Status:
    Published

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