Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Metabolic profiling of individuals with classic and genetic risk factors of coronary artery disease

2014/13/B/NZ5/03166

Keywords:

nmr spectroscopy genotyping metabolomics genomics coronary artery disease

Descriptors:

  • NZ5_3:
  • NZ5_1:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

ŚLĄSKIE CENTRUM CHORÓB SERCA

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Tadeusz Wacław Osadnik 

Number of co-investigators in the project: 4

Call: OPUS 7 - announced on 2014-03-17

Amount awarded: 1 997 655 PLN

Project start date (Y-m-d): 2015-02-25

Project end date (Y-m-d): 2019-01-24

Project duration:: 47 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (19)
  • Articles in post-conference publications (2)
  1. Metabolically healthy obese and metabolic syndrome of the lean: the importance of diet quality. Analysis of MAGNETIC cohort
    Authors:
    Osadnik K, Osadnik T, Lonnie M, Lejawa M, Reguła R, Fronczek M, Gawlita M, Wądołowska L, Gąsior M, Pawlas N
    Academic press:
    Nutrition Journal (rok: 2020, tom: 19, strony: 19), Wydawca: BMC Springer Nature
    Status:
    Published
    DOI:
    10.1186/s12937-020-00532-0 - link to the publication
  2. Metabolic and genetic profiling of young adults with and without family history of premature coronary heart disease (MAGNETIC). Study design and methodology.
    Authors:
    Tadeusz Osadnik, Kamila Osadnik, Natalia Pawlas, Joanna Strzelczyk, Janusz Kasperczyk, Lech Poloński, Mariusz Gąsior
    Academic press:
    Archives of Medical Science (rok: 2019, tom: online, strony: zaakceptowany), Wydawca: Termedia
    Status:
    Published
    DOI:
    10.5114/aoms.2018.75895 - link to the publication
  3. Association of Metabolically Healthy and Unhealthy Obesity Phenotype with Markers Related to Obesity, Diabetes among Young, Healthy Adult Men. Analysis of MAGNETIC Study
    Authors:
    Mateusz Lejawa, Kamila Osadnik, Zenon Czuba, Tadeusz Osadnik ,Natalia Pawlas
    Academic press:
    Life (Basel) (rok: 2021, tom: 11, strony: 1350), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/life11121350 - link to the publication
  4. Oxidative Stress in Association with Metabolic Health and Obesity in Young Adults
    Authors:
    Grzegorz K Jakubiak, Kamila Osadnik, Mateusz Lejawa, Sławomir Kasperczyk, Tadeusz Osadnik, Natalia Pawlas
    Academic press:
    Oxidative Medicine and Cellular Longevity (rok: 2021, tom: 2021, strony: Volume 2021, Article ID 9987352, 19 pages), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2021/9987352 - link to the publication
  5. "Obesity and Insulin Resistance" Is the Component of the Metabolic Syndrome Most Strongly Associated with Oxidative Stress
    Authors:
    Grzegorz K Jakubiak , Kamila Osadnik, Mateusz Lejawa , Tadeusz Osadnik , Marcin Goławski , Piotr Lewandowski , Natalia Pawlas
    Academic press:
    Antioxidants (Basel) (rok: 2021, tom: 11, strony: 79), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/antiox11010079 - link to the publication
  6. New Variants of the Cytochrome P450 2R1 (CYP2R1) Gene in Individuals with Severe Vitamin D-Activating Enzyme 25(OH)D Deficiency
    Authors:
    Martyna Fronczek , Joanna Katarzyna Strzelczyk, Krzysztof Biernacki , Silvia Salatino, Tadeusz Osadnik, Zofia Ostrowska
    Academic press:
    Biomolecules (rok: 2021, tom: 11, strony: 1867), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/biom11121867 - link to the publication
  7. "Obesity and Insulin Resistance" Is the Component of the Metabolic Syndrome Most Strongly Associated with Oxidative Stress
    Authors:
    Grzegorz K Jakubiak , Kamila Osadnik, Mateusz Lejawa , Tadeusz Osadnik , Marcin Goławski , Piotr Lewandowski , Natalia Pawlas
    Academic press:
    Antioxidants (Basel) (rok: 2021, tom: 11, strony: 79), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/antiox11010079 - link to the publication
  8. Calcium and Phosphate Levels are Among Other Factors Associated with Metabolic Syndrome in Patients with Normal Weight
    Authors:
    Kamila Osadnik, Tadeusz Osadnik, Marcin Delijewski, Mateusz Lejawa, Martyna Fronczek, Rafał Reguła, Mariusz Gąsior, Natalia Pawlas
    Academic press:
    Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy (rok: 2020, tom: 13, strony: 1281-1288), Wydawca: DOVE Press
    Status:
    Published
    DOI:
    10.2147/DMSO.S232497 - link to the publication
  9. High progesterone levels are associated with family history of premature coronary artery disease in young healthy adult men
    Authors:
    Tadeusz Osadnik, Natalia Pawlas, Kamila Osadnik, Kamil Bujak, Marta Góral, Mateusz Lejawa, Martyna Fronczek, Rafał Reguła, Hanna Czarnecka, Marcin Gawlita, Joanna Katarzyna Strzelczyk, Małgorzata Gonera, Marek Gierlotka, Lech Poloński, Mariusz Gąsior
    Academic press:
    PLoS One (rok: 2019, tom: 14, strony: e0215302), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0215302 - link to the publication
  10. Oxidative Stress in Association with Metabolic Health and Obesity in Young Adults
    Authors:
    Grzegorz K Jakubiak, Kamila Osadnik, Mateusz Lejawa, Sławomir Kasperczyk, Tadeusz Osadnik, Natalia Pawlas
    Academic press:
    Oxidative Medicine and Cellular Longevity (rok: 2021, tom: 2021, strony: Volume 2021, Article ID 9987352, 19 pages), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2021/9987352 - link to the publication
  11. Calcium and Phosphate Levels are Among Other Factors Associated with Metabolic Syndrome in Patients with Normal Weight
    Authors:
    Kamila Osadnik, Tadeusz Osadnik, Marcin Delijewski, Mateusz Lejawa, Martyna Fronczek, Rafał Reguła, Mariusz Gąsior, Natalia Pawlas
    Academic press:
    Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy (rok: 2020, tom: 13, strony: 1281-1288), Wydawca: DOVE Press
    Status:
    Published
    DOI:
    10.2147/DMSO.S232497 - link to the publication
  12. High progesterone levels are associated with family history of premature coronary artery disease in young healthy adult men
    Authors:
    Tadeusz Osadnik, Natalia Pawlas, Kamila Osadnik, Kamil Bujak, Marta Góral, Mateusz Lejawa, Martyna Fronczek, Rafał Reguła, Hanna Czarnecka, Marcin Gawlita, Joanna Katarzyna Strzelczyk, Małgorzata Gonera, Marek Gierlotka, Lech Poloński, Mariusz Gąsior
    Academic press:
    PLoS One (rok: 2019, tom: 14, strony: e0215302), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0215302 - link to the publication
  13. Novel inflammatory biomarkers may reflect subclinical inflammation in young healthy adults with obesity
    Authors:
    Osadnik T1, Bujak K, Osadnik K, Czarnecka H, Pawlas N, Reguła R, Fronczek M, Lejawa M, Gawlita M, Gonera M, Góral M, Strzelczyk JK, Gierlotka M, Lekston A, Kasperczyk J, Poloński L, Gąsior M.
    Academic press:
    Endokrynologia Polska (rok: 2019, tom: PMID: 30633318, strony: 45676), Wydawca: Via Medica
    Status:
    Published
    DOI:
    10.5603/EP.a2019.0002 - link to the publication
  14. Family History of Premature Coronary Artery Disease (P-CAD)—A Non-Modifiable Risk Factor? Dietary Patterns of Young Healthy Offspring of P-CAD Patients: A Case-Control Study (MAGNETIC Project)
    Authors:
    Tadeusz Osadnik, Natalia Pawlas, Marta Lonnie, Kamila Osadnik, Mateusz Lejawa, Lidia Wądołowska 4, Kamil Bujak 6, Martyna Fronczek, Rafał Reguła, Marcin Gawlita, Joanna Katarzyna Strzelczyk, Marta Góral, Marek Gierlotka, Lech Poloński, Mariusz Gąsior
    Academic press:
    Nutrients (rok: 2018, tom: 1488, strony: 45670), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nu10101488 - link to the publication
  15. Association of Metabolically Healthy and Unhealthy Obesity Phenotypes with Oxidative Stress Parameters and Telomere Length in Healthy Young Adult Men. Analysis of the MAGNETIC Study
    Authors:
    Mateusz Lejawa, , Kamila Osadnik, Tadeusz Osadnik, Natalia Pawlas
    Academic press:
    Antioxidants (rok: 2021, tom: 10, strony: 93), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/antiox10010093 - link to the publication
  16. Association of Metabolically Healthy and Unhealthy Obesity Phenotype with Markers Related to Obesity, Diabetes among Young, Healthy Adult Men. Analysis of MAGNETIC Study
    Authors:
    Mateusz Lejawa, Kamila Osadnik, Zenon Czuba, Tadeusz Osadnik ,Natalia Pawlas
    Academic press:
    Life (Basel) (rok: 2021, tom: 11, strony: 1350), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/life11121350 - link to the publication
  17. Genetic and environmental factors associated with homocysteine concentrations in a population of healthy young adults. Analysis of the MAGNETIC study
    Authors:
    Tadeusz Osadnik, Natalia Pawlas, Mateusz Lejawa, Małgorzata Lisik, Kamila Osadnik, Martyna Fronczek, Kamil Bujak, Mariusz Gąsior
    Academic press:
    Nutrition, Metabolism and Cardiovascular Diseases (rok: 2020, tom: 30, strony: 939-947), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.numecd.2020.01.012 - link to the publication
  18. New Variants of the Cytochrome P450 2R1 (CYP2R1) Gene in Individuals with Severe Vitamin D-Activating Enzyme 25(OH)D Deficiency
    Authors:
    Martyna Fronczek , Joanna Katarzyna Strzelczyk, Krzysztof Biernacki , Silvia Salatino, Tadeusz Osadnik, Zofia Ostrowska
    Academic press:
    Biomolecules (rok: 2021, tom: 11, strony: 1867), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/biom11121867 - link to the publication
  19. Genetic and environmental factors associated with homocysteine concentrations in a population of healthy young adults. Analysis of the MAGNETIC study
    Authors:
    Tadeusz Osadnik, Natalia Pawlas, Mateusz Lejawa, Małgorzata Lisik, Kamila Osadnik, Martyna Fronczek, Kamil Bujak, Mariusz Gąsior
    Academic press:
    Nutrition, Metabolism and Cardiovascular Diseases (rok: 2020, tom: 30, strony: 939-947), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.numecd.2020.01.012 - link to the publication
  1. METABOLOMIC FINDINGS IN YOUNG OBESE MEN AND CONTROLS
    Authors:
    K. Osadnik, T. Osadnik, N. Pawlas, M. Gawlita, R. Reguła, K. Bujak, M. Fronczek, M. Lejawa, J. Jaworska, J. Strzelczyk, M. Gąsior , J. Kasperczyk
    Conference:
    10th International Symposium on Biological Monitoring in Occupational and Environmental Health (ISBM-10) (rok: 2017, ), Wydawca: Organizator Konferencji
    Data:
    konferencja 1-4 October
    Status:
    Published
  2. METABOLOMIC FINDINGS IN YOUNG OBESE MEN AND CONTROLS
    Authors:
    K. Osadnik, T. Osadnik, N. Pawlas, M. Gawlita, R. Reguła, K. Bujak, M. Fronczek, M. Lejawa, J. Jaworska, J. Strzelczyk, M. Gąsior , J. Kasperczyk
    Conference:
    10th International Symposium on Biological Monitoring in Occupational and Environmental Health (ISBM-10) (rok: 2017, ), Wydawca: Organizator Konferencji
    Data:
    konferencja 1-4 October
    Status:
    Published

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