Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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PrP amyloid as a model amyloid formation in transgenic mice, in chronic wasting disease - a novel prion disease

2012/04/M/NZ4/00232

Keywords:

CWD - prion diseases - prion - amyloid

Descriptors:

  • NZ6_5: Virology
  • NZ3_6: Cell neurobiology
  • NZ7_11: Veterinary healthcare

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski z Oddziałem Stomatologicznym

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Paweł Liberski 

Number of co-investigators in the project: 6

Call: HARMONIA 2 - announced on 2011-12-15

Amount awarded: 465 300 PLN

Project start date (Y-m-d): 2012-09-18

Project end date (Y-m-d): 2015-09-17

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  1. Electron microscopic and confocal laser microscopy analysis of amyloid plaques in chronic wasting disease transmitted to transgenic mice
    Authors:
    Beata Sikorska, Agata Gajos, Andrzej Bogucki, Emil Zielonka Christina Sigurdson and Pawel P. Liberski
    Academic press:
    Prion (rok: 2017, tom: -, strony: -), Wydawca: Taylor&Francis
    Status:
    Submitted
  2. De novo prion aggregates trigger autophagy in skeletal muscle
    Authors:
    Joshi-Barr S, Bett C, Chiang WC, Trejo M, Goebel HH, Sikorska B, Liberski PP, Raeber A, Lin JH, Masliah E Sigurdson CJ
    Academic press:
    Journal of Virology (rok: 2014, tom: 88, strony: 2071-82), Wydawca: American Society for Microbiology
    Status:
    Published
    DOI:
    10.1128/JVI.02279-13 - link to the publication