Projects funded by the NCN

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199 projects found matching your search criteria :

  1. Modulation of amygdala neural network activity by the 5-HT7 receptor

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: prof. Krzysztof Tokarski

    Instytut Farmakologii PAN

  2. The role of synovial fibroblasts' activity in joint pain in osteoarthritis

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Maria Starowicz-Bubak

    Instytut Farmakologii PAN

  3. Role of oxidative stress and ceramide in the pathogenesis of depression and in the mechanizm of action of antidepressant...

    Call: PRELUDIUM 12 , Panel: NZ5

    Principal investigator: Justyna Józefa Brodowicz

    Instytut Farmakologii PAN

  4. Pharmacological and optogenetic investigation of the mechanism of action of Deep Brain Stimulation of the ventromedial p...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii PAN

  5. The role of endoplasmic reticulum stress in the pathomechanisms of early-life stress-induced dysfunction of the prefrona...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Chocyk

    Instytut Farmakologii PAN

  6. Functional dissection of three alpha(1)-adrenergic receptor subtypes in the effects of antidepressant drugs: exploitatio...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Irena Maria Nalepa

    Instytut Farmakologii PAN

  7. The role of the neuron-microglia CX3CL1-CX3CR1 and CD200-CD200R protein systems in molecular mechanisms of antipsychotic...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  8. Fingerprint Połączeń Podstrukturalnych - nowa metoda reprezentacji związków chemicznych

    Call: ETIUDA 4 , Panel: NZ2

    Principal investigator: Krzysztof Rataj

    Instytut Farmakologii PAN

  9. Maternal diet during gestation and nutrition as a risk factor for cocaine use disorder in offspring - preclinical behavi...

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: prof. Małgorzata Maria Filip

    Instytut Farmakologii PAN

  10. Molecular mechanism of unique action of clozapine in the context of GPCR.

    Call: OPUS 8 , Panel: NZ7

    Principal investigator: dr Agata Faron-Górecka

    Instytut Farmakologii PAN

  11. Wykorzystanie metod uczenia maszynowego w zadaniach komputerowo wspomaganego projektowania leków.

    Call: ETIUDA 3 , Panel: NZ2

    Principal investigator: Sabina Marta Podlewska

    Instytut Farmakologii PAN

  12. Rational design and evaluation of functionally biased opioid agonists

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Ryszard Przewłocki

    Instytut Farmakologii PAN

  13. Ocena roli wybranych białek neuronalnych i mikroglejowych w patogenezie schizofrenii - badania w modelu zwierzęcym.

    Call: ETIUDA 7 , Panel: NZ4

    Principal investigator: Katarzyna Anna Chamera

    Instytut Farmakologii PAN

  14. Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii PAN

  15. Influence of modified maternal diet on the phenotype of offspring: behavioral and molecular correlations

    Call: ETIUDA 8 , Panel: NZ7

    Principal investigator: Kinga Eryka Gawlińska

    Instytut Farmakologii PAN

  16. Combined administration of muscarinic receptor antagonists and group II/III metabotropic glutamate (mGlu) receptor ligan...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Andrzej Mikołaj Pilc

    Instytut Farmakologii PAN

  17. Molecular profiling of novel antipsychotic drug candidates

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr hab. Jan Manuel Rodriguez Parkitna

    Instytut Farmakologii PAN

  18. Selective activation of non-nuclear Estrogen Receptor signaling with PaPE-1 as a novel therapeutic approach for sporadic...

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii PAN

  19. The developmental changes in the endogenous opioid system associated with altered sensitivity to reward during adolescen...

    Call: PRELUDIUM 21 , Panel: NZ4

    Principal investigator: Klaudia Weronika Misiołek

    Instytut Farmakologii PAN

  20. Early-life programming for neurodevelopmental disorders: search for a prodrome target within the vascular network in a r...

    Call: OPUS 23 , Panel: NZ4

    Principal investigator: prof. Małgorzata Maria Filip

    Instytut Farmakologii PAN

  21. Modeling Progression of α-Synucleinopathy in Noradrenergic and Serotonergic Systems – Possible Link with Prodromal Sympt...

    Call: PRELUDIUM 23 , Panel: NZ4

    Principal investigator: Anna Hajam Alwani

    Instytut Farmakologii PAN

  22. Positioning the aryl hydrocarbon receptor (AhR) as a new target for pharmacotherapy of sporadic Alzheimer disease: verif...

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii PAN

  23. Impact of endocrine disrupting chemicals - 4,para nonylphenol - on toxic effects mediated by xenobiotic receptors PXR an...

    Call: PRELUDIUM 1 , Panel: NZ4

    Principal investigator: Ewa Joanna Litwa

    Instytut Farmakologii PAN

  24. Define the role and modulation of immune diabetes changed factors - their importance to the action of analgesics.

    Call: PRELUDIUM 3 , Panel: NZ4

    Principal investigator: Magdalena Małgorzata Żychowska

    Instytut Farmakologii PAN

  25. Probing the selectivity of zinc allosteric modulation in various serotonin receptor subtypes

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: Grzegorz Marek Satała

    Instytut Farmakologii PAN

  26. Molecular markers of stress resilience in animal model of depression

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: prof. Marta Dziedzicka-Wasylewska

    Instytut Farmakologii PAN

  27. The influence of glucagon-like peptied-1 receptor agaonists on regulation of coticotropin-releasing hormone gene promote...

    Call: PRELUDIUM 4 , Panel: NZ7

    Principal investigator: Jan Stanisław Detka

    Instytut Farmakologii PAN

  28. Involvement of 5-HT1A receptor signal pathway in the antidepressant effect of zinc

    Call: HARMONIA 4 , Panel: NZ7

    Principal investigator: dr Bernadeta Szewczyk

    Instytut Farmakologii PAN

  29. Molecular mechanism for the effects of stress hormones on development of drug addiction

    Call: MAESTRO 4 , Panel: NZ3

    Principal investigator: prof. Ryszard Przewłocki

    Instytut Farmakologii PAN

  30. The role of brain glutamatergic system in the neuroendocrine regulation of cytochrome P450 expression and activity in th...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: prof. Władysława Anna Daniel

    Instytut Farmakologii PAN

  31. Regulation of alternative Dclk1 kinase gene isoforms by psychotropic drugs

    Call: PRELUDIUM 12 , Panel: NZ3

    Principal investigator: Magdalena Agata Zygmunt

    Instytut Farmakologii PAN

  32. The effects of thyroid hormones in the brain in an animal model of depression

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Bogusława Budziszewska

    Instytut Farmakologii PAN

  33. How microglia-astrocyte interaction affects neuronal functioning in the dopaminergic system. Analysis of the protective ...

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr Katarzyna Zofia Kuter

    Instytut Farmakologii PAN

  34. Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

    Call: OPUS 15 , Panel: NZ7

    Principal investigator: prof. Barbara Elżbieta Przewłocka

    Instytut Farmakologii PAN

  35. Wpływ wybranych chemokin na właściwości komórek nerwowych i przekaźnictwo synaptyczne w obszarze kompleksu ciała migdało...

    Call: ETIUDA 7 , Panel: NZ4

    Principal investigator: Joanna Ewa Sowa

    Instytut Farmakologii PAN

  36. Endocannabinoid regulation of the motivational tone at the mesolimbic system driven by inflammation

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Katarzyna Maria Starowicz-Bubak

    Instytut Farmakologii PAN

  37. Kappa opioid receptors integrate neuronal signaling involved in social behavior

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Jan Manuel Rodriguez Parkitna

    Instytut Farmakologii PAN

  38. Role of the NLRP3 inflammasome in the mechanisms of action of antidepressant drugs - study in an animal model of depress...

    Call: PRELUDIUM 9 , Panel: NZ7

    Principal investigator: dr Ewa Izabela Trojan

    Instytut Farmakologii PAN

  39. Changes in neurogenesis during withdrawal from nicotine self-administration in rats - role of serotonin (5-HT)2C recepto...

    Call: OPUS 9 , Panel: NZ4

    Principal investigator: dr Magdalena Joanna Zaniewska

    Instytut Farmakologii PAN

  40. The role of microRNA biogenesis system in vulnerability and resilience to stress in an animal model of depression

    Call: PRELUDIUM 9 , Panel: NZ4

    Principal investigator: Dariusz Marek Żurawek

    Instytut Farmakologii PAN

  41. Substructural Connectivity Fingerprint and Extreme Entropy Machines: A New Method of Compound Representation and Analysi...

    Call: PRELUDIUM 9 , Panel: ST6

    Principal investigator: Krzysztof Rataj

    Instytut Farmakologii PAN

  42. A virtual screening protocol based on automatically generated structure-based pharmacophore models.

    Call: HARMONIA 7 , Panel: NZ2

    Principal investigator: Stefan Mateusz Mordalski

    Instytut Farmakologii PAN

  43. Adaptacyjne podejmowanie decyzji u zwierząt z komórkowo specyficzną inaktywacją receptorów glutaminianu w układzie dopam...

    Call: ETIUDA 4 , Panel: NZ4

    Principal investigator: Przemysław Eligiusz Cieślak

    Instytut Farmakologii PAN

  44. Determination of the mechanisms and potential targets for neuropathic pain therapy by investigating pharmacological inte...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Anna Piotrowska-Murzyn

    Instytut Farmakologii PAN

  45. The role of codependent 5-HT1a and 5-HT7 receptor signalling in the hippocampal stress response

    Call: PRELUDIUM 12 , Panel: NZ4

    Principal investigator: Marcin Siwiec

    Instytut Farmakologii PAN

  46. Development of a tool for automatic evaluation of complexes of ligands with serotonin receptors based on the application...

    Call: PRELUDIUM 5 , Panel: NZ2

    Principal investigator: Sabina Marta Podlewska

    Instytut Farmakologii PAN

  47. Neuronal and nonneuronal mechanisms of Bont/A effects in neuropathic pain development - behavioral and biochemical studi...

    Call: HARMONIA 5 , Panel: NZ4

    Principal investigator: dr hab. Joanna Gabriela Mika

    Instytut Farmakologii PAN

  48. The significance of the serotonergic innervation of the brain hypothalamus in the regulation of cytochrome P450

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: prof. Władysława Anna Daniel

    Instytut Farmakologii PAN

  49. The role of the factors involved in the brain glucose metabolism in the model of obesity and depression comorbidity

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: prof. Bogusława Budziszewska

    Instytut Farmakologii PAN

  50. Neurotoxic effects of benzophenone-3 : the role of estrogen receptors and retinoid X receptor alpha.

    Call: PRELUDIUM 7 , Panel: NZ4

    Principal investigator: Agnieszka Wnuk

    Instytut Farmakologii PAN

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