Projects funded by the NCN


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29 projects found matching your search criteria :

  1. RNA hybrid duplex-quadruplex structures with dual functionality as a new tool for silecing of gene expression

    Call: OPUS 7 , Panel: ST5

    Principal investigator: prof. Zofia Janina Gdaniec

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  2. P-Stereodefined phosphorothioate analogs of DNA containing within nucleobases modifications preventing Watson-Crick base...

    Call: OPUS 6 , Panel: ST5

    Principal investigator: dr Anna Maciaszek

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  3. New methods for mRNA 5' end labeling and examples of their application in studies on RNA metabolism and searching for in...

    Call: OPUS 5 , Panel: ST5

    Principal investigator: dr hab. Jacek Jemielity

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  4. Structure defined oligonucleotides for revealing fundamental insights into structure and function of RNAs

    Call: MAESTRO 4 , Panel: ST5

    Principal investigator: prof. Ryszard Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  5. Development of chemical method for synthesis of biologically active triphosphates using thermolabile protecting groups

    Call: OPUS 4 , Panel: ST5

    Principal investigator: dr hab. Marcin Krzysztof Chmielewski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  6. Multitasking polymeric lattices included selected DNA oligonucleotide sequences - synthesis, modifications and physioche...

    Call: SONATA 3 , Panel: ST5

    Principal investigator: dr Ewelina Zabost

    Uniwersytet Warszawski, Wydział Chemii

  7. Stereodefined phosphorothioate analogs of DNA with incorporated LNA-type nucleosides - synthesis and properties of compl...

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr hab. Piotr Jerzy Guga

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  8. New approaches towards modulating selective and functional activities of antisense oligonucleotides

    Call: OPUS 2 , Panel: ST5

    Principal investigator: prof. Ryszard Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  9. Evaluation of the therapeutic potential of synthetic miRNA-223-3p analog in a rat model of severe asthma

    Call: SONATA 19 , Panel: NZ4

    Principal investigator: dr Wojciech Jerzy Langwiński

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  10. Design and synthesis of new rifampicin analogs as a source of effective bacterial RNA polymerase inhibitors

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr hab. Piotr Przybylski

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  11. Injectable and RNA-releasing nanofibrous microcarriers for intervertebral disc regeneration

    Call: SONATA BIS 13 , Panel: ST5

    Principal investigator: dr Paweł Nakielski

    Instytut Podstawowych Problemów Techniki Polskiej Akademii Nauk

  12. Elongation factors in synthesis of developmentally controlled non-coding RNA

    Call: OPUS 23 , Panel: NZ2

    Principal investigator: dr Jacek Krzysztof Nowak

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  13. Crystallographic analysis of RNA-ligand complexes. Towards rational design oflead compounds for development of therapies...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Ludmiła Kiliszek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  14. Synthesis and structural/biophysical studies of model mRNA/mt-tRNA oligomers to evaluate the role of modified nucleoside...

    Call: OPUS 22 , Panel: ST4

    Principal investigator: dr hab. Grażyna Bożena Leszczyńska

    Politechnika Łódzka

  15. Multifunctional smart nanostructured platforms for light-triggered wound healing polytherapy

    Call: SONATA BIS 10 , Panel: ST5

    Principal investigator: dr hab. Filippo Pierini

    Instytut Podstawowych Problemów Techniki Polskiej Akademii Nauk

  16. Cellular adaptation to cold.

    Call: GRIEG 1 , Panel: NZ3

    Principal investigator: dr Wojciech Mieczysław Pokrzywa

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

  17. Synthesis and characterization of new molecular probes for monitoring activity of enzymes associated with RNA decapping ...

    Call: OPUS 16 , Panel: ST5

    Principal investigator: dr hab. Joanna Kowalska

    Uniwersytet Warszawski, Wydział Fizyki

  18. Role of RNA binding proteins in resistance to therapy of leukemia cells in bone marrow niche

    Call: HARMONIA 10 , Panel: NZ3

    Principal investigator: dr Paulina Podszywałow-Bartnicka

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  19. Why Nature introduced selenium to wobble nucleosides in transfer RNA?

    Call: OPUS 15 , Panel: ST5

    Principal investigator: prof. Barbara Czesława Nawrot

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  20. Synthesis and structural studies of oligonucleotides with tRNA anticodon stem-loop sequences containing newly discovered...

    Call: OPUS 13 , Panel: ST5

    Principal investigator: prof. Elżbieta Jadwiga Sochacka

    Politechnika Łódzka, Wydział Chemiczny

  21. How RNA structure governs messenger RNA function? Exploring structural and functional aspects essential for synthesis of...

    Call: SONATA 12 , Panel: NZ1

    Principal investigator: dr Leszek Michał Błaszczyk

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  22. Identification of nucleolar protein partners of phosphoglycerate mutase muscle isoenzyme - PGAM2

    Call: PRELUDIUM 11 , Panel: NZ1

    Principal investigator: Janusz Wiśniewski

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  23. Chemically modified mRNA for studies on cellular processes and therapeutic applications

    Call: OPUS 11 , Panel: ST5

    Principal investigator: prof. Jacek Jemielity

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  24. Double stranded probes, in which both oligonucleotide components hybridize according to the Hoogsteen's interactions, an...

    Call: OPUS 10 , Panel: ST5

    Principal investigator: dr hab. Piotr Jerzy Guga

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  25. Tecto-RNA nano-structures for gene expression regulation in a model system

    Call: OPUS 10 , Panel: ST5

    Principal investigator: dr hab. Arkadiusz Chworoś

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  26. catalytic nucleic acids in of the new generation in the regulation of genetic information

    Call: OPUS 9 , Panel: ST5

    Principal investigator: prof. Jan Barciszewski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  27. Study of the mechanisms involved in synthesis of non-coding transcripts

    Call: OPUS 9 , Panel: NZ2

    Principal investigator: dr Jacek Krzysztof Nowak

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  28. Dissecting mechanisms of RNA-based Stress Granules formation, their structure and role in the development of Multi-Drug ...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: dr hab. Witold Szaflarski

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

  29. Studies on influence of cytochrome c on oxidative damage of 2-thiouridines built in an RNA chain

    Call: PRELUDIUM 9 , Panel: ST5

    Principal investigator: Anna Maria Chwiałkowska

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk