Projects funded by the NCN
How RNA structure governs messenger RNA function? Exploring structural and functional aspects essential for synthesis of p53 protein - a master regulator of vital cellular functions
2016/23/D/NZ1/02565
Keywords:
RNA structure RNA folding long-range RNA-RNA interactions RNA-protein interactions p53 mRNA protein translation
Descriptors:
- NZ1_4: Structural biology
- NZ1_1: Molecular biology
Panel:
NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution :
Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
woj. wielkopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 4
Call: SONATA 12 - announced on 2016-09-15
Amount awarded: 533 280 PLN
Project start date (Y-m-d): 2017-08-17
Project end date (Y-m-d): 2023-02-16
Project duration:: 66 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Urządzenie mieszające z funkcją kontroli temperatury (13 500 PLN)
- Aparat do transferu kompleksów białko-RNA na membranę (9 000 PLN)
- Komputer wraz z oprogramowaniem (10 000 PLN)
- Termocykler PCR z trzema niezależnymi blokami grzejnymi (45 000 PLN)
Information in the final report
- Publication in academic press/journals (1)
- Exploring structural determinants and the role of nucleolin in formation of the long-range interactions between untranslated regions of p53 mRNAAuthors:Agnieszka Kiliszek, Wojciech Rypniewski, Leszek BłaszczykAcademic press:RNA Journal (rok: 2023, tom: 29, strony: bd), Wydawca: COLD SPRING HARBOR LAB PRESSStatus:PublishedDOI:10.1261/rna.079378.122 - link to the publication