Projects funded by the NCN

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81 projects found matching your search criteria :

  1. Phosphorylation-Dependent Regulation of IRS2 by DYRK1A: Implications for Diabetes Therapy

    Call: PRELUDIUM 24 , Panel: NZ1

    Principal investigator: Alicja Bis

    Uniwersytet Jagielloński

  2. The role of the ABCA1 protein in cholesterol metabolism and the organization of key cell membrane structures in the proc...

    Call: PRELUDIUM 24 , Panel: NZ7

    Principal investigator: Aleksandra Mordzińska-Rak

    Uniwersytet Medyczny w Lublinie

  3. Identification of proteolytic cleavage sites in peptide substrates using coarse-grained docking and machine learning met...

    Call: OPUS 29 , Panel: NZ1

    Principal investigator: dr hab. Michał Koliński

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  4. Targeted Degradation of the MLL Complex in Leukemia: A PROTAC-Based Therapeutic Strategy

    Call: SONATINA 9 , Panel: ST5

    Principal investigator: dr Natalia Anna Skrzypczak

    Fundacja Uniwersytetu im. Adama Mickiewicza

  5. Design of coiled-coil and alpha/beta non-trivial protein folds that self-assemble in silico and in vitro.

    Call: OPUS 28 , Panel: NZ1

    Principal investigator: dr hab. Joanna Ida Sułkowska

    Uniwersytet Warszawski

  6. Factors associated with a modulation of fibrin clot structure and resistance to fibrinolysis in patients with protein C ...

    Call: OPUS 28 , Panel: NZ5

    Principal investigator: dr hab. Michał Tomasz Ząbczyk

    Krakowski Szpital Specjalistyczny im. Jana Pawła II

  7. Unlocking the unused capacity of bacterial metabolism through the rational design of substrate transporters

    Call: OPUS 28 (LAP) , Panel: NZ1

    Principal investigator: dr hab. Jan Brezovsky

    Uniwersytet im. Adama Mickiewicza w Poznaniu

  8. Changes in protein citrullination profile and chromatin structure induced by peptidyl-arginine deiminases activity and t...

    Call: PRELUDIUM 23 , Panel: NZ3

    Principal investigator: dr Oskar Kazimierz Ciesielski

    Uniwersytet Łódzki

  9. Deciphering the Molecular Mechanism of Queuosinylation of Human tRNA: Structural and Functional Analyses of the QTRT1/2 ...

    Call: PRELUDIUM 23 , Panel: NZ1

    Principal investigator: Igor Kaczmarczyk

    Uniwersytet Jagielloński

  10. The SERRATE protein determines the secondary structure of microRNA precursors

    Call: OPUS 27 , Panel: NZ1

    Principal investigator: dr Mateusz Michał Bajczyk

    Uniwersytet im. Adama Mickiewicza w Poznaniu

  11. Principles of hidden zinc bioinorganic chemistry: Tuning sequence-structure-stability relationships for enhanced zinc pr...

    Call: OPUS 27 , Panel: ST4

    Principal investigator: prof. Artur Krężel

    Uniwersytet Wrocławski

  12. Investigating the potential of protein-pectin complexes to improve the functional properties of 3D printing inks

    Call: PRELUDIUM 23 , Panel: NZ9

    Principal investigator: Magdalena Urszula Trusińska

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie

  13. Deciphering the unknown - structure and function of Nif3 protein

    Call: SONATINA 8 , Panel: NZ1

    Principal investigator: Elżbieta Wątor-Wilk

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  14. Correlated mean-field interactions propagated along polypeptide chain as a key to understanding the structure formation,...

    Call: OPUS 26 , Panel: ST4

    Principal investigator: prof. Józef Adam Liwo

    Uniwersytet Gdański, Wydział Chemii

  15. Exposing unseen passages - towards identification of functional transient tunnels in protein structures

    Call: PRELUDIUM BIS 5 , Panel: NZ2

    Principal investigator: dr hab. Jan Brezovský

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  16. Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Emilia Aleksandra Sługocka

    Uniwersytet Jagielloński, Collegium Medicum

  17. MATTS-PDB The development of new Multipolar Atom Types from Theory and Statistical clustering (MATTS) data bank based on...

    Call: PRELUDIUM 22 , Panel: ST4

    Principal investigator: Paulina Maria Rybicka

    Uniwersytet Warszawski, Wydział Chemii

  18. Heme acquisition mechanisms of oral anaerobic Bacteroidetes members: from structure-function studies to development of b...

    Call: OPUS 25 , Panel: NZ6

    Principal investigator: prof. Teresa Barbara Olczak

    Uniwersytet Wrocławski, Wydział Biotechnologii

  19. Evolutionary-scale interpretation of protein functions in the human gut microbiome

    Call: WEAVE-UNISONO , Panel: NZ2

    Principal investigator: dr Tomasz Kościółek

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  20. Długie niekodujące RNA w ludzkich pluripotentnych komórkach macierzystych

    Call: OPUS 24 , Panel: NZ3

    Principal investigator: dr Marta Hanna Pabiś

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  21. Targeted inhibition of hypusination pathway

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: dr Przemysław Marek Grudnik

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  22. Biodiversity of bacteriophages: unusual DNA polymerases as exampels of surprising molecular diversity.

    Call: OPUS 23 , Panel: NZ1

    Principal investigator: prof. Alicja Beata Węgrzyn

    Uniwersytet Gdański

  23. Biological code of knots – identification of knotted patterns in biomolecules via AI approach

    Call: OPUS 22 (LAP) , Panel: NZ1

    Principal investigator: dr hab. Joanna Ida Sułkowska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  24. Tracing the fibrillation mechanism by nanospectroscopic profiling of structure-dependent tau protein aggregation

    Call: SONATA 17 , Panel: ST4

    Principal investigator: dr Kamila Sofińska

    Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  25. Close Encounters of the Third Kind: what happens when ribonuclease Dicer encounters in the cell RNA and DNA adopting G-q...

    Call: OPUS 21 , Panel: NZ2

    Principal investigator: dr hab. Anna Maria Kurzyńska-Kokorniak

    Instytut Chemii Bioorganicznej PAN

  26. Structure and Function of Protein Corona at the Nanoparticles Interface

    Call: OPUS 21 , Panel: ST5

    Principal investigator: prof. Barbara Dorota Jachimska

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  27. Data-assisted modeling of the ensemble structure of intrinsically disordered proteins and their assemblies

    Call: SHENG 2 , Panel: ST4

    Principal investigator: prof. Józef Adam Liwo

    Uniwersytet Gdański, Wydział Chemii

  28. High pressure studies of protein structure on the SOLCRYS beam line at the SOLARIS National Synchrotron Radiation Center

    Call: PRELUDIUM BIS 2 , Panel: ST4

    Principal investigator: prof. Maciej Leszek Kozak

    Uniwersytet Jagielloński, Narodowe Centrum Promieniowania Synchrotronowego SOLARIS

  29. The influence of environment on biomolecular function, structure and interactions.

    Call: SONATA BIS 10 , Panel: ST4

    Principal investigator: dr hab. Piotr Mikołaj Setny

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  30. Structure-function relationship in fibroblast growth factor signaling

    Call: CEUS-UNISONO , Panel: NZ3

    Principal investigator: dr hab. Małgorzata Urszula Zakrzewska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  31. Computational studies of the disulfide-bond role in proteins.

    Call: SONATA 15 , Panel: ST4

    Principal investigator: dr Paweł Krupa

    Instytut Fizyki PAN

  32. Identification and comprehensive classification of peptidases

    Call: SONATA 15 , Panel: NZ2

    Principal investigator: dr Kamil Steczkiewicz

    Instytut Biochemii i Biofizyki PAN

  33. Computational study of protein folding and dimerization on the ribosome

    Call: OPUS 18 , Panel: ST4

    Principal investigator: prof. Mai Suan Li

    Instytut Fizyki PAN

  34. CPL and RROA probes in the study of protein structure - induction of chirality and new methods of amplifying the chiropt...

    Call: OPUS 18 , Panel: ST4

    Principal investigator: dr Grzegorz Zając

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  35. Molecular and structural insights into human pseudouridine synthase 3

    Call: SONATA 15 , Panel: NZ1

    Principal investigator: dr Ting-Yu Lin

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  36. Novel methods for structural biology of large symmetric protein assemblies by solid-state Nuclear Magnetic Resonance (NM...

    Call: OPUS 17 , Panel: ST4

    Principal investigator: dr Jan Grzegorz Stanek

    Uniwersytet Warszawski, Wydział Chemii

  37. Advancing quantum crystallography for better insight into structure and properties of crystals

    Call: OPUS 16 , Panel: ST4

    Principal investigator: prof. Krzysztof Woźniak

    Uniwersytet Warszawski, Wydział Chemii

  38. Structure and function of a unique two-component system of periodontopathogenic bacteria Porphyromonas gingivalis

    Call: OPUS 16 , Panel: NZ1

    Principal investigator: prof. Jan Stanisław Potempa

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  39. Modeling of glycosaminoglycan-induced formation of protein structure and enhancement of biologically relevant protein-li...

    Call: SONATA BIS 8 , Panel: ST4

    Principal investigator: dr Sergey Samsonov

    Uniwersytet Gdański, Wydział Chemii

  40. Prediction of protein and peptide isoelectric point based on sequence and structure features

    Call: OPUS 15 , Panel: NZ2

    Principal investigator: dr Łukasz Paweł Kozłowski

    Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

  41. The roles of lncRNAs in alternative splicing regulation and modulation of chromatin structure

    Call: PRELUDIUM 14 , Panel: NZ1

    Principal investigator: Elżbieta Wanowska

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  42. Comprehensive research on enzymatic hydrolysis of native and chemically modified 5' RNA structures by Nudix protein fami...

    Call: OPUS 14 , Panel: NZ1

    Principal investigator: prof. Edward Darżynkiewicz

    Uniwersytet Warszawski, Wydział Fizyki

  43. An integrated approach to modeling protein structure and dynamics based on the UNRES coarse-grained force field and bioi...

    Call: HARMONIA 9 , Panel: ST4

    Principal investigator: dr hab. Cezary Ryszard Czaplewski

    Uniwersytet Gdański, Wydział Chemii

  44. Increasing global and local accuracy of the coarse-grained UNRES model of proteins and its extensions to simulating very...

    Call: OPUS 13 , Panel: ST4

    Principal investigator: prof. Józef Adam Liwo

    Uniwersytet Gdański, Wydział Chemii

  45. How RNA structure governs messenger RNA function? Exploring structural and functional aspects essential for synthesis of...

    Call: SONATA 12 , Panel: NZ1

    Principal investigator: dr Leszek Michał Błaszczyk

    Instytut Chemii Bioorganicznej PAN

  46. Influence of copper and membrane-mimicking environment on the structure of the human Prion Protein N-terminal domain

    Call: PRELUDIUM 12 , Panel: ST5

    Principal investigator: Aleksandra Anna Hecel-Czaplicka

    Uniwersytet Wrocławski, Wydział Chemii

  47. Structure and reactivity of proteins in the gas phase - a meeting between advanced mass spectrometry and molecular model...

    Call: HARMONIA 8 , Panel: ST4

    Principal investigator: dr Jarosław Jan Panek

    Uniwersytet Wrocławski, Wydział Chemii

  48. RNA structures and interactions with Gag protein that specify Ty1 RNA functions during retrotransposon replication

    Call: SONATA BIS 6 , Panel: NZ3

    Principal investigator: dr hab. Katarzyna Pachulska-Wieczorek

    Instytut Chemii Bioorganicznej PAN

  49. Structural studies of signaling receptors HVEM/CD160 as potential targets for immunoterapy against melanoma

    Call: SONATA 11 , Panel: NZ1

    Principal investigator: dr Marta Orlikowska

    Uniwersytet Gdański, Wydział Chemii

  50. Nanoscale Objects with Impossible Geometry

    Call: SYMFONIA 4 , Panel: NZ1

    Principal investigator: prof. Jonathan Gardiner Heddle

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

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