CPL and RROA probes in the study of protein structure - induction of chirality and new methods of amplifying the chiroptical signal

2019/35/B/ST4/04161

Keywords

Descriptors

  • ST4_002: Metody spektroskopowe i spektrometryczne
  • ST4_009: Chemia biologiczna
  • ST4_001: Chemia fizyczna, fizyka chemiczna

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Grzegorz Zając

Number of co-investigators in the project: 5

Call

OPUS 18 – announced on 2019-09-16

Amount awarded
1 453 332 PLN
Project start date
2020-07-06
Project end date
2025-12-05
Project duration
65 months (the same as in the proposal)
Project status
Project completed

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (5)

  1. Sulfhemoglobin under the spotlight – Detection and characterization of SHb and HbFeIII–SH

    Authors:
    Tetiana Stepanenko, Grzegorz Zając, Artur Czajkowski, Wiktoria Rutkowska, Andrzej Górecki, Katarzyna Maria Marzec, Jakub Dybas
    Academic press:
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (year: 2023, volume: 1870, pages: 119378), Publisher: Elsevier B.V.
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2022.119378 – link to the publication
  2. Recognition of the True and False Resonance Raman Optical Activity

    Authors:
    Ewa Machalska, Grzegorz Zajac, Aleksandra J. Wierzba, Josef Kapitán, Tadeusz Andruniów, Maciej Spiegel, Dorota Gryko, Petr Bouř, Malgorzata Baranska
    Academic press:
    Angewandte Chemie International Edition (year: 2021, volume: 60, pages: 21205-21210), Publisher: John Wiley & Sons, Inc.
    Status:
    Published
    DOI:
    10.1002/anie.202107600 – link to the publication
  3. Measurement and Theory of Resonance Raman Optical Activity for Gases, Liquids, and Aggregates. What It Tells about Molecules

    Authors:
    Grzegorz Zając, Petr Bouř
    Academic press:
    The Journal of Physical Chemistry B (year: 2022, volume: 126, pages: 355-367), Publisher: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.jpcb.1c08370 – link to the publication
  4. Why Does One Measure Resonance Raman Optical Activity? A Unique Case of Measurements under Strong Resonance versus Farfrom- Resonance Conditions

    Authors:
    Ewa Machalska, Monika Halat, Takumi Tani, Tomotsumi Fujisawa, Masashi Unno, Andrzej Kudelski, Malgorzata Baranska, Grzegorz Zając
    Academic press:
    The Journal of Physical Chemistry Letters (year: 2024, volume: 15, pages: 4913−4919), Publisher: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.jpclett.4c00270 – link to the publication
  5. Glutathione and its structural modifications recognized by Raman Optical Activity and Circularly Polarized Luminescence

    Authors:
    Agnieszka Domagała, Szymon Buda, Malgorzata Baranska, Grzegorz Zając
    Academic press:
    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy (year: 2025, volume: 324, pages: 124995), Publisher: Elsevier B.V.
    Status:
    Published
    DOI:
    10.1016/j.saa.2024.124995 – link to the publication

« New search

Graphic design and implementation: Jakub Piotrowski