Targeted inhibition of hypusination pathway
2022/47/B/NZ7/01667
Keywords
Descriptors
- NZ7_014: Farmacja, farmakoterapia, farmakologia
- NZ1_004: Biologia strukturalna
- NZ1_002: Biochemia
Panel
NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution
Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 5
Call
OPUS 24 – announced on 2022-07-15
- Amount awarded
- 2 999 196 PLN
- Project start date
- 2023-06-20
- Project end date
- 2027-08-19
- Project duration
- 50 months (the same as in the proposal)
- Project status
- Pending project
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (1)
-
ERK1/2 interaction with DHPS regulates eIF5A deoxyhypusination independently of ERK kinase activity
- Authors:
- Andrew E. Becker, Paweł Kochanowski, Pui-Kei Wu, Elżbieta Wątor, Wenjing Chen, Koushik Guchhait, Artur P. Biela, Przemysław Grudnik, Jong-In Park
- Academic press:
- Cell Reports (year: 2024, volume: 43, pages: 114831), Publisher: Cell Press
- Status:
- Published
- DOI:
- 10.1016/j.celrep.2024.114831 – link to the publication