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1. Aminophosphonates bearing fluorine atoms as inhibitors odf aminopeptideses and their potential application for determina…

Principal investigator: prof. Paweł Kazimierz Kafarski

Politechnika Wrocławska

Call: HARMONIA 9, Panel: ST5

2. Biomedical materials modification by proteolytic enzymes inhibitors

Principal investigator: prof. Anna Beata Jarosz-Wilkołazka

Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

Call: OPUS 13, Panel: NZ7

3. Design of high selective and safe juvenile hormone epoxide hydrolases inhibitors targeting selected pests based on the c…

Principal investigator: dr hab. Artur Wiktor Góra

Politechnika Śląska, Centrum Biotechnologii

Call: OPUS 20, Panel: ST4

4. Design and synthesis of probes for RabGGTase profiling and their application for identification of the site of phosphono…

Principal investigator: dr hab. Katarzyna Błażewska

Politechnika Łódzka, Wydział Chemiczny

Call: SONATA BIS 4, Panel: ST5

5. Chemical syntesis and evaluation of biochemical properties of 7-methyloguanosine 5'-diphosphate analogs as inhibitors of…

Principal investigator: Marcin Jarosław Ziemniak

Uniwersytet Warszawski, Wydział Fizyki

Call: PRELUDIUM 1, Panel: NZ1

6. Research on the influence of medicines of the angiotensin-converting enzyme inhibitors (ACEI) group on the choroidal and…

Principal investigator: Jowita Zwolska

Uniwersytet Przyrodniczy w Lublinie, Wydział Medycyny Weterynaryjnej

Call: PRELUDIUM 20, Panel: NZ4

7. Synthesis of 2-phosphonocarboxylates as potential covalent inhibitors of Rab geranylgeranyl transferase

Principal investigator: Joanna Natalia Małolepsza

Politechnika Łódzka, Wydział Chemiczny

Call: PRELUDIUM 12, Panel: ST5

8. Investigation of the molecular mechanisms of anti-leukemic activity of SK053, a small molecule compound targeting enzyme…

Principal investigator: prof. Dominika Anna Nowis

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: SONATA BIS 3, Panel: NZ5

9. Frog skin derived cyclic peptide as a molecular scaffold to create a novel tool for combining visualization and inhibiti…

Principal investigator: Aleksandra Dorota Helbik-Maciejewska

Uniwersytet Gdański

Call: PRELUDIUM 23, Panel: ST5

10. Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

Principal investigator: dr hab. Miłosz Ruszkowski

Instytut Chemii Bioorganicznej PAN

Call: SONATA BIS 13, Panel: NZ7

11. Development of a cell-based assay for screening of SARS-CoV-2 PLpro inhibitors

Principal investigator: dr Wioletta Katarzyna Rut-Schedlok

Politechnika Wrocławska

Call: SONATA 18, Panel: NZ6

12. Search for Inhibitors of Human δ1-Pyrroline-5-Carboxylate Reductase 1 (PYCR1) as Lead Molecules for the Development of N…

Principal investigator: dr hab. Miłosz Ruszkowski

Instytut Chemii Bioorganicznej PAN

Call: OPUS 22, Panel: NZ7

13. Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of en…

Principal investigator: prof. Mariusz Jaskólski

Instytut Chemii Bioorganicznej PAN

Call: OPUS 19, Panel: NZ1

14. CP protease of the O'nyong-nyong virus: substrate profiling, design and synthesis of inhibitors and activity-based probe…

Principal investigator: dr hab. Marcin Sieńczyk

Politechnika Wrocławska

Call: OPUS 15, Panel: NZ6

15. Structure and function characterization of newly discovered unique inhibitors of proteases

Principal investigator: prof. Jan Stanisław Potempa

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: OPUS 11, Panel: NZ1

16. Multicommutated bioanalytical systems for kinetic studies and enzyme activity assays

Principal investigator: prof. Robert Koncki

Uniwersytet Warszawski, Wydział Chemii

Call: OPUS 7, Panel: ST4

17. Crystallography of DNA repair enzymes as a tool to study substrate specifity and a mechanism of inhibition

Principal investigator: prof. Barbara Alicja Tudek

Instytut Biochemii i Biofizyki PAN

Call: HARMONIA 1, Panel: NZ1

18. Tick-borne encephalitis virus protease as a molecular target for novel inhibitors and activity-based probes

Principal investigator: dr Renata Grzywa

Politechnika Wrocławska

Call: OPUS 28, Panel: NZ6

19. Novel dual CYP17A1 and AKR1C3 inhibitors for studying the mechanism of resistance in prostate cancer

Principal investigator: dr hab. Tomasz Marcin Wróbel

Uniwersytet Medyczny w Lublinie

Call: SONATA 16, Panel: NZ7

20. Novel, rationally designed modulators of glycosomal import of enzymes in Trypanosoma parasites

Principal investigator: prof. Maciej Filip Dawidowski

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

Call: OPUS 16, Panel: NZ7

21. Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu…

Principal investigator: dr Magdalena Wujak

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

Call: OPUS 26, Panel: NZ7

22. Two-component preparations in the treatment of infections caused by pathogenic microorganisms

Principal investigator: dr Katarzyna Szałapata

Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

Call: SONATA 17, Panel: NZ7

23. Characterization of hydrolysates and peptides derived from oat kernels proteins in the context of their activity in dise…

Principal investigator: dr Monika Anna Pliszka

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Nauki o Żywności

Call: PRELUDIUM 16, Panel: NZ9

24. Search for structure-antimicrobial activity correlation for selected boraheterocycles

Principal investigator: prof. Sergiusz Mariusz Luliński

Politechnika Warszawska, Wydział Chemiczny

Call: OPUS 16, Panel: ST5

25. Development of method based on fluorescence polarization for high affinity ligand searching toward m7G nucleotide bindin…

Principal investigator: Anna Wojtczak

Uniwersytet Warszawski, Wydział Fizyki

Call: PRELUDIUM 11, Panel: ST4

26. Morita-Baylis-Hillman adducts as substrates in the synthesis of biologically active organophosphorus compounds

Principal investigator: dr hab. Artur Jacek Mucha

Politechnika Wrocławska, Wydział Chemiczny

Call: OPUS 5, Panel: ST5

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