Projects funded by the NCN

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21 projects found matching your search criteria :

  1. PIM kinases as rational therapeutic targets in lymphoid malignancies.

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr hab. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  2. Targeting of metabolic and transcriptomic cross-talk between leukemic cells and macrophages as a therapeutic strategy in...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Baran Natalia

    Instytut Hematologii i Transfuzjologii

  3. Mechanism of SYK-mediated suppression of differentiation and apoptosis in acute myeloid leukemia (AML)

    Call: PRELUDIUM 6 , Panel: NZ5

    Principal investigator: dr Anna Polak

    Instytut Hematologii i Transfuzjologii

  4. Expression, regulation and function of super-enhancer non-coding RNAs in Diffuse Large B-Cell Lymphoma (DLBCL)

    Call: PRELUDIUM 20 , Panel: NZ5

    Principal investigator: Sonia Dębek

    Instytut Hematologii i Transfuzjologii

  5. Identification and targeting molecular drug resistance mechanisms in adult B-cell acute lymphoblastic leukemia

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: dr hab. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  6. Mechanisms and consequences of CD19 loss in B-acute lymphoblastic leukaemia patients relapsing after CD19-CAR-T cell the...

    Call: PRELUDIUM BIS 3 , Panel: NZ5

    Principal investigator: prof. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  7. Identification and characterization of new epigenetic factors responsible for regulation of self-renewal in hematopoieti...

    Call: HARMONIA 10 , Panel: NZ3

    Principal investigator: dr Eliza Głodkowska-Mrówka

    Instytut Hematologii i Transfuzjologii

  8. The role of PIM kinases in the vascular niche of multiple myeloma

    Call: PRELUDIUM 16 , Panel: NZ5

    Principal investigator: Filip Garbicz

    Instytut Hematologii i Transfuzjologii

  9. Role of histone H3 serine 10 (H3S10) kinases in deregulation of transcription in diffuse large B-cell lymphoma

    Call: OPUS 15 , Panel: NZ5

    Principal investigator: prof. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  10. Inhibiting the Mitochondrial Intermembrane Space Assembly pathway as a newapproach to prevent metabolic reprogramming of...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr hab. Carlo Vascotto

    Instytut Hematologii i Transfuzjologii

  11. Actin cytoskeleton disorders as a pro-survival signaling activator and a therapeutic biomarker in Diffuse Large B-cell L...

    Call: SONATA BIS 13 , Panel: NZ5

    Principal investigator: dr Patryk Górniak

    Instytut Hematologii i Transfuzjologii

  12. Molecular mechanisms linking BRAF mutations and the expression of immunoregulatory molecules, galectin-1 and PD-L1 in me...

    Call: PRELUDIUM 8 , Panel: NZ5

    Principal investigator: Maja Wasylecka-Juszczyńska

    Instytut Hematologii i Transfuzjologii

  13. Gankyrin protein as a new potential therapeutic target in multiple myeloma

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: dr Irena Misiewicz-Krzemińska

    Instytut Hematologii i Transfuzjologii

  14. The proangiogenic functions of PIM kinases in plasma cell myeloma

    Call: ETIUDA 8 , Panel: NZ5

    Principal investigator: Filip Garbicz

    Instytut Hematologii i Transfuzjologii

  15. Significance of PIM-1 kinase mutations in progression of chronic lymphocytic leukemia

    Call: SONATA 11 , Panel: NZ5

    Principal investigator: dr Bartosz Puła

    Instytut Hematologii i Transfuzjologii

  16. Genetic features of Reed-Sternberg cells and their interplay with macrophages in classical Hodgkin lymphoma: identificat...

    Call: HARMONIA 8 , Panel: NZ5

    Principal investigator: prof. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  17. Role of PIM kinases in the biology of classical Hodgkin lymphoma tumor-associated macrophages

    Call: SONATA 13 , Panel: NZ5

    Principal investigator: dr Maciej Szydłowski

    Instytut Hematologii i Transfuzjologii

  18. Role of RelA(p65) and cRel phosphorylations and their kinases in the biology of Diffuse-large B-cell lymphoma and Hodgki...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Maciej Szydłowski

    Instytut Hematologii i Transfuzjologii

  19. Molecular mechanisms of DNA damage triggered by PIM kinases inhibition and its consequences for activation of innate imm...

    Call: OPUS 25 , Panel: NZ5

    Principal investigator: prof. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  20. Dynamina-2 jako potencjalny cel terapeutyczny w chłoniaku rozlanym z dużych komórek B

    Call: SONATA 15 , Panel: NZ5

    Principal investigator: dr Patryk Górniak

    Instytut Hematologii i Transfuzjologii

  21. Integrity of E3 ubiquitin ligase complex as a biomarker of response to treatment with immunomodulatory drugs in patients...

    Call: OPUS 7 , Panel: NZ5

    Principal investigator: dr hab. Ewa Lech-Marańda

    Instytut Hematologii i Transfuzjologii

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