Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Evolutionary genomics: Modeling and prediction of progression of breast and lung cancer

2021/41/B/NZ2/04134

Keywords:

mathematical modeling evolutionary genomics breast cancer lung cancer

Descriptors:

  • NZ2_002:
  • NZ2_008:
  • NZ2_010:

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Politechnika Śląska, Wydział Automatyki, Elektroniki i Informatyki

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Marek Kimmel 

Number of co-investigators in the project: 10

Call: OPUS 21 - announced on 2021-03-15

Amount awarded: 1 474 980 PLN

Project start date (Y-m-d): 2022-01-13

Project end date (Y-m-d): 2026-01-12

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (6)
  1. Mathematical modeling of regulatory networks of intracellular processes–Aims and selected methods
    Authors:
    Kardynska M., Kogut D., Pacholczyk M., Smieja J.
    Academic press:
    Computational and Structural Biotechnology Journal (rok: 2023, tom: 21, strony: 1523-1532), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.csbj.2023.02.006 - link to the publication
  2. Multiomics-Based Feature Extraction and Selection for the Prediction of Lung Cancer Survival
    Authors:
    Jaksik, R.; Szumała, K.; Dinh, K.N.; Śmieja, J.
    Academic press:
    International Journal of Molecular Sciences (rok: 2024, tom: 25(7), strony: 3661), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms25073661 - link to the publication
  3. Moran process version of the tug-of-war model: Behavior revealed by mathematical analysis and simulation studies
    Authors:
    Bobrowski A. Kimmel M., Kurpas M.K, Ratajczyk E.
    Academic press:
    Discrete and Continuous Dynamical Systems-B (rok: 2023, tom: 28(8), strony: 4532-4563), Wydawca: American Institute of Mathematical Sciences
    Status:
    Published
    DOI:
    10.3934/dcdsb.2023029 - link to the publication
  4. Occult metastases and survival of lung cancer by clinical diagnosis and CT screening: A simulation study.
    Authors:
    Chen X, Kanhar GM, Hu S, Wu C, Chao G, Jing M, Zhang F, Young M, Kimmel M, Chen L, Gorlova OY
    Academic press:
    PLoS One (rok: 2025, tom: 20(1), strony: e0313544), Wydawca: PLoS One
    Status:
    Published
    DOI:
    10.1371/journal.pone.0313544 - link to the publication
  5. Modes of Selection in Tumors as Reflected by Two Mathematical Models and Site Frequency Spectra
    Authors:
    Kurpas M. K., Kimmel M.
    Academic press:
    Frontiers in Ecology and Evolution (rok: 2022, tom: 10, strony: 45678), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fevo.2022.889438 - link to the publication
  6. Genomic Analysis of SARS-CoV-2 Alpha, Beta and Delta Variants of Concern Uncovers Signatures of Neutral and Non-Neutral Evolution
    Authors:
    Kurpas M.K., Jaksik R., Kuś P., Kimmel M.
    Academic press:
    Viruses (rok: 2022, tom: 14(11), strony: 2375), Wydawca: MDPI AG
    Status:
    Published
    DOI:
    10.3390/v14112375 - link to the publication

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