Projects funded by the NCN

Campylobacter jejuni protein expression, stress response and virulence modulated by methylation of 16S rRNA nucleotide C...

Call: PRELUDIUM 24 , Panel: NZ6

Principal investigator: Małgorzata Sylwia Murawska

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie

The history of Balts from the area of present-day north-eastern Poland during the Iron Age and the Middle Ages based on ...

Call: PRELUDIUM 23 , Panel: HS3

Principal investigator: Michał Ireneusz Golubiński

Uniwersytet Warszawski

Genomic analysis of invasive vancomycin-resistant Enterococcus faecium of VanA phenotype from intensive-care units in Po...

Call: SONATA 19 , Panel: NZ7

Principal investigator: dr Ewa Nina Wardal

Narodowy Instytut Leków

Functional and structural relationship between nucleotide sugar biosynthesis and their transport to the subcellular comp...

Call: OPUS 26 , Panel: NZ3

Principal investigator: prof. Mariusz Olczak

Uniwersytet Wrocławski, Wydział Biotechnologii

Plasmonic nanoparticles decorated with fluorescently-labelled mRNA: using single-pair FRET effect for investigating enzy...

Call: OPUS 25 , Panel: ST4

Principal investigator: prof. Joanna Niedziółka-Jönsson

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Feel the chemistry if you're close enough - proximity-induced SuFEx ligation for mRNA biology and medicine

Call: OPUS 25 , Panel: ST5

Principal investigator: prof. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Modified (oligo)nucleotides for photo-controlled manipulation of mRNA

Call: SONATA 18 , Panel: ST4

Principal investigator: dr Marcin Warmiński

Uniwersytet Warszawski, Wydział Fizyki

Algorithms for processing nucleotide and aminoacid sequences

Call: OPUS 23 , Panel: ST6

Principal investigator: prof. Sebastian Tomasz Deorowicz

Politechnika Śląska, Wydział Automatyki, Elektroniki i Informatyki

A rare Single Nucleotide Polymorphism in human WDR61 used to identify a novel complex associated with SF3A/B component o...

Call: OPUS 23 , Panel: NZ1

Principal investigator: dr Agnieszka Irena Tudek

Instytut Biochemii i Biofizyki PAN

The characteristic of fucose metabolism in mammalian cells

Call: PRELUDIUM 21 , Panel: NZ3

Principal investigator: Edyta Skurska

Uniwersytet Wrocławski, Wydział Biotechnologii

Molecular Analysis of Abiotic Stress Tolerance in Finger Millet: Improving a Climate Resilient Crop for Food and Nutriti...

Call: POLONEZ BIS 2 , Panel: NZ2

Principal investigator: dr Edossa Fikiru Wayima

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Novel pathway of vitamin B12 activation by CD73 - analysis of molecular mechanisms, in vivo processing and clinical rele...

Call: SONATA 17 , Panel: NZ4

Principal investigator: dr hab. Marta Urszula Tomczyk

Gdański Uniwersytet Medyczny, Wydział Lekarski

Radiosensitization by the combined use of modified nucleosides and inhibitors of DNA repair to improve the efficacy of r...

Call: SONATA 17 , Panel: ST4

Principal investigator: dr Magdalena Danuta Zdrowowicz-Żamojć

Uniwersytet Gdański, Wydział Chemii

Synthesis and structural/biophysical studies of model mRNA/mt-tRNA oligomers to evaluate the role of modified nucleoside...

Call: OPUS 22 , Panel: ST4

Principal investigator: dr hab. Grażyna Bożena Leszczyńska

Politechnika Łódzka

Genetic and epigenetic fundamentals of cerebral vasospasm after aneurysmal subarachnoid hemorrhage

Call: PRELUDIUM 20 , Panel: NZ2

Principal investigator: Tomasz Klepinowski

Pomorski Uniwersytet Medyczny w Szczecinie

Nucleotide sugar transporters as organizing centers of glycosylation-related macromolecular complexes

Call: OPUS 20 , Panel: NZ3

Principal investigator: dr Dorota Justyna Maszczak-Seneczko

Uniwersytet Wrocławski, Wydział Biotechnologii

Genetic variation of Scots pine ecotypes in Poland and its evolutionary and forest management implications following env...

Call: OPUS 19 , Panel: NZ9

Principal investigator: prof. Witold Marcin Wachowiak

Instytut Dendrologii PAN

Chemical architecture of fluorinated nucleoside dimers containing 1,2,3-triazole linker of potential use in molecular bi...

Call: SONATA 15 , Panel: NZ7

Principal investigator: dr Dagmara Baraniak

Instytut Chemii Bioorganicznej PAN

Hsp70 and its cochaperones in protein recovery from aggregates

Call: OPUS 18 , Panel: NZ1

Principal investigator: prof. Krzysztof Piotr Liberek

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

The use of evolutionary patterns in the optimization of chemotherapy of tuberculosis

Call: SONATA BIS 9 , Panel: NZ6

Principal investigator: dr Alina Ewa Minias

Instytut Biologii Medycznej PAN

mRNA 5' end methylation status: towards deeper understanding of biological role and identification of synthetic mimics

Call: OPUS 17 , Panel: ST4

Principal investigator: prof. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Fotochemistry and Photophysics of Thiated Prebiotic Precursors of Nucleotides

Call: PRELUDIUM 17 , Panel: ST4

Principal investigator: dr Mikołaj Jan Janicki

Politechnika Wrocławska

Spatio-temporal dynamics of genome-wide diversity of Fagus sylvatica

Call: BEETHOVEN LIFE 1 , Panel: NZ2

Principal investigator: prof. Jarosław Burczyk

Uniwersytet Kazimierza Wielkiego, Wydział Nauk Przyrodniczych

Exploring second generation of nucleotide analogues containing phosphoranesulfen- or phosphoraneselenamides as new struc...

Call: PRELUDIUM 16 , Panel: ST5

Principal investigator: dr Justyna Gołębiewska

Instytut Chemii Bioorganicznej PAN

Synthesis and characterization of new molecular probes for monitoring activity of enzymes associated with RNA decapping ...

Call: OPUS 16 , Panel: ST5

Principal investigator: dr hab. Joanna Kowalska

Uniwersytet Warszawski, Wydział Fizyki

Biochemical bases of ectopic calcification of skeletal muscles in animal model of Duchenne muscular dystrophy (mdx mice)

Call: OPUS 15 , Panel: NZ4

Principal investigator: prof. Krzysztof Olaf Zabłocki

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Application of targeted metabolomic approach in quantitative prospective analysis of nucleosides profiles alterations be...

Call: PRELUDIUM 15 , Panel: NZ7

Principal investigator: Małgorzata Artymowicz

Gdański Uniwersytet Medyczny

Why Nature introduced selenium to wobble nucleosides in transfer RNA?

Call: OPUS 15 , Panel: ST5

Principal investigator: prof. Barbara Czesława Nawrot

Centrum Badań Molekularnych i Makromolekularnych PAN

Purinergic signaling as important regulator of hematopoietic system

Call: OPUS 15 , Panel: NZ4

Principal investigator: prof. Mariusz Zdzisław Ratajczak

Warszawski Uniwersytet Medyczny, Wydział Lekarski

Functional glycol nucleic acid (fun-GNA) nucleosides, nucleotides and oligos: synthesis and properties

Call: OPUS 15 , Panel: ST5

Principal investigator: prof. Konrad Maciej Kowalski

Uniwersytet Łódzki, Wydział Chemii

Revision of migration-selection patterns in Scots pine (Pinus sylvestris L.) using novel genomic approaches.

Call: OPUS 14 , Panel: NZ9

Principal investigator: prof. Witold Marcin Wachowiak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Analysis of cooperation of SLC35A3, SLC35B4 and SLC35D2 proteins in UDP-N-acetylglucosamine distribution in mammalian ce...

Call: PRELUDIUM 14 , Panel: NZ3

Principal investigator: Bożena Szulc

Uniwersytet Wrocławski, Wydział Biotechnologii

The role of extracellular ATP fraction in induction of epithelial-mesenchymal transition - studies using analogs of nucl...

Call: SONATA 13 , Panel: ST5

Principal investigator: dr Róża Jadwiga Pawłowska

Centrum Badań Molekularnych i Makromolekularnych PAN

Synthesis of trimethyl cap analogs modified with molecular rotors and their application in nuclear transport studies

Call: SONATA 13 , Panel: ST5

Principal investigator: dr Błażej Wojtczak

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Structural and mechanistic studies of bacterial DNA repair

Call: MAESTRO 9 , Panel: NZ1

Principal investigator: dr hab. Marcin Piotr Nowotny

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

The influence of impairment of extracellular nucleoside and nucleotide signaling on synaptic structure and function in a...

Call: OPUS 13 , Panel: NZ4

Principal investigator: dr hab. Agata Adamczyk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Synthesis and structural studies of oligonucleotides with tRNA anticodon stem-loop sequences containing newly discovered...

Call: OPUS 13 , Panel: ST5

Principal investigator: prof. Elżbieta Jadwiga Sochacka

Politechnika Łódzka, Wydział Chemiczny

Investigating the biological role of 5' nucleotidases cN-IIIA and cN-IIIB in mRNA degradation and their terapeutic signi...

Call: SONATINA 1 , Panel: NZ1

Principal investigator: dr Dorota Maria Kubacka

Uniwersytet Warszawski, Wydział Fizyki

Adaptations of cardiac myocyte energy metabolism in atherosclerosis - implications for pathology and therapeutic strateg...

Call: OPUS 12 , Panel: NZ4

Principal investigator: dr hab. Ryszard Tomasz Smoleński

Gdański Uniwersytet Medyczny, Wydział Lekarski

Development of HTS method based on fluorescently labelled guanosine analogues: novel route for RNA (guanosine-N7)-methyl...

Call: PRELUDIUM 12 , Panel: ST4

Principal investigator: Renata Kasprzyk

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Application of LCMS to quantitative analysis of composition of in vitro transcribed RNAs containing chemically modified ...

Call: PRELUDIUM 12 , Panel: ST4

Principal investigator: Dominika Strzelecka

Uniwersytet Warszawski, Wydział Fizyki

N-Oxide phosphobetaines in new synthetic strategies for P-modified phosphates and polyphospates of natural biomolecules ...

Call: PRELUDIUM 12 , Panel: ST5

Principal investigator: Magdalena Materna

Instytut Chemii Bioorganicznej PAN

In search of novel functions for SLC35A2 protein

Call: SONATA 12 , Panel: NZ3

Principal investigator: dr Dorota Justyna Maszczak-Seneczko

Uniwersytet Wrocławski, Wydział Biotechnologii

Reversal of heart failure during mechanical support of left ventricular function - role of nucleotides and energetics in...

Call: HARMONIA 8 , Panel: NZ4

Principal investigator: dr hab. Ryszard Tomasz Smoleński

Gdański Uniwersytet Medyczny, Wydział Lekarski

Determination of the influence of 5' end of RNA modifications and nucleotide or amino acid sequence on the electrostatic...

Call: PRELUDIUM 11 , Panel: ST4

Principal investigator: Urszula Anna Budniak

Uniwersytet Warszawski, Wydział Chemii

Development of method based on fluorescence polarization for high affinity ligand searching toward m7G nucleotide bindin...

Call: PRELUDIUM 11 , Panel: ST4

Principal investigator: Anna Wojtczak

Uniwersytet Warszawski, Wydział Fizyki

Chemically modified mRNA for studies on cellular processes and therapeutic applications

Call: OPUS 11 , Panel: ST5

Principal investigator: prof. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Fluorescent biosensors based on quantum dots and purines/pyrimidines - synthesis, characterization and potential applica...

Call: PRELUDIUM 11 , Panel: ST5

Principal investigator: Łucja Anna Rodzik-Czałka

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Molecular bases of a therapy of rare genetic diseases caused by impaired activity of nucleotide sugar transporters

Call: OPUS 11 , Panel: NZ5

Principal investigator: prof. Mariusz Olczak

Uniwersytet Wrocławski, Wydział Biotechnologii

Pro-nucleotides based on mRNA cap structure - synthesis, biological and biophysical evaluation

Call: SONATA 11 , Panel: ST5

Principal investigator: dr Karolina Ewa Piecyk

Uniwersytet Warszawski, Wydział Chemii