Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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In search of novel functions for SLC35A2 protein

2016/23/D/NZ3/01314

Keywords:

nucleotide sugar transporters glycosyltransferases Golgi apparatus protein complexes secretory pathway cytoskeleton endocytosis mitochondria

Descriptors:

  • NZ3_1: Cell biology
  • NZ3_2: Cell physiology
  • NZ1_2: Biochemistry

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Wrocławski, Wydział Biotechnologii

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Dorota Maszczak-Seneczko 

Number of co-investigators in the project: 6

Call: SONATA 12 - announced on 2016-09-15

Amount awarded: 659 000 PLN

Project start date (Y-m-d): 2017-07-27

Project end date (Y-m-d): 2021-07-26

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Zamrażarka niskotemperaturowa (-80 stopni Celsjusza) (28 000 PLN)
  2. Wirówka stołowa (7 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. N-glycosylation of the human β1,4-galactosyltransferase 4 is crucial for its activity and Golgi localization
    Authors:
    Auhen Shauchuk, Bożena Szulc, Dorota Maszczak-Seneczko, Wojciech Wiertelak, Edyta Skurska, Mariusz Olczak
    Academic press:
    Glycoconjugate Journal (rok: 2020, tom: 5, strony: 577-588), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10719-020-09941-z - link to the publication
  2. SLC35A2 Deficiency Promotes an Epithelial-to-Mesenchymal Transition-like Phenotype in Madin-Darby Canine Kidney Cells
    Authors:
    Magdalena Kot, Ewa Mazurkiewicz, Maciej Wiktor, Wojciech Wiertelak, Antonina Joanna Mazur, Andrei Rahalevich, Mariusz Olczak, Dorota Maszczak-Seneczko
    Academic press:
    Cells (rok: 2022, tom: 11, strony: 2273), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells11152273 - link to the publication
  3. Analysis of homologous and heterologous interactions between UDP-galactose transporter and beta-1,4-galactosyltransferase 1 using NanoBiT
    Authors:
    Wojciech Wiertelak, Paulina Sosicka, Mariusz Olczak, Dorota Maszczak-Seneczko
    Academic press:
    Analytical Biochemistry (rok: 2020, tom: 593, strony: 113599), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ab.2020.113599 - link to the publication
  4. Demonstration of Heterologous Complexes formed by Golgi-Resident Type III Membrane Proteins using Split Luciferase Complementation Assay
    Authors:
    Wojciech Wiertelak, Mariusz Olczak, Dorota Maszczak-Seneczko
    Academic press:
    Journal of Visualized Experiments (rok: 2020, tom: 163, strony: e61669), Wydawca: MyJove Corp.
    Status:
    Published
    DOI:
    10.3791/61669 - link to the publication
  5. Identification of novel potential interaction partners of UDP-galactose (SLC35A2), UDP-N-acetylglucosamine (SLC35A3) and an orphan (SLC35A4) nucleotide sugar transporters
    Authors:
    Maciej Wiktor, Wojciech Wiertelak, Dorota Maszczak-Seneczko, Piotr Jan Balwierz, Bożena Szulc, Mariusz Olczak
    Academic press:
    Journal of Proteomics (rok: 2021, tom: 249, strony: 104321), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jprot.2021.104321 - link to the publication

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