Projects funded by the NCN

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100 projects found matching your search criteria :

  1. New nucleotide analogs containing triazole within oligophosphate bridge as mimics of the 5' end of mRNA - synthesis, pro...

    Call: PRELUDIUM 9 , Panel: ST5

    Principal investigator: Sylwia Ciechanowicz

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  2. Chromosome topolgy as a global regulator of gene transcription - interplay between topoisomerases and nucleoid binding p...

    Call: OPUS 8 , Panel: NZ2

    Principal investigator: dr hab. Dagmara Jakimowicz

    Uniwersytet Wrocławski, Wydział Biotechnologii

  3. Functional analysis of SLC35A transporter family - substrate specificity and ability to interact with other proteins in ...

    Call: OPUS 8 , Panel: NZ3

    Principal investigator: prof. Mariusz Olczak

    Uniwersytet Wrocławski, Wydział Biotechnologii

  4. Characteristics of nucleotide sugar transporters SLC35A4 and SLC35A5

    Call: PRELUDIUM 8 , Panel: NZ1

    Principal investigator: Paulina Sosicka

    Uniwersytet Wrocławski, Wydział Biotechnologii

  5. Chemical syntesis and evaluation of biochemical properties of 7-methyloguanosine 5'-diphosphate analogs as inhibitors of...

    Call: PRELUDIUM 1 , Panel: NZ1

    Principal investigator: Marcin Ziemniak

    Uniwersytet Warszawski, Wydział Fizyki

  6. From a molecular in silico model to cellular response in vitro. Modified nucleosides as photo and/or radiosensitizers of...

    Call: MAESTRO 6 , Panel: ST4

    Principal investigator: prof. Janusz Rak

    Uniwersytet Gdański, Wydział Chemii

  7. THE EFFECT OF NUCLEOSIDE ANALOGUES ON REPLICATION OF CYHV-3 (CYPRINID HERPESVIRUS 3) IN CELL LINES OF COMMON CARP (CYPRI...

    Call: PRELUDIUM 7 , Panel: NZ6

    Principal investigator: Agnieszka Troszok

    Polska Akademia Nauk Zakład Ichtiobiologii i Gospodarki Rybackiej w Gołyszu

  8. Studies on the synthesis of newly discovered cyclic N6-threonylcarbamoyladenosine (ct6A) and its analogues and on the in...

    Call: PRELUDIUM 7 , Panel: ST5

    Principal investigator: Michał Matuszewski

    Politechnika Łódzka, Wydział Chemiczny

  9. Metabolic profiles, gene polymorphism in NAT2, GSTM1, GSTP1, CYP1A1, COMT and epidemiological data in a holistic approac...

    Call: PRELUDIUM 7 , Panel: NZ7

    Principal investigator: Emilia Daghir-Wojtkowiak

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  10. Biosynthesis of seleno-modified nucleosides in the anticodon loop of transfer ribonucleic acids. Evaluation of the enzym...

    Call: OPUS 7 , Panel: ST5

    Principal investigator: prof. Barbara Nawrot

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  11. Methods and algorithms of discovering novel phenomena in genomes and transcriptomes with the statistical analysis of nuc...

    Call: PRELUDIUM 7 , Panel: ST6

    Principal investigator: Marek Wiewiórka

    Politechnika Warszawska, Wydział Elektroniki i Technik Informacyjnych

  12. Cellular and molecular mechanism of action of PPI dendrimer complexes with nucleoside analogue anticancer drugs

    Call: OPUS 7 , Panel: NZ3

    Principal investigator: prof. Barbara Klajnert-Maculewicz

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  13. Abnormal metabotropic-nucleotide-receptors (P2Y) - dependent calcium response in myoblasts derived from mouse with mutat...

    Call: OPUS 6 , Panel: NZ3

    Principal investigator: prof. Krzysztof Zabłocki

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  14. New gamma-lactam analogues of homo-N-nucleosides

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Joanna Gotkowska

    Uniwersytet Medyczny w Łodzi, Katedra Chemii Bioorganicznej i Biokoordynacyjnej

  15. Synthesis, biological and biophysical evaluation of mRNA cap-peptide conjugates for targeted delivery of cap analogues t...

    Call: OPUS 6 , Panel: ST5

    Principal investigator: dr hab. Marzena Jankowska-Anyszka

    Uniwersytet Warszawski, Wydział Chemii

  16. Thermodynamic insights into design of functionally optimized modified siRNAs and their experimental verification.

    Call: SONATA BIS 3 , Panel: NZ1

    Principal investigator: dr hab. Anna Pasternak

    Instytut Chemii Bioorganicznej PAN

  17. Isosterically modified acyclic nucleoside phosphonates

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: prof. Andrzej Wróblewski

    Uniwersytet Medyczny w Łodzi, Wydział Farmaceutyczny

  18. The effect of long-term physical training on changes in the metabolism of nucleotides and their derivatives in blood.

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: dr hab. Jacek Zieliński

    Akademia Wychowania Fizycznego im. Eugeniusza Piaseckiego w Poznaniu, Wydział Wychowania Fizycznego, Sportu i Rehabilitacji

  19. New methods for mRNA 5' end labeling and examples of their application in studies on RNA metabolism and searching for in...

    Call: OPUS 5 , Panel: ST5

    Principal investigator: dr hab. Jacek Jemielity

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  20. Transformation of 5'-O-monothiophosphate nucleoside to 5'-O-monophosphate in the cell - possible metabolism of phosphoro...

    Call: OPUS 5 , Panel: ST5

    Principal investigator: dr Agnieszka Krakowiak

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  21. Synthesis and study of spectroscopic and bilogical properties of nucleosides modyfied by new stilbene derivatives

    Call: OPUS 4 , Panel: ST5

    Principal investigator: dr hab. Przemysław Szczeciński

    Politechnika Warszawska, Wydział Chemiczny

  22. Regulation of Expression of Ecto-5'-Nucleotidase - Changes in Pathology and Therapeutic Potential

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: dr hab. Ryszard Smoleński

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  23. An assessment of the relationship between the risk of stroke and the single nucleotide polymorphizm in the genome - wide...

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: prof. Krzysztof Ziaja

    Śląski Uniwersytet Medyczny

  24. Pronucloetides - a pathway to cellular DNA sensitization to ionizing radiation

    Call: PRELUDIUM 4 , Panel: ST5

    Principal investigator: Magdalena Zdrowowicz

    Uniwersytet Gdański, Wydział Chemii

  25. Development of chemical method for synthesis of biologically active triphosphates using thermolabile protecting groups

    Call: OPUS 4 , Panel: ST5

    Principal investigator: dr hab. Marcin Chmielewski

    Instytut Chemii Bioorganicznej PAN

  26. The impact of rs868 single nucleotide polymorphism on the outcome of liver transplantation in hepatitis C

    Call: PRELUDIUM 3 , Panel: NZ6

    Principal investigator: Emir Sajjad

    Warszawski Uniwersytet Medyczny, I Wydział Lekarski

  27. New 3,8-disubstituted purine nucleoside analogues as prospective application for research of structure and biological ac...

    Call: SONATA 3 , Panel: ST5

    Principal investigator: dr hab. Anna Pasternak

    Instytut Chemii Bioorganicznej PAN

  28. Influence of nucleotide sequence on the yield of radio- and photodamage to double stranded DNA fragments labelled with t...

    Call: OPUS 3 , Panel: ST5

    Principal investigator: prof. Janusz Rak

    Uniwersytet Gdański, Wydział Chemii

  29. Pirymidine phosphorothioate analogues of nucleotides as multifunctional regulators of P2Y6 and P2Y14 nucleotide receptor...

    Call: PRELUDIUM 3 , Panel: NZ5

    Principal investigator: Edyta Węgłowska

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  30. Functional analyses of single nucleotide polymorphisms, rs10814948/9p24.2 and rs6702619/1p21.1, associating with colorec...

    Call: PRELUDIUM 3 , Panel: NZ2

    Principal investigator: Natalia Maryan

    Centrum Medyczne Kształcenia Podyplomowego

  31. Adenosine 5'-phosphoramidate as a novel signaling molecule; Study of enzymatic synthesis of this nucleotide and analysis...

    Call: OPUS 3 , Panel: NZ1

    Principal investigator: prof. Andrzej Guranowski

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa i Bioinżynierii

  32. New reagents and methods in synthesis of modified nucleotides and their application for preparation biochemical tools an...

    Call: SONATA BIS 1 , Panel: ST5

    Principal investigator: dr hab. Jacek Jemielity

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  33. Phylogeography and population genomics of the red fox, Vulpes vulpes

    Call: OPUS 3 , Panel: NZ8

    Principal investigator: prof. Jan Wójcik

    Instytut Biologii Ssaków Polskiej Akademii Nauk

  34. Conjugates of cap analogs with nanomaterials and biomolecules with potential applications in pharmacology or diagnostics

    Call: SONATA 1 , Panel: ST5

    Principal investigator: dr Joanna Kowalska

    Uniwersytet Warszawski, Wydział Fizyki

  35. Association genetics of nucleotide polymorphisms related to adaptive variation and population history in the European ra...

    Call: SONATA BIS 1 , Panel: NZ9

    Principal investigator: dr hab. Witold Wachowiak

    Instytut Dendrologii PAN

  36. Genomics of adaptation in oak and beech, as model forest tree species

    Call: MAESTRO 2 , Panel: NZ9

    Principal investigator: prof. Jarosław Burczyk

    Uniwersytet Kazimierza Wielkiego, Wydział Nauk Przyrodniczych

  37. Stereodefined phosphorothioate analogs of DNA with incorporated LNA-type nucleosides - synthesis and properties of compl...

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr hab. Piotr Guga

    Centrum Badań Molekularnych i Makromolekularnych PAN

  38. Genomic analysis of invasive vancomycin-resistant Enterococcus faecium of VanA phenotype from intensive-care units in Po...

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Ewa Wardal

    Narodowy Instytut Leków

  39. Targeting enzymes of the parasite's purine salvage pathway as a new approach to combat H. pylori infections, including t...

    Call: OPUS 26 , Panel: NZ1

    Principal investigator: prof. Maria Bzowska

    Uniwersytet Warszawski, Wydział Fizyki

  40. Functional and structural relationship between nucleotide sugar biosynthesis and their transport to the subcellular comp...

    Call: OPUS 26 , Panel: NZ3

    Principal investigator: prof. Mariusz Olczak

    Uniwersytet Wrocławski, Wydział Biotechnologii

  41. Plasmonic nanoparticles decorated with fluorescently-labelled mRNA: using single-pair FRET effect for investigating enzy...

    Call: OPUS 25 , Panel: ST4

    Principal investigator: prof. Joanna Niedziółka-Jönsson

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  42. The interplay between nucleoid associated proteins and transcription factors at regulation of gene expression in antibio...

    Call: OPUS 25 , Panel: NZ2

    Principal investigator: prof. Dagmara Jakimowicz

    Uniwersytet Wrocławski, Wydział Biotechnologii

  43. Feel the chemistry if you're close enough - proximity-induced SuFEx ligation for mRNA biology and medicine

    Call: OPUS 25 , Panel: ST5

    Principal investigator: prof. Jacek Jemielity

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  44. Modified (oligo)nucleotides for photo-controlled manipulation of mRNA

    Call: SONATA 18 , Panel: ST4

    Principal investigator: dr Marcin Warmiński

    Uniwersytet Warszawski, Wydział Fizyki

  45. Algorithms for processing nucleotide and aminoacid sequences

    Call: OPUS 23 , Panel: ST6

    Principal investigator: prof. Sebastian Deorowicz

    Politechnika Śląska, Wydział Automatyki, Elektroniki i Informatyki

  46. A rare Single Nucleotide Polymorphism in human WDR61 used to identify a novel complex associated with SF3A/B component o...

    Call: OPUS 23 , Panel: NZ1

    Principal investigator: dr Agnieszka Tudek

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  47. The characteristic of fucose metabolism in mammalian cells

    Call: PRELUDIUM 21 , Panel: NZ3

    Principal investigator: Edyta Skurska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  48. Molecular Analysis of Abiotic Stress Tolerance in Finger Millet: Improving a Climate Resilient Crop for Food and Nutriti...

    Call: POLONEZ BIS 2 , Panel: NZ2

    Principal investigator: dr Edossa Fikiru Wayima

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  49. Novel pathway of vitamin B12 activation by CD73 - analysis of molecular mechanisms, in vivo processing and clinical rele...

    Call: SONATA 17 , Panel: NZ4

    Principal investigator: dr Marta Tomczyk

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  50. Radiosensitization by the combined use of modified nucleosides and inhibitors of DNA repair to improve the efficacy of r...

    Call: SONATA 17 , Panel: ST4

    Principal investigator: dr Magdalena Zdrowowicz-Żamojć

    Uniwersytet Gdański, Wydział Chemii

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