Projects funded by the NCN

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100 projects found matching your search criteria :

  1. Simultaneous stimulation of muscarinic M4 receptor and selected receptors involved in the regulation of glutamate releas...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: dr hab. Joanna Wierońska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  2. Synthesis of novel receptors, their application in chiral recognition of biologically relevant anions, and development o...

    Call: OPUS 8 , Panel: ST5

    Principal investigator: prof. Janusz Jurczak

    Instytut Chemii Organicznej PAN

  3. Non-quinazoline antagonists of apha1 and 5-HT2A receptors with pleiotropic effects as a new perspective for hypertension...

    Call: SONATA 8 , Panel: NZ7

    Principal investigator: dr Monika Kubacka

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  4. New selective antagonists of ionotropic glutamate non-NMDA receptors

    Call: OPUS 8 , Panel: NZ7

    Principal investigator: dr Ewa Szymańska

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  5. The new homology model of H3 histaminic receptor - structure, interaction with ligand

    Call: PRELUDIUM 8 , Panel: NZ7

    Principal investigator: Jakub Jończyk

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  6. Novel polyelectrolytes as potential inhibitors of HSV-1 virus - synthesis, properties and mechanism of action

    Call: OPUS 7 , Panel: ST5

    Principal investigator: prof. Maria Nowakowska

    Uniwersytet Jagielloński, Wydział Chemii

  7. Targeting peripheral cannabinoid receptors CB2 as a novel therapy to treat osteoarthritis

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Starowicz-Bubak

    INSTYTUT FARMAKOLOGII PAN

  8. Stearoyl-CoA desaturase and intracellular lipid signaling as novel players in regulation of thyroid hormone action in th...

    Call: OPUS 7 , Panel: NZ4

    Principal investigator: dr hab. Paweł Dobrzyń

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  9. Novel type modulators of purinergic receptors - Synthesis and study of receptor-ligand interaction

    Call: OPUS 7 , Panel: NZ1

    Principal investigator: prof. Zbigniew Leśnikowski

    Instytut Biologii Medycznej PAN

  10. Synthesis and marking the activity of new potential antagonists of receptors for excitatory amino acids which have the s...

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: prof. Aleksander Mazurek

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

  11. A comparative evaluation of effectiveness of phosphorothioate and phosphodiester lysophosphatidylcholine analogues in re...

    Call: PRELUDIUM 6 , Panel: NZ5

    Principal investigator: Anna Drzazga

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  12. The role of sphingosine-1-phosphate (S1P) receptors signaling in animal model of Parkinson disease. Searching of novel t...

    Call: PRELUDIUM 5 , Panel: NZ4

    Principal investigator: Joanna Motyl

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  13. Identification and characterization of the new receptors for Salmonella enterica and its role in pathogenesis and Salmon...

    Call: SONATA 5 , Panel: NZ6

    Principal investigator: dr Krzysztof Grzymajło

    Uniwersytet Przyrodniczy we Wrocławiu, Wydział Medycyny Weterynaryjnej

  14. Analysis of the structural and functional mechanisms of action of the nicotinic receptors modulators.

    Call: SONATA 5 , Panel: NZ7

    Principal investigator: dr Katarzyna Targowska-Duda

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

  15. Obtaining of new quinoline derivatives with potential activity for serotonin receptors and inhibition of serotonin reupt...

    Call: PRELUDIUM 5 , Panel: NZ7

    Principal investigator: Przemysław Taciak

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  16. Novel C3 symmetric triptycene derivatives useful for construction of artificial anion receptors

    Call: PRELUDIUM 4 , Panel: ST5

    Principal investigator: dr Jarosław Granda

    Instytut Chemii Organicznej PAN

  17. PHARMACOTHERAPY OF OSTEOARTHRITIS: TRPV1 AND CB1 RECEPTORS AND THEIR ENDOGENOUS LIGANDS AS NEW TARGETS FOR PHARMACOLOGIC...

    Call: SONATA BIS 2 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Starowicz-Bubak

    Instytut Farmakologii PAN

  18. Henryk Sienkiewicz. Presence in 20th century Polish culture. Reception and new readings.

    Call: MAESTRO 3 , Panel: HS2

    Principal investigator: prof. Tadeusz Bujnicki

    Uniwersytet Warszawski, Wydział "Artes Liberales"

  19. The study of the role of mGluR8 in cancer cells - a potential target for new antitumor strategies

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr Danuta Jantas

    Instytut Farmakologii PAN

  20. Identification of mechanisms responsible for calcium homeostasis deregulation and concomitant disturbances in GABA metab...

    Call: SONATA 3 , Panel: NZ4

    Principal investigator: dr Tomasz Boczek

    Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

  21. LCAP biomimetics - alicyclic amine derivatives as a new class of monoaminergic receptor ligands

    Call: OPUS 3 , Panel: NZ7

    Principal investigator: dr hab. Paweł Zajdel

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  22. Search for new "drug-like" molecules designed as adenosine receptors ligands

    Call: HARMONIA 2 , Panel: NZ4

    Principal investigator: prof. Katarzyna Kieć-Kononowicz

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  23. Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr hab. Danuta Dudzik

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  24. Study on novel sensing layers for determination of quorum sensing signal molecules

    Call: SONATA BIS 13 , Panel: ST5

    Principal investigator: dr hab. Kamila Sadowska

    Instytut Biocybernetyki i Inżynierii Biomedycznej im. Macieja Nałęcza Polskiej Akademii Nauk

  25. The role of free fatty acid receptors in pathophysiology of the functional gastrointestinal tract disorders: new therapi...

    Call: PRELUDIUM BIS 5 , Panel: NZ7

    Principal investigator: dr hab. Maciej Sałaga

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  26. Unraveling protease activation in stimulated CAR-T cells to identify new biomarkers for assessing their clinical efficac...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  27. Novel receptor materials for the construction of a bioelectronic nose for the rapid and efficient detection of lung canc...

    Call: OPUS 25 , Panel: ST5

    Principal investigator: prof. Wojciech Kamysz

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  28. Targeting the serotonin 5-HT7 receptor in a search for new strategies of mental disorders treatment

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Patryk Pyka

    Uniwersytet Jagielloński, Collegium Medicum

  29. EBI2 receptor as a new myelin repair therapy in multiple sclerosis.

    Call: SONATA 18 , Panel: NZ3

    Principal investigator: dr Aleksandra Rutkowska

    Gdański Uniwersytet Medyczny, Centrum Chorób Mózgu

  30. Studies on the post-receptor mechanisms of TSPO in search of a novel therapeutic target of metabolic syndrome

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Łukasz Kurach

    Uniwersytet Medyczny w Lublinie

  31. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Szczepańska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  32. Partial agonists of alpha-2 adrenoceptors as new perspective of the effective and safe in reducting body weight and obes...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr Magdalena Dudek

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  33. Soluble scavenger receptor cysteine-rich domain-containing protein - SSc5D, a new player of innate immunity in turkey (M...

    Call: OPUS 23 , Panel: NZ9

    Principal investigator: dr hab. Mariola Słowińska

    Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk

  34. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Przepiórska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  35. Novel tricyclic glycomimetics as DC-SIGN receptor ligands.

    Call: OPUS 22 , Panel: ST4

    Principal investigator: dr Mykhaylo Potopnyk

    Instytut Chemii Organicznej Polskiej Akademii Nauk

  36. Interleukin-18 receptor targeted gene therapy as a novel approach for the treatment of pulmonary hypertension using cont...

    Call: POLONEZ BIS 1 , Panel: NZ5

    Principal investigator: dr Tara Scott

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  37. Novel broad-spectrum central nervous system active substances: optimization of their multi-target profile

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Kaczor

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  38. Cinemagoing in German-occupied Poland: Cinema programming and film preferences of multi-ethnic urban audiences during Wo...

    Call: OPUS 22 , Panel: HS2

    Principal investigator: dr hab. Andrzej Dębski

    Uniwersytet Wrocławski, Centrum Studiów Niemieckich i Europejskich im. Willy Brandta

  39. Studies on anti-inflammatory properties of GPR18 ligands and their involvement in modulation of microglia phenotypes – a...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Katarzyna Kieć-Kononowicz

    Uniwersytet Jagielloński, Collegium Medicum

  40. New approach to the treatment of Alzheimer's disease targetingresolution of inflammation and modulation of biomechanical...

    Call: OPUS 22 , Panel: NZ4

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  41. New post-treatment strategy against stroke and perinatal asphyxia – a novel approach based on a selective activation of ...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Agnieszka Wnuk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  42. The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Kucwaj-Brysz

    Uniwersytet Jagielloński, Collegium Medicum

  43. Chronic pain in obesity: from cellular mechanisms to new strategies for targeted therapy.

    Call: SONATA 17 , Panel: NZ5

    Principal investigator: dr Anna Piotrowska-Murzyn

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  44. Novel combination therapies of pulmonary arterial hypertension targeting blockade of peripheral cannabinoid CB1 receptor...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Barbara Malinowska

    Uniwersytet Medyczny w Białymstoku

  45. Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Sylwia Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  46. Selective activation of non-nuclear Estrogen Receptor signaling with PaPE-1 as a novel therapeutic approach for sporadic...

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  47. The role of somatostatin- and parvalbumin interneurons in the modulation of neuronal function and synaptic plasticity vi...

    Call: OPUS 20 , Panel: NZ4

    Principal investigator: dr hab. Joanna Urban-Ciećko

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  48. A novel approach based on the optimized multidrug combination for glioblastoma treatment.

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Małgorzata Kucińska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  49. Identification and characterisation of novel anti-bacterial restriction factors

    Call: Polskie Powroty NAWA 2020 , Panel: NZ1

    Principal investigator: dr Michał Piotr Wandel

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  50. New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Przemysław Zaręba

    Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

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