Projects funded by the NCN

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53 projects found matching your search criteria :

  1. Flavonoid phytoprogestins as novel non-steroidal progesterone receptor modulators in a nutraceutical approach to endomet...

    Call: PRELUDIUM 24 , Panel: NZ9

    Principal investigator: Agata Gołąbek-Grenda

    Uniwersytet Przyrodniczy w Poznaniu

  2. Cholesin and its receptor as novel therapeutic and diagnostic targets in metabolic disorders

    Call: OPUS 29 , Panel: NZ7

    Principal investigator: prof. Wojciech Fendler

    Uniwersytet Medyczny w Łodzi

  3. Elimination of IgE-producing cells using next-generation chimeric antigen receptor (CAR)-based therapy

    Call: OPUS 29 , Panel: NZ6

    Principal investigator: dr hab. Beata Kaleta

    Warszawski Uniwersytet Medyczny

  4. New approach to glioblastoma adoptive therapy based on inducible CAR expression system - SynCAR

    Call: OPUS 29 , Panel: NZ6

    Principal investigator: dr hab. Radosław Zagożdżon

    Warszawski Uniwersytet Medyczny

  5. Positioning the aryl hydrocarbon receptor (AhR) as a new target for pharmacotherapy of sporadic Alzheimer disease: verif...

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii PAN

  6. Decoding the novel role of the histamine H3 receptor in opioid-induced analgesia and hyperalgesia: studies toward innova...

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: dr Katarzyna Popiołek-Barczyk

    Instytut Farmakologii PAN

  7. Adopted orphan nuclear receptors as new regulators of testis immune privilege

    Call: SONATA 20 , Panel: NZ3

    Principal investigator: dr Alicja Kinga Kamińska

    Uniwersytet Jagielloński

  8. Novel receptor materials for the construction of a bioelectronic nose for the rapid and efficient detection of lung canc...

    Call: OPUS 25 , Panel: ST5

    Principal investigator: prof. Wojciech Kamysz

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  9. EBI2 receptor as a new myelin repair therapy in multiple sclerosis.

    Call: SONATA 18 , Panel: NZ3

    Principal investigator: dr hab. Aleksandra Rutkowska

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  10. Studies on the post-receptor mechanisms of TSPO in search of a novel therapeutic target of metabolic syndrome

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: dr Łukasz Kurach

    Uniwersytet Medyczny w Lublinie

  11. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Anna Szczepańska

    Instytut Farmakologii PAN

  12. Soluble scavenger receptor cysteine-rich domain-containing protein - SSc5D, a new player of innate immunity in turkey (M...

    Call: OPUS 23 , Panel: NZ9

    Principal investigator: dr hab. Mariola Słowińska

    Instytut Rozrodu Zwierząt i Badań Żywności PAN

  13. Novel tricyclic glycomimetics as DC-SIGN receptor ligands.

    Call: OPUS 22 , Panel: ST4

    Principal investigator: dr Mykhaylo Potopnyk

    Instytut Chemii Organicznej Polska Akademia Nauk

  14. Novel broad-spectrum central nervous system active substances: optimization of their multi-target profile

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Anna Kaczor

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  15. Studies on anti-inflammatory properties of GPR18 ligands and their involvement in modulation of microglia phenotypes – a...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Dorota Justyna Łażewska

    Uniwersytet Jagielloński, Collegium Medicum

  16. New approach to the treatment of Alzheimer's disease targetingresolution of inflammation and modulation of biomechanical...

    Call: OPUS 22 , Panel: NZ4

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  17. The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Maria Kucwaj-Brysz

    Uniwersytet Jagielloński, Collegium Medicum

  18. Chronic pain in obesity: from cellular mechanisms to new strategies for targeted therapy.

    Call: SONATA 17 , Panel: NZ5

    Principal investigator: dr Anna Piotrowska-Murzyn

    Instytut Farmakologii PAN

  19. Novel combination therapies of pulmonary arterial hypertension targeting blockade of peripheral cannabinoid CB1 receptor...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Barbara Malinowska

    Uniwersytet Medyczny w Białymstoku

  20. Selective activation of non-nuclear Estrogen Receptor signaling with PaPE-1 as a novel therapeutic approach for sporadic...

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii PAN

  21. A novel approach based on the optimized multidrug combination for glioblastoma treatment.

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kucińska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  22. New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: dr Przemysław Patryk Zaręba

    Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

  23. New mechanisms regulating acetylcholine receptors at the neuromuscular junction

    Call: OPUS 19 , Panel: NZ3

    Principal investigator: dr hab. Tomasz Jacek Prószyński

    Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

  24. Recognition of expression and function of new neuropeptide - phoenixin-14 in porcine corpus luteum.

    Call: PRELUDIUM 19 , Panel: NZ9

    Principal investigator: Ewa Maria Mlyczyńska

    Uniwersytet Jagielloński, Wydział Biologii

  25. Dual histamine H3 and sigma-1 receptor ligands as novel pharmacological tools in the treatment of central nervous system...

    Call: SONATINA 4 , Panel: NZ7

    Principal investigator: dr Katarzyna Anna Szczepańska

    Instytut Farmakologii PAN

  26. Neuroprotective properties of 5-HT6 receptor ligands in the group of 2-arylpyrrole derivatives – a new insight into neur...

    Call: PRELUDIUM 17 , Panel: NZ7

    Principal investigator: Marcin Józef Drop

    Uniwersytet Jagielloński, Collegium Medicum

  27. Effects of a novel nonaddictive opioid on response to stress

    Call: PRELUDIUM 17 , Panel: NZ7

    Principal investigator: dr Łucja Elżbieta Szumiec

    Instytut Farmakologii PAN

  28. New calcitriol analogues with unnatural D ring

    Call: PRELUDIUM 16 , Panel: ST5

    Principal investigator: Adrian Fabisiak

    Uniwersytet Warszawski, Wydział Chemii

  29. Novel hybrid 5-HT6 serotonin receptor and SERT transporter ligands as a therapeutic perspective of behavioural and cogni...

    Call: SONATA 14 , Panel: NZ7

    Principal investigator: dr Agata Siwek

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  30. Characterization of genetic determinants of the mannose-specific phosphotransferase system (Man-PTS) determining sensiti...

    Call: PRELUDIUM 15 , Panel: NZ1

    Principal investigator: dr Aleksandra Tymoszewska

    Instytut Biochemii i Biofizyki PAN

  31. New strategies in neuropathic pain pharmacotherapy based on the modulation of the functions of chemokine receptors CCR2 ...

    Call: PRELUDIUM 15 , Panel: NZ7

    Principal investigator: dr Klaudia Kwiatkowski

    Instytut Farmakologii PAN

  32. New derivatives of clopidogrel - enantioselective biosynthesis and antiplatelet activity in vitro

    Call: PRELUDIUM 14 , Panel: NZ7

    Principal investigator: Adam Edward Sikora

    Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy; Wydział Farmaceutyczny

  33. Novel multi-target ligands of aminergic GPCRs as pharmacological tools to study the pathomechanism of schzophrenia

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Anna Kaczor

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  34. STIM proteins as new regulators of NMDA receptor trafficking in neurons

    Call: SONATA BIS 7 , Panel: NZ3

    Principal investigator: dr Joanna Edyta Gruszczyńska-Biegała

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  35. New receptors for C-reactive protein recognition - generation, characterization and application towards fast differentia...

    Call: SONATA 13 , Panel: ST5

    Principal investigator: dr Katarzyna Szot-Karpińska

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  36. Novel ligands of histamine receptor H4 as potential anti-allergic and anti-inflammatory drugs

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Sławomir Hubert Filipek

    Uniwersytet Warszawski, Wydział Chemii

  37. Evaluation of the anticancer efficacy of a new chimeric antigen receptor targeting PD-L1 molecule

    Call: OPUS 12 , Panel: NZ6

    Principal investigator: dr hab. Radosław Zagożdżon

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  38. Evaluation of relationship between markers of Epstein-Barr virus infection and selected immune parameters in patients wi...

    Call: OPUS 12 , Panel: NZ6

    Principal investigator: prof. Wojciech Tomasz Załuska

    Uniwersytet Medyczny w Lublinie, Wydział Lekarski

  39. New mulitple target-directed ligands - A1/A2A adenosine receptors antagonists and monoamine oxidase B inhibitors - searc...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Michał Karol Załuski

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  40. Novel multi-target directed ligands combining cholinesterase inhibition and 5-HT6 antagonism - design, synthesis and pha...

    Call: SONATA 12 , Panel: NZ7

    Principal investigator: dr hab. Anna Karolina Więckowska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  41. Maternal diet during gestation and nutrition as a risk factor for cocaine use disorder in offspring - preclinical behavi...

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: prof. Małgorzata Maria Filip

    Instytut Farmakologii PAN

  42. Simultaneous stimulation of muscarinic M4 receptor and selected receptors involved in the regulation of glutamate releas...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: dr hab. Joanna Monika Wierońska

    Instytut Farmakologii PAN

  43. New selective antagonists of ionotropic glutamate non-NMDA receptors

    Call: OPUS 8 , Panel: NZ7

    Principal investigator: dr Ewa Monika Szymańska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  44. The new homology model of H3 histaminic receptor - structure, interaction with ligand

    Call: PRELUDIUM 8 , Panel: NZ7

    Principal investigator: Jakub Józef Jończyk

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  45. Novel polyelectrolytes as potential inhibitors of HSV-1 virus - synthesis, properties and mechanism of action

    Call: OPUS 7 , Panel: ST5

    Principal investigator: prof. Maria Nowakowska

    Uniwersytet Jagielloński, Wydział Chemii

  46. Stearoyl-CoA desaturase and intracellular lipid signaling as novel players in regulation of thyroid hormone action in th...

    Call: OPUS 7 , Panel: NZ4

    Principal investigator: dr hab. Paweł Dobrzyń

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  47. Novel type modulators of purinergic receptors - Synthesis and study of receptor-ligand interaction

    Call: OPUS 7 , Panel: NZ1

    Principal investigator: prof. Zbigniew Jan Leśnikowski

    Instytut Biologii Medycznej PAN

  48. Analysis of the structural and functional mechanisms of action of the nicotinic receptors modulators.

    Call: SONATA 5 , Panel: NZ7

    Principal investigator: dr Katarzyna Małgorzata Targowska-Duda

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

  49. Novel C3 symmetric triptycene derivatives useful for construction of artificial anion receptors

    Call: PRELUDIUM 4 , Panel: ST5

    Principal investigator: dr Jarosław Marek Granda

    Instytut Chemii Organicznej Polska Akademia Nauk

  50. PHARMACOTHERAPY OF OSTEOARTHRITIS: TRPV1 AND CB1 RECEPTORS AND THEIR ENDOGENOUS LIGANDS AS NEW TARGETS FOR PHARMACOLOGIC...

    Call: SONATA BIS 2 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Maria Starowicz-Bubak

    Instytut Farmakologii PAN

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