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STIM proteins as new regulators of NMDA receptor trafficking in neurons

2017/26/E/NZ3/01144

Keywords:

STIM NMDA receptor trafficking neurons

Descriptors:

  • NZ3_6: Cell neurobiology
  • NZ3_7: Signal transduction
  • NZ3_5: Molecular neurobiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Joanna Gruszczyńska-Biegała 

Number of co-investigators in the project: 4

Call: SONATA BIS 7 - announced on 2017-06-14

Amount awarded: 1 999 191 PLN

Project start date (Y-m-d): 2018-08-01

Project end date (Y-m-d): 2024-01-31

Project duration:: 60 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (2)
  1. STIM protein-NMDA2 receptor interaction decreases NMDA-dependent calcium levels in cortical neurons
    Authors:
    Gruszczynska-Biegala Joanna*, Strucinska Klaudia, Maciag Filip, Majewski Lukasz, Sladowska Maria, Kuznicki Jacek
    Academic press:
    Cells (rok: 2020, tom: 9(1)160, strony: 45680), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells9010160 - link to the publication
  2. Target Molecules of STIM Proteins in the Central Nervous System
    Authors:
    Karolina Serwach and Joanna Gruszczynska-Biegala *
    Academic press:
    Frontiers in Molecular Neuroscience (rok: 2020, tom: 13:617422, strony: 45680), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fnmol.2020.617422 - link to the publication
  3. STIM Proteins and Glutamate Receptors in Neurons: Role in Neuronal Physiology and Neurodegenerative Diseases
    Authors:
    Karolina Serwach and Joanna Gruszczynska-Biegala *
    Academic press:
    Int. J. Mol. Sci. (rok: 2019, tom: 20(9), 2289, strony: 45706), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20092289 - link to the publication
  4. STIM2 regulates NMDA receptor endocytosis that is induced by short-term NMDA receptor overactivation in cortical neurons
    Authors:
    Karolina Serwach, Ewa Nurowska, Marta Klukowska, Barbara Zablocka, Joanna Gruszczynska-Biegala*
    Academic press:
    Cellular and Molecular Life Sciences (rok: 2023, tom: 80, strony: 45680), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1007/s00018-023-05028-8 - link to the publication
  1. STIM2 regulates NMDAR endocytosis after its overactivation
    Authors:
    Karolina Serwach, Barbara Zabłocka, Joanna Gruszczynska-Biegala*
    Conference:
    12th Neuronus 2022 Neuroscience Forum (rok: 2022, ), Wydawca: Nencki Institute of Experimental Biology Polish Academy of Sciences
    Data:
    konferencja 15-17.10.2022
    Status:
    Published
  2. Study of the influence of STIM proteins on NMDA receptor trafficking in dissociated rat cortical neurons.
    Authors:
    Martyna Baczek, Karolina Serwach, Barbara Zablocka, Joanna Gruszczynska-Biegala*
    Conference:
    The XVth International Symposium Molecular Basis of Pathology and Therapy in Neurological Disorders (rok: 2022, ), Wydawca: Mossakowski Medical Research Institute Polish Academy of Sciences
    Data:
    konferencja 20-22.10.2022
    Status:
    Published

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