Projects funded by the NCN
Neuroprotective properties of 5-HT6 receptor ligands in the group of 2-arylpyrrole derivatives – a new insight into neurodegenerative diseases treatment strategy.
2019/33/N/NZ7/01875
Keywords:
Neuroprotection 5-HT6 receptor constitutive activity neutral antagonist 2-arylpyrrole neurodegenerative disorders
Descriptors:
- NZ7_014:
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Uniwersytet Jagielloński, Collegium Medicum
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 3
Call: PRELUDIUM 17 - announced on 2019-03-15
Amount awarded: 139 700 PLN
Project start date (Y-m-d): 2020-02-17
Project end date (Y-m-d): 2023-02-16
Project duration:: 36 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- 5-HT6 receptor neutral antagonists protect astrocytes: A lesson from 2-phenylpyrrole derivatives.Authors:Drop M, Koczurkiewicz-Adamczyk P, Bento O, Pietruś W, Satała G, Blicharz-Futera K, Canale V, Grychowska K, Bantreil X, Pękala E, Kurczab R, Bojarski AJ, Chaumont-Dubel S, Marin P, Lamaty F, Zajdel P.Academic press:European Journal of Medicinal Chemistry (rok: 2024, tom: 275, strony: 116615), Wydawca: Elsevier Masson SASStatus:PublishedDOI:10.1016/j.ejmech.2024.116615 - link to the publication