Projects funded by the NCN

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159 projects found matching your search criteria :

  1. Determination of the mechanisms responsible for the mobility of non-integrin laminin receptor (LamR) isoforms, including...

    Call: PRELUDIUM 19 , Panel: NZ1

    Principal investigator: Ewa Mazurkiewicz

    Uniwersytet Wrocławski, Wydział Biotechnologii

  2. Role of the Intersubunit and Interdomain Interactions in the GABAA Receptor Modulation by Protons.

    Call: ETIUDA 8 , Panel: NZ1

    Principal investigator: Michał Adam Michałowski

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  3. Chasing the HARE: elucidation of the binding mechanism of the new and unexplored ligandsof the Hyaluronic Acid Receptor ...

    Call: SONATINA 4 , Panel: NZ1

    Principal investigator: dr Aleksandra Anna Twarda-Cłapa

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  4. Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii PAN

  5. Seeking for CB1 and CB2 receptor ligands among drugs, drug metabolites, and phytochemical compounds

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Adam Stasiulewicz

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  6. Molecular mechanisms of interplay between RORγ/RORγT receptors and cyclin-dependent kinase inhibitor (AT7519). Analysis ...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Kaja Urszula Karaś

    Instytut Biologii Medycznej PAN

  7. Novel approach to the chiral recognition of organic cations and anions - dynamic combinatorial chemistry

    Call: MAESTRO 1 , Panel: ST5

    Principal investigator: prof. Janusz Jurczak

    Instytut Chemii Organicznej Polska Akademia Nauk

  8. Cytotoxic conjugates targeting FGFR-related cancers based on FGF1 and FGFR-specific antibodies.

    Call: MAESTRO 1 , Panel: NZ1

    Principal investigator: prof. Jacek Józef Otlewski

    Uniwersytet Wrocławski, Wydział Biotechnologii

  9. Co-crystallization and co-amorphization of angiotensin II receptor blockers leading to more soluble compounds with a bif...

    Call: PRELUDIUM 17 , Panel: ST5

    Principal investigator: dr Marika Ewa Turek

    Akademia im. Jana Długosza w Częstochowie

  10. Studies of the molecular mechanisms associated with HPV and CMV infections involved in the pathogenesis of ovarian cance...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: dr hab. Edyta Teresa Paradowska

    Instytut Biologii Medycznej PAN

  11. Specific interactions of new antitumor unsymmetrical bisacridines, UAs, with DNA and ABC proteins and their potential to...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: prof. Zofia Mazerska

    Politechnika Gdańska

  12. Dynamic combinatorial chemistry in the search for selective anion receptors

    Call: PRELUDIUM 1 , Panel: ST5

    Principal investigator: dr Filip Michał Ulatowski

    Instytut Chemii Organicznej Polska Akademia Nauk

  13. New calcitriol analogues with unnatural D ring

    Call: PRELUDIUM 16 , Panel: ST5

    Principal investigator: Adrian Fabisiak

    Uniwersytet Warszawski, Wydział Chemii

  14. Chemical synthesis of 1-O-acyl-2-O-methyl-3-O-phosphodiester and 1-O-acyl-2-O-methyl-3-O-phosphorothioate analogs of sel...

    Call: OPUS 1 , Panel: ST5

    Principal investigator: prof. Andrzej Okruszek

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  15. Epigenomic, immunogenetic and proteomic strategies for identification of NK cell determinants of prognostic value for pa...

    Call: OPUS 16 , Panel: NZ2

    Principal investigator: prof. Katarzyna Maria Bogunia-Kubik

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  16. Development of a comprehensive set of computational tools for the search of new ligands of particular receptor - case st...

    Call: OPUS 16 , Panel: NZ2

    Principal investigator: dr hab. Sabina Marta Podlewska

    Instytut Farmakologii PAN

  17. Searching for mu opioid receptor peptide agonists with G protein/beta-arrestin biased profile and their pharmacological ...

    Call: SONATA 14 , Panel: ST5

    Principal investigator: dr Justyna Piekielna-Ciesielska

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  18. Recognition, transport and extraction of salts via modular molecular receptors

    Call: SONATA BIS 8 , Panel: ST5

    Principal investigator: dr hab. Jan Romański

    Uniwersytet Warszawski, Wydział Chemii

  19. Extension of the CABS-dock method for protein-peptide docking to modelling of membrane proteins

    Call: PRELUDIUM 15 , Panel: NZ1

    Principal investigator: Maciej Paweł Ciemny

    Uniwersytet Warszawski, Wydział Chemii

  20. Molecular characterisation of novel mutations in the gene encoding the luteinizing hormone/choriogonadotropin receptor (...

    Call: PRELUDIUM 15 , Panel: NZ5

    Principal investigator: dr Kamila Julita Adamczuk

    Uniwersytet Medyczny w Lublinie

  21. Molecular Mechanisms of GABAA Receptor Allosteric Modulation by pH Level.

    Call: PRELUDIUM 15 , Panel: NZ1

    Principal investigator: Michał Adam Michałowski

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  22. Characterization of genetic determinants of the mannose-specific phosphotransferase system (Man-PTS) determining sensiti...

    Call: PRELUDIUM 15 , Panel: NZ1

    Principal investigator: dr Aleksandra Tymoszewska

    Instytut Biochemii i Biofizyki PAN

  23. MOLECULAR DETERMINANTS OF SIGNAL PROPAGATION IN THE DELTA AND MU OPIOID RECEPTORS - IN SEARCH FOR ANALGETICS WITH LESS S...

    Call: PRELUDIUM 14 , Panel: NZ2

    Principal investigator: Tomasz Maciej Stepniewski

    Uniwersytet Warszawski, Wydział Chemii

  24. Polymorphisms in otolin-1 genes in human and zebrafish - influence on function of the C1q-like domain in biomineralizati...

    Call: PRELUDIUM 14 , Panel: NZ1

    Principal investigator: dr Rafał Hołubowicz

    Politechnika Wrocławska

  25. Novel multi-target ligands of aminergic GPCRs as pharmacological tools to study the pathomechanism of schzophrenia

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Anna Kaczor

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  26. Molecular mechanism of anticancer action of selected NSAIDs as a PPAR gamma receptor agonists in experimental models of ...

    Call: PRELUDIUM 14 , Panel: NZ7

    Principal investigator: Adam Kazberuk

    Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  27. Structural and functional analysis of the C-terminal region of Germ cell-expressed protein (GceC) from Drosophila melano...

    Call: PRELUDIUM 14 , Panel: NZ1

    Principal investigator: dr Marta Katarzyna Kolonko-Adamska

    Politechnika Wrocławska

  28. New receptors for C-reactive protein recognition - generation, characterization and application towards fast differentia...

    Call: SONATA 13 , Panel: ST5

    Principal investigator: dr Katarzyna Szot-Karpińska

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  29. Small-molecule inhibitors for characterization of the interaction between extracellular domains of Programmed Cell Death...

    Call: MAESTRO 9 , Panel: ST5

    Principal investigator: prof. Tadeusz Andrzej Holak

    Uniwersytet Jagielloński, Wydział Chemii

  30. Neutral homo- and heteronuclear bismacrocyclic metal complexes as components of interlocked molecules.

    Call: PRELUDIUM 1 , Panel: ST5

    Principal investigator: Iwona Mames

    Instytut Chemii Organicznej Polska Akademia Nauk

  31. Multiscale investigations on polymorphism of the beta2-adrenergic receptor: from molecular-scale processes to heart fail...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Anita Płazińska

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  32. Development of unique molecular probes: low-basicity agonists for the study of 5-HT7 receptor function

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Andrzej Jacek Bojarski

    Instytut Farmakologii PAN

  33. Designing and application of synthetic receptors for protein hormones

    Call: OPUS 13 , Panel: ST4

    Principal investigator: dr hab. Piyush Sindhu Sharma

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  34. Evaluation of the anticancer efficacy of a new chimeric antigen receptor targeting PD-L1 molecule

    Call: OPUS 12 , Panel: NZ6

    Principal investigator: dr hab. Radosław Zagożdżon

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  35. Molecular modeling of allosteric binding and allosteric-orthosteric coupling in cannabinoid receptor CB1

    Call: PRELUDIUM 12 , Panel: NZ1

    Principal investigator: Jakub Jakub Jakowiecki

    Uniwersytet Warszawski, Wydział Chemii

  36. Development of novel light-controllable azobenzene switches as molecular receptors for selective sensing and transport o...

    Call: SONATA 12 , Panel: ST5

    Principal investigator: dr Kajetan Jerzy Dąbrowa

    Instytut Chemii Organicznej Polska Akademia Nauk

  37. The effect of membrane domains on the G protein-lipid interactions

    Call: OPUS 12 , Panel: NZ1

    Principal investigator: dr Agnieszka Polit

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  38. Characteristic of plant extracts inhibit the binding of Shiga toxin to Gb3 receptors.

    Call: PRELUDIUM 12 , Panel: NZ1

    Principal investigator: Magdalena Komiażyk-Mikulska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  39. Molecular identification of signalling pathways activated by receptor kinase CRK5 during senescence and stress response ...

    Call: SONATA 12 , Panel: NZ1

    Principal investigator: dr Paweł Burdiak

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

  40. Piperazine derivatives as active histamine H3 receptor ligands - molecular modeling, synthesis, pharmacological evaluati...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Katarzyna Anna Szczepańska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  41. Study of the hormonal and molecular mechanisms of tumorigenesis in the interstitial tissue of the male gonad

    Call: OPUS 12 , Panel: NZ4

    Principal investigator: prof. Barbara Bilińska

    Uniwersytet Jagielloński, Wydział Biologii

  42. Impact of palmitoylation on the Zn(II)-dependent interaction between CD4 coreceptor and Lck tyrosine kinase.

    Call: PRELUDIUM 11 , Panel: NZ1

    Principal investigator: Anna Marta Kocyła

    Uniwersytet Wrocławski, Wydział Biotechnologii

  43. Molecular receptors as a tool for studies of interactions agonist/antagonist of H1 - H4 receptors

    Call: PRELUDIUM 11 , Panel: ST5

    Principal investigator: Małgorzata Ewa Walczak

    Politechnika Łódzka, Wydział Chemiczny

  44. Structural studies of signaling receptors HVEM/CD160 as potential targets for immunoterapy against melanoma

    Call: SONATA 11 , Panel: NZ1

    Principal investigator: dr Marta Orlikowska

    Uniwersytet Gdański, Wydział Chemii

  45. Molecular propellers, bevel gears and sea anemones - dynamically chiral triarylmethyl derivatives as versatile stereoche...

    Call: OPUS 11 , Panel: ST5

    Principal investigator: dr hab. Marcin Grzegorz Kwit

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  46. Comparison of adhesive properties and traction forces in bladder cancer cells of various malignancies cultured on polyme...

    Call: PRELUDIUM 11 , Panel: NZ1

    Principal investigator: Joanna Krystyna Danilkiewicz

    Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego PAN

  47. Pochodne azulenu jako bloki budulcowe w konstrukcji selektywnych receptorów anionów

    Call: ETIUDA 4 , Panel: ST5

    Principal investigator: Dawid Grzegorz Lichosyt

    Instytut Chemii Organicznej Polska Akademia Nauk

  48. Molecular and functional analysis of interleukin 18 (IL-18) its receptor (IL-18R) and IL-18- binding protein (IL-18BP) i...

    Call: PRELUDIUM 10 , Panel: NZ6

    Principal investigator: Sebastian Wawrocki

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  49. The role of the neuron-microglia CX3CL1-CX3CR1 and CD200-CD200R protein systems in molecular mechanisms of antipsychotic...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  50. Molecular mechanism of interactions between GPCRs and G protein.

    Call: PRELUDIUM 10 , Panel: NZ2

    Principal investigator: Stefan Mateusz Mordalski

    Instytut Farmakologii PAN

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