Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Molecular mechanism underlying the anti-inflammatory action of CB2 receptor agonists in microglia: participation of the proteases of the NLRP3 inflammasome pathway.

2020/37/B/NZ7/03411

Keywords:

neuroinflammation microglia CB2 receptor CB2 receptor agonists pyroptosis NFkB pathway NLRP3 inflammasome caspase 1 caspase 11 caspase 4 cathepsin B

Descriptors:

  • NZ3_5: Molecular neurobiology
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ5_7: Human disease treatment

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Politechnika Wrocławska

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Natalia Małek-Chudzik 

Number of co-investigators in the project: 1

Call: OPUS 19 - announced on 2020-03-16

Amount awarded: 696 000 PLN

Project start date (Y-m-d): 2021-02-01

Project end date (Y-m-d): 2023-01-31

Project duration:: 24 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.