Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Investigation into the mechanism of regulation of nicotinic acetylcholine receptors

2020/37/K/NZ3/04098

Keywords:

nAChR AChBP pLGIC nicotinic acetylcholine receptor acetylcholine binding protein pentameric ligand-gated ion channel VHH nanobody regulation intracellular domain

Descriptors:

  • NZ3_5: Molecular neurobiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Nauk Biologicznych i Weterynaryjnych

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Ákos Nemecz 

Number of co-investigators in the project: 3

Call: POLS - announced on 2020-03-16

Amount awarded: 937 640 PLN

Project start date (Y-m-d): 2021-04-01

Project end date (Y-m-d): 2023-10-31

Project duration:: 31 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. The versatility of VHH nanobodies against pentameric ligand-gated ion channels
    Authors:
    Dorota Nemecz, Weronika A. Nowak, Ákos Nemecz
    Academic press:
    Journal of Medicinal Chemistry (rok: 2024, tom: 67(11), strony: 8502-8518), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acs.jmedchem.4c00231 - link to the publication