Projects funded by the NCN

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247 projects found matching your search criteria :

  1. Impact of subcellular localization on the specificity of selected enzymes involved in the biosynthesis and metabolism of...

    Call: OPUS 16 , Panel: NZ3

    Principal investigator: dr hab. Paweł Bednarek

    Instytut Chemii Bioorganicznej PAN

  2. Structural and functional characterization of loci determining the content of cell wall-bound phenolics under the condit...

    Call: OPUS 16 , Panel: NZ9

    Principal investigator: dr hab. Tomasz Hura

    Instytut Fizjologii Roślin im. Franciszka Górskiego PAN

  3. Synthesis and characterization of new molecular probes for monitoring activity of enzymes associated with RNA decapping ...

    Call: OPUS 16 , Panel: ST5

    Principal investigator: dr hab. Joanna Kowalska

    Uniwersytet Warszawski, Wydział Fizyki

  4. Inhibition of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa by targeting the enzyme dynamics

    Call: SONATA BIS 8 , Panel: NZ1

    Principal investigator: dr hab. Krzysztof Brzeziński

    Instytut Chemii Bioorganicznej PAN

  5. Application of lanthanides in activity-based probes for the simultaneous detection of proteolytic enzymes.

    Call: HARMONIA 10 , Panel: ST5

    Principal investigator: prof. Marcin Drąg

    Politechnika Wrocławska, Wydział Chemiczny

  6. Stomach microbiome in Helicobacter pyliri-infected patients

    Call: OPUS 15 , Panel: NZ6

    Principal investigator: dr hab. Krystyna Dąbrowska

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  7. CP protease of the O'nyong-nyong virus: substrate profiling, design and synthesis of inhibitors and activity-based probe...

    Call: OPUS 15 , Panel: NZ6

    Principal investigator: dr hab. Marcin Sieńczyk

    Politechnika Wrocławska

  8. Dissecting the mechanisms of proteolytic cross-talk underlying pyroptosis, a programmed inflammatory cell death.

    Call: OPUS 15 , Panel: NZ1

    Principal investigator: dr Marcin Łukasz Poręba

    Politechnika Wrocławska

  9. Factors determining changes in enzymatic activity as well as the functional and genetic diveristy of microorganisms acro...

    Call: OPUS 15 , Panel: NZ9

    Principal investigator: prof. Anna Halina Piotrowska-Długosz

    Uniwersytet Technologiczno-Przyrodniczy im. Jana i Jędrzeja Śniadeckich w Bydgoszczy, Wydział Rolnictwa i Biotechnologii

  10. Amphiphilic copolymers containing polystyrene and polyglycidol blocks with varied architecture and their functionalized ...

    Call: OPUS 15 , Panel: ST4

    Principal investigator: dr hab. Stanisław Kazimierz Słomkowski

    Centrum Badań Molekularnych i Makromolekularnych PAN

  11. Novel biocatalytic systems obtained after enzymes immobilization onto multifunctional materials synthesized via electros...

    Call: PRELUDIUM 15 , Panel: ST8

    Principal investigator: Katarzyna Anna Jankowska

    Politechnika Poznańska, Wydział Technologii Chemicznej

  12. The role of diacylglycerol kinase epsilon, an enzyme of the phosphatidylinositol cycle, in the regulation of LPS-induced...

    Call: OPUS 15 , Panel: NZ3

    Principal investigator: prof. Katarzyna Kwiatkowska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  13. New derivatives of clopidogrel - enantioselective biosynthesis and antiplatelet activity in vitro

    Call: PRELUDIUM 14 , Panel: NZ7

    Principal investigator: Adam Edward Sikora

    Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy; Wydział Farmaceutyczny

  14. Adaptation of electrophoretic methods for the determination of the impact of food components on global DNA methylation.

    Call: PRELUDIUM 14 , Panel: NZ9

    Principal investigator: Monika Baranowska

    Politechnika Gdańska, Wydział Chemiczny

  15. The study of chitinolytic enzymes, aiming at constructing an artificial chitinosome.

    Call: OPUS 14 , Panel: NZ1

    Principal investigator: prof. Wojciech Robert Rypniewski

    Instytut Chemii Bioorganicznej PAN

  16. Tungstene-containing aldehyde oxidoreductase from Aromatoleum aromaticum - study of catalytic reaction mechanism

    Call: PRELUDIUM 14 , Panel: ST4

    Principal investigator: Agnieszka Winiarska

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  17. The study of the physiology of yeast Yarrowia lipolytica for decomposing of plastic.

    Call: OPUS 14 , Panel: NZ9

    Principal investigator: dr hab. Aleksandra Maria Mirończuk

    Uniwersytet Przyrodniczy we Wrocławiu, Wydział Biotechnologii i Nauk o Żywności

  18. Advanced MxOy/biopolymer hybrid platforms for enzymatic biosensors: Design, characteristic and application

    Call: OPUS 14 , Panel: ST8

    Principal investigator: prof. Teofil Jesionowski

    Politechnika Poznańska, Wydział Technologii Chemicznej

  19. Comprehensive research on enzymatic hydrolysis of native and chemically modified 5' RNA structures by Nudix protein fami...

    Call: OPUS 14 , Panel: NZ1

    Principal investigator: prof. Edward Darżynkiewicz

    Uniwersytet Warszawski, Wydział Fizyki

  20. New biocatalytic systems: carbon nanomaterial - enzyme, with controlled activity and potential application in anticancer...

    Call: PRELUDIUM 14 , Panel: ST5

    Principal investigator: Paulina Erwardt

    Uniwersytet Mikołaja Kopernika, Wydział Chemii

  21. Effects of pesticides on the red mason bee Osmia bicornis in agricultural landscapes: mixture toxicity and the evolution...

    Call: SONATA 13 , Panel: NZ8

    Principal investigator: dr Agnieszka Bednarska

    Instytut Ochrony Przyrody PAN

  22. Molecular origins of mechanisms governing biological functions of enzymes with buried actives sites: substrate inhibitio...

    Call: SONATA BIS 7 , Panel: NZ1

    Principal investigator: dr Jan Brezovsky

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  23. Aminophosphonates bearing fluorine atoms as inhibitors odf aminopeptideses and their potential application for determina...

    Call: HARMONIA 9 , Panel: ST5

    Principal investigator: prof. Paweł Kazimierz Kafarski

    Politechnika Wrocławska

  24. Dual-function tail phage proteins- determination of the function and the mechanism of action towards (poly)saccharides

    Call: SONATA BIS 7 , Panel: NZ1

    Principal investigator: dr Ewa Brzozowska

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  25. Structure and function of anti-virulent phage origin enzymes active against ESKAPE pathogens

    Call: HARMONIA 9 , Panel: NZ1

    Principal investigator: prof. Zuzanna Drulis-Kawa

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  26. The enzymes of RNA metabolism, PAP I and PNPase, as targets for new antimycobacterial drugs and their functional charact...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Jarosław Dziadek

    Instytut Biologii Medycznej PAN

  27. Biomedical materials modification by proteolytic enzymes inhibitors

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Anna Beata Jarosz-Wilkołazka

    Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

  28. Functions of Fusarium-produced lytic enzymes and mycotoxins in pathogenesis and of metabolites responsible for plant def...

    Call: OPUS 13 , Panel: NZ9

    Principal investigator: prof. Łukasz Wojciech Stępień

    Instytut Genetyki Roślin PAN

  29. The role of reactive oxygen species (ROS) generated during a maximal exercise by endothelial NOX2 i NOX4 in the regulati...

    Call: PRELUDIUM 13 , Panel: NZ4

    Principal investigator: dr Kamil Przyborowski

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  30. Changes at different levels of body organization in adult specimens of Lithobius forficatus exposed to continuous cadmiu...

    Call: OPUS 13 , Panel: NZ4

    Principal investigator: prof. Magdalena Maria Rost-Roszkowska

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

  31. Analysis of molecular mechanisms of frost tolerance in Lolium multiflorum/Festuca arundinacea introgression forms

    Call: PRELUDIUM 13 , Panel: NZ9

    Principal investigator: Adam Jan Augustyniak

    Instytut Genetyki Roślin PAN

  32. The effect of lead on the generation of signal molecules and their impact on the regulation of flavonoid biosynthesis in...

    Call: PRELUDIUM 13 , Panel: NZ9

    Principal investigator: dr Agnieszka Maria Woźniak

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i Bioinżynierii

  33. The effect of molecular structure of starch depolymerisation products, obtained by controlled microwave heating, on thei...

    Call: PRELUDIUM 13 , Panel: NZ9

    Principal investigator: dr Kamila Anna Kapuśniak

    Akademia im. Jana Długosza w Częstochowie, Wydział Matematyczno-Przyrodniczy

  34. Structural studies on inhibition mechanisms of enzymes belonging to USP family, which remove ubiquitin from eukaryotic p...

    Call: SONATINA 1 , Panel: NZ1

    Principal investigator: dr Marcin Jarosław Ziemniak

    Uniwersytet Warszawski, Wydział Chemii

  35. Promutagenic function of ubiquitin enzyme variant Mms2 in S. cerevisiae cells.

    Call: PRELUDIUM 12 , Panel: NZ3

    Principal investigator: Michał Roman Krawczyk

    Instytut Biochemii i Biofizyki PAN

  36. Synthesis of 2-phosphonocarboxylates as potential covalent inhibitors of Rab geranylgeranyl transferase

    Call: PRELUDIUM 12 , Panel: ST5

    Principal investigator: Joanna Natalia Małolepsza

    Politechnika Łódzka, Wydział Chemiczny

  37. New examples of enzyme catalytic promiscuity. Enzyme-catalyzed transformations of imines: stereoselective nitroalkane ad...

    Call: OPUS 12 , Panel: ST5

    Principal investigator: prof. Piotr Jan Kiełbasiński

    Centrum Badań Molekularnych i Makromolekularnych PAN

  38. Solid phase microextraction-based universal analytical platform for assessment of in vitro generated metabolism

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Karol Paweł Jaroch

    Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy; Wydział Farmaceutyczny

  39. Cytoplasmic enzymes of pathogenic fungi Candida spp. that moonlight as adhesins on the cell wall - structural determinan...

    Call: OPUS 12 , Panel: NZ6

    Principal investigator: prof. Andrzej Kozik

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  40. The role of tyrosine phosphorylation in posttranslational processing and secretion of major virulence factors of Porphyr...

    Call: PRELUDIUM 12 , Panel: NZ1

    Principal investigator: dr Zuzanna Maria Nowakowska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  41. Nanocrystalline oxide semiconductors obtained with the use of enzymes

    Call: SONATA 12 , Panel: ST8

    Principal investigator: dr Piotr Wieciński

    Politechnika Warszawska, Wydział Chemiczny

  42. Investigating the role of human tissue kallikreins in regulating matrix metalloproteinase activity.

    Call: PRELUDIUM 12 , Panel: NZ1

    Principal investigator: Katherine Monique Falkowski

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  43. Differences in chitinolytic enzyme system of Bacillus cereus sensu lato as result of adaptation to ecologically distinct...

    Call: SONATA 12 , Panel: NZ8

    Principal investigator: dr Justyna Małgorzata Drewnowska

    Uniwersytet w Białymstoku, Wydział Biologiczno-Chemiczny

  44. Resolving structure and functions of RECQL4 and BLM helicases to understand consequences of deleterious genetic alterati...

    Call: HARMONIA 8 , Panel: NZ3

    Principal investigator: prof. Bożena Kamińska-Kaczmarek

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  45. Molecular and bioinformatic analysis of interactions between dioxins different in their toxixity (DiCDD,TCDD) and enzyme...

    Call: PRELUDIUM 11 , Panel: NZ9

    Principal investigator: Tomasz Molcan

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

  46. Application of ene-reductases in enzymatic, stereoselective synthesis of heteroorganic compounds

    Call: PRELUDIUM 11 , Panel: ST5

    Principal investigator: Ignacy Przemysław Janicki

    Centrum Badań Molekularnych i Makromolekularnych PAN

  47. The mechanism of regioselective oxidative dehydrogenation of 3-ketosteroids catalyzed by D1-cholest-4-en-3-one dehydroge...

    Call: OPUS 11 , Panel: ST4

    Principal investigator: prof. Maciej Szaleniec

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  48. Soil biochemical properties and stabilization soil organic matter in relation to deadwood of different tree species

    Call: SONATA 11 , Panel: NZ9

    Principal investigator: dr hab. Ewa Błońska

    Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Leśny

  49. Mechanism of interaction between carbon nanoparticles of diamond, graphene oxide and graphite and cytochrome P450 enzyme...

    Call: PRELUDIUM 11 , Panel: NZ7

    Principal investigator: Barbara Agnieszka Strojny

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Wydział Nauk o Zwierzętach

  50. The influence of simultaneous inhibition of endocannabinoid degrading enzymes FAAH and MAGL by JZL195 on the cardiovascu...

    Call: PRELUDIUM 11 , Panel: NZ7

    Principal investigator: Marek Toczek

    Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

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