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Information on the principal investigator and host institution

Information of the project and the call

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Application of lanthanides in activity-based probes for the simultaneous detection of proteolytic enzymes.

2018/30/M/ST5/00440

Keywords:

protease activity-based probe imaging

Descriptors:

  • ST5_16:
  • ST5_23:
  • NZ1_2: Biochemistry

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Politechnika Wrocławska

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Marcin Drąg 

Number of co-investigators in the project: 4

Call: HARMONIA 10 - announced on 2018-06-15

Amount awarded: 1 270 500 PLN

Project start date (Y-m-d): 2019-05-06

Project end date (Y-m-d): 2025-05-05

Project duration:: 36 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Imaging of proteases using activity-based probes
    Authors:
    Mikołaj Żmudziński, Oliwia Malon, Marcin Poręba, Marcin Drąg
    Academic press:
    Current Opinion in Chemical Biology (rok: 2023, tom: 74, strony: 102299), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.cbpa.2023.102299. - link to the publication
  2. Diagnostic and therapeutic potential of protease inhibition.
    Authors:
    Natalia Ćwilichowska, Karolina W Świderska, Agnieszka Dobrzyń, Marcin Drąg, Marcin Poręba
    Academic press:
    Molecular Aspects of Medicine (rok: 2022, tom: 88, strony: 45316), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.mam.2022.101144. - link to the publication
  3. Multiplexed Probing of Proteolytic Enzymes Using Mass Cytometry-Compatible Activity-Based Probes
    Authors:
    Marcin Poreba, Katarzyna M Groborz, Wioletta Rut , Milind Pore, Scott J Snipas, Matej Vizovisek , Boris Turk, Peter Kuhn , Marcin Drag , Guy S Salvesen
    Academic press:
    Journal of the American Chemical Society (rok: 2020, tom: 142, strony: 16704-16715), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/jacs.0c06762 - link to the publication

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