Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Solid phase microextraction-based universal analytical platform for assessment of in vitro generated metabolism

2016/23/N/NZ7/01929

Keywords:

Metabolism 3R IVIVE SPME LC-MS cell cultures liver microsomes

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

woj. kujawsko-pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Karol Jaroch 

Number of co-investigators in the project: 2

Call: PRELUDIUM 12 - announced on 2016-09-15

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2017-07-13

Project end date (Y-m-d): 2020-07-12

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Statyw do autosamplera Thermo Q-Exactive Orbitrap przystosowany do płytek 96-dołkowych (2 szt.) (2 400 PLN)
  2. kontener do przechowywania próbek w ciekłym azocie typu "Dewar" YDS-20.
  3. Drukarka 3D (5 000 PLN)
  4. Rotor do wirówki odpowiedni do wirowania płytek 96-dołkowych (7 000 PLN)
  5. Wirówka laboratoryjna wraz z rotorem na płytki 2 x 96-dołkowa.

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (1)
  1. Untargeted screening of phase I metabolism of combretastatin A4 by multitool analysis
    Authors:
    Karol Jaroch, Paulina Zofia Goryńska, Krzysztof Goryński, Tomasz Stefański, Barbara Bojko
    Academic press:
    Talanta (rok: 2018, tom: 182, strony: 22–31), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.talanta.2018.01.051 - link to the publication
  1. UNREVEALING PHASE I METABOLISM OF COMBRETASTATIN A4 BY A MULTI-TOOL MS-BASED APPROACH
    Authors:
    Karol Jaroch, Paulina Zofia Goryńska, Krzysztof Goryński, Tomasz Stefański, Barbara Bojko
    Conference:
    INTERNATIONAL MASS SPECTROMETRY CONFERENCE (IMSC) 2018 (rok: 2018, ), Wydawca: Societa Chimica Italiana, International Mass Spectrometry Foundation
    Data:
    konferencja 26-31.08
    Status:
    Published

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