Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Application of ene-reductases in enzymatic, stereoselective synthesis of heteroorganic compounds

2016/21/N/ST5/03361

Keywords:

biocatalysis ene-reductases stereoselective reduction phosphonates

Descriptors:

  • ST5_23:
  • ST5_16:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Ignacy Janicki 

Number of co-investigators in the project: 2

Call: PRELUDIUM 11 - announced on 2016-03-15

Amount awarded: 99 960 PLN

Project start date (Y-m-d): 2017-03-08

Project end date (Y-m-d): 2019-03-07

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Wirówka Laboratoryjna (4 529 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Asymmetric Bioreduction of B-Activated Vinylphosphonate Derivatives Using Ene-Reductases
    Authors:
    Ignacy Janicki, Piotr Kiełbasiński, Nikolaus G. Turrini, Kurt Faber, Melanie Hall
    Academic press:
    Advanced Synthesis & Catalysis (rok: 2017, tom: 359, strony: 4067, 4190-4196), Wydawca: WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
    Status:
    Published
    DOI:
    10.1002/adsc.201700716 - link to the publication
  2. Application of the Z-Selective Still–Gennari Olefination Protocol for the Synthesis of Z-α,β-Unsaturated Phosphonates
    Authors:
    Ignacy Janicki, Piotr Kiełbasiński
    Academic press:
    Synthesis (rok: 2018, tom: 50, strony: 4140-4144), Wydawca: Georg Thieme Verlag Stuttgart
    Status:
    Published
    DOI:
    10.1055/s-0037-1609562; - link to the publication
  3. Preparative scale application of Mucor circinelloides ene–reductase and alcohol dehydrogenase activity for the asymmetric bioreduction of α,β-unsaturated γ-ketophosphonates
    Authors:
    Ignacy Janicki, Piotr Kiełbasiński, Jakub Szeląg, Adrian Głębski, Mirosława Szczęsna-Antczak
    Academic press:
    Bioorganic Chemistry (rok: 2020, tom: 96, strony: 103548), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bioorg.2019.103548 - link to the publication

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