Projects funded by the NCN

Integrative analysis of tRNA modification circuits and aminoacylation and their role in breast cancer model.

Call: OPUS 29 , Panel: NZ2

Principal investigator: dr Marcin Sajek

Instytut Genetyki Człowieka PAN

Decoding the code: Unraveling the role of human methyltransferase Trm5 in tRNA modification

Call: PRELUDIUM 24 , Panel: NZ1

Principal investigator: Julia Aleksandra Sikorska

Uniwersytet Warszawski

Molecular analyses of human dihydrouridine synthases acting on tRNA

Call: SONATA BIS 14 , Panel: NZ1

Principal investigator: dr Monika Ewelina Gaik

Uniwersytet Jagielloński

Deciphering the Molecular Mechanism of Queuosinylation of Human tRNA: Structural and Functional Analyses of the QTRT1/2 ...

Call: PRELUDIUM 23 , Panel: NZ1

Principal investigator: Igor Kaczmarczyk

Uniwersytet Jagielloński

The role of tRNA thiolation in human disease

Call: OPUS 26 (LAP) , Panel: NZ1

Principal investigator: dr hab. Sebastian Glatt

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

tRNA-derived fragments as stress responsive and regulating agents in soybean

Call: OPUS 24 , Panel: NZ9

Principal investigator: dr hab. Agata Tyczewska

Instytut Chemii Bioorganicznej PAN

Linkage between Maf1-mediated control of tRNA transcription and mRNA translation in Saccharomyces cerevisiae yeast

Call: PRELUDIUM 21 , Panel: NZ1

Principal investigator: Alicja Agata Armatowska

Instytut Biochemii i Biofizyki PAN

The Elongator protein complex integrates regulation of transcription and translation during photomorphogenesis in Arabid...

Call: OPUS 22 , Panel: NZ1

Principal investigator: dr hab. Magdalena Paula Wołoszyńska

Uniwersytet Przyrodniczy we Wrocławiu

A tRNA-like structure in gene encoding Maf1, a general repressor of tRNA transcription: possible regulatory implications

Call: PRELUDIUM BIS 3 , Panel: NZ1

Principal investigator: prof. Magdalena Rakowska-Boguta

Instytut Biochemii i Biofizyki PAN

Synthesis and structural/biophysical studies of model mRNA/mt-tRNA oligomers to evaluate the role of modified nucleoside...

Call: OPUS 22 , Panel: ST4

Principal investigator: dr hab. Grażyna Bożena Leszczyńska

Politechnika Łódzka

The role of tRNA expression and modification in chloroplast translation during stress

Call: SONATA BIS 11 , Panel: NZ3

Principal investigator: dr hab. Piotr Gawroński

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

Molecular mechanisms linking RNA polymerase III mutations to Hypomyelinating leukodystrophy (HLD).

Call: SONATA 16 , Panel: NZ2

Principal investigator: dr Tomasz Wojciech Turowski

Instytut Biochemii i Biofizyki PAN

New aspects of negative regulation of RNA polymerase III in yeast Saccharomyces cerevisiae

Call: OPUS 17 , Panel: NZ1

Principal investigator: dr Małgorzata Maria Cieśla

Instytut Biochemii i Biofizyki PAN

Molecular Characterization of large tRNA modification Complexes

Call: OPUS 16 , Panel: NZ1

Principal investigator: dr Sebastian Glatt

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Why Nature introduced selenium to wobble nucleosides in transfer RNA?

Call: OPUS 15 , Panel: ST5

Principal investigator: prof. Barbara Czesława Nawrot

Centrum Badań Molekularnych i Makromolekularnych PAN

Identification of tRNA-like sequences from Arabidopsis thaliana

Call: OPUS 14 , Panel: NZ2

Principal investigator: prof. Wojciech Maciej Karłowski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

The role of Rbs1 protein in control of general response to defect in tRNA biosynthesis in yeast Saccharomyces cerevisiae

Call: OPUS 13 , Panel: NZ1

Principal investigator: prof. Magdalena Rakowska-Boguta

Instytut Biochemii i Biofizyki PAN

Synthesis and structural studies of oligonucleotides with tRNA anticodon stem-loop sequences containing newly discovered...

Call: OPUS 13 , Panel: ST5

Principal investigator: prof. Elżbieta Jadwiga Sochacka

Politechnika Łódzka, Wydział Chemiczny

Studies on the 2-thiouridine tRNA damage induced in the cells under oxidative stress

Call: OPUS 12 , Panel: NZ1

Principal investigator: dr Małgorzata Barbara Sierant

Centrum Badań Molekularnych i Makromolekularnych PAN

Catalytic RNS's as a tool for human mitochondrial biotechnology

Call: PRELUDIUM 11 , Panel: NZ1

Principal investigator: Paweł Mariusz Głodowicz

Instytut Chemii Bioorganicznej PAN

Functional analysis of small RNAs, derived from tRNAs in a model organism Arabidopsis thaliana.

Call: PRELUDIUM 10 , Panel: NZ2

Principal investigator: Agnieszka Thompson

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Regulatory Networks of the eukaryotic Elongator Complex

Call: OPUS 10 , Panel: NZ1

Principal investigator: dr Sebastian Glatt

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Studies on the synthesis of newly discovered cyclic N6-threonylcarbamoyladenosine (ct6A) and its analogues and on the in...

Call: PRELUDIUM 7 , Panel: ST5

Principal investigator: Michał Robert Matuszewski

Politechnika Łódzka, Wydział Chemiczny

Biosynthesis of seleno-modified nucleosides in the anticodon loop of transfer ribonucleic acids. Evaluation of the enzym...

Call: OPUS 7 , Panel: ST5

Principal investigator: prof. Barbara Czesława Nawrot

Centrum Badań Molekularnych i Makromolekularnych PAN

Functional analysis of selected tRFs in Arabidopsis thaliana

Call: PRELUDIUM 6 , Panel: NZ2

Principal investigator: Patrycja Plewka

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Role of stringent factors and sequence of discriminator in transcription regulation from tRNA promoters during stress co...

Call: SONATA 5 , Panel: NZ1

Principal investigator: dr Robert Łyżeń

Uniwersytet Gdański, Wydział Biologii

Investigation of interplay of tRNA transcription, processing and decay in yeast Saccharomyces cerevisiae.

Call: PRELUDIUM 5 , Panel: NZ1

Principal investigator: dr Dominika Foretek

Instytut Biochemii i Biofizyki PAN

Structure - activity relationship studies of new flavonoids derivatives as the inhibitors of the bacterial tyrosyl-tRNA ...

Call: PRELUDIUM 3 , Panel: NZ7

Principal investigator: dr Mirosława Anna Skupińska

Instytut Chemii Bioorganicznej PAN

tRNA transcription: novel layers of regulation

Call: MAESTRO 2 , Panel: NZ1

Principal investigator: prof. Magdalena Rakowska-Boguta

Instytut Biochemii i Biofizyki PAN

Identification, biogenesis and functional analysis of tRNA-derived small RNAs in Arabidopsis thaliana

Call: OPUS 2 , Panel: NZ2

Principal investigator: prof. Wojciech Karłowski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Studies on the desulfuration of 2-thiouridines in relation to tRNA damage in oxidative stress conditions

Call: OPUS 2 , Panel: ST5

Principal investigator: prof. Barbara Czesława Nawrot

Centrum Badań Molekularnych i Makromolekularnych PAN

Role of the human RNA exosome catalytic subunit DIS3 in multiple myeloma pathogenesis and cell physiology.

Call: MAESTRO 1 , Panel: NZ1

Principal investigator: prof. Andrzej Stanisław Dziembowski

Uniwersytet Warszawski, Wydział Biologii

The tRNA/cytochrome C complex formation and its role in programmed cell death

Call: OPUS 1 , Panel: NZ3

Principal investigator: dr hab. Arkadiusz Chworoś

Centrum Badań Molekularnych i Makromolekularnych PAN

The role of Maf1 protein, repressor of Pol III RNA, in controlling tRNA stabilization

Call: PRELUDIUM 1 , Panel: NZ1

Principal investigator: dr Tomasz Wojciech Turowski

Politechnika Warszawska, Wydział Chemiczny